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Article: Subfamilies of cpmA, a gene involved in circadian output, have different evolutionary histories in cyanobacteria

TitleSubfamilies of cpmA, a gene involved in circadian output, have different evolutionary histories in cyanobacteria
Authors
Issue Date2006
PublisherSociety for General Microbiology. The Journal's web site is located at http://mic.sgmjournals.org
Citation
Microbiology, 2006, v. 152 n. 1, p. 75-84 How to Cite?
AbstractThe cpmA gene mediates an output signal in the cyanobacterial circadian system. This gene and its homologues are evolutionarily old, and occur in some non-photosynthetic bacteria and archaea as well as in cyanobacteria. The gene has two functional domains that differ drastically in their level of polymorphism: the N-terminal domain is much more variable than the PurE homologous C-terminal domain. The phylogenetic tree of the cpmA homologues features four main clades (C1-C4), two of which (C1 and C3) belong to cyanobacteria. These cyanobacterial clades match respective ones in the previously reported phylogenetic trees of the other genes involved in the circadian system. The phylogenetic analysis suggested that the C3 subfamily, which comprises the genes from the cyanobacteria with the kaiBC-based circadian system, experienced a lateral transfer, probably from evolutionarily old proteobacteria about 1000 million years ago. The genes of this subfamily have a significantly higher nonsynonymous substitution rate than those of C1 (2.13 × 10-10 and 1.53 × 10-10 substitutions per nonsynonymous site per year, respectively). It appears that the functional and selective constraints of the kaiABC-based system have slowed down the rate of sequence evolution compared to the cpmA homologues of the kaiBC-based system. On the other hand, the differences in the mutation rates between the two cyanobacterial clades point to the different functional constraints of the systems with or without kaiA. © 2006 SGM.
Persistent Identifierhttp://hdl.handle.net/10722/178924
ISSN
2015 Impact Factor: 2.268
2015 SCImago Journal Rankings: 1.144
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorDvornyk, Ven_US
dc.date.accessioned2012-12-19T09:50:46Z-
dc.date.available2012-12-19T09:50:46Z-
dc.date.issued2006en_US
dc.identifier.citationMicrobiology, 2006, v. 152 n. 1, p. 75-84en_US
dc.identifier.issn1350-0872en_US
dc.identifier.urihttp://hdl.handle.net/10722/178924-
dc.description.abstractThe cpmA gene mediates an output signal in the cyanobacterial circadian system. This gene and its homologues are evolutionarily old, and occur in some non-photosynthetic bacteria and archaea as well as in cyanobacteria. The gene has two functional domains that differ drastically in their level of polymorphism: the N-terminal domain is much more variable than the PurE homologous C-terminal domain. The phylogenetic tree of the cpmA homologues features four main clades (C1-C4), two of which (C1 and C3) belong to cyanobacteria. These cyanobacterial clades match respective ones in the previously reported phylogenetic trees of the other genes involved in the circadian system. The phylogenetic analysis suggested that the C3 subfamily, which comprises the genes from the cyanobacteria with the kaiBC-based circadian system, experienced a lateral transfer, probably from evolutionarily old proteobacteria about 1000 million years ago. The genes of this subfamily have a significantly higher nonsynonymous substitution rate than those of C1 (2.13 × 10-10 and 1.53 × 10-10 substitutions per nonsynonymous site per year, respectively). It appears that the functional and selective constraints of the kaiABC-based system have slowed down the rate of sequence evolution compared to the cpmA homologues of the kaiBC-based system. On the other hand, the differences in the mutation rates between the two cyanobacterial clades point to the different functional constraints of the systems with or without kaiA. © 2006 SGM.en_US
dc.languageengen_US
dc.publisherSociety for General Microbiology. The Journal's web site is located at http://mic.sgmjournals.orgen_US
dc.relation.ispartofMicrobiologyen_US
dc.subject.meshBacterial Proteins - Geneticsen_US
dc.subject.meshCircadian Rhythmen_US
dc.subject.meshEvolution, Molecularen_US
dc.subject.meshGenes, Bacterialen_US
dc.subject.meshMutationen_US
dc.subject.meshPolymorphism, Geneticen_US
dc.subject.meshSpecies Specificityen_US
dc.subject.meshSynechococcus - Genetics - Physiologyen_US
dc.titleSubfamilies of cpmA, a gene involved in circadian output, have different evolutionary histories in cyanobacteriaen_US
dc.typeArticleen_US
dc.identifier.emailDvornyk, V: dvornyk@hku.hken_US
dc.identifier.authorityDvornyk, V=rp00693en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1099/mic.0.28400-0en_US
dc.identifier.pmid16385117-
dc.identifier.scopuseid_2-s2.0-30744470632en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-30744470632&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume152en_US
dc.identifier.issue1en_US
dc.identifier.spage75en_US
dc.identifier.epage84en_US
dc.identifier.isiWOS:000234741400009-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridDvornyk, V=6701789786en_US

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