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Article: The nucleotide sequence of rabbit liver transferrin cDNA

TitleThe nucleotide sequence of rabbit liver transferrin cDNA
Authors
Issue Date1991
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/bbaexp
Citation
Biochimica Et Biophysica Acta - Gene Structure And Expression, 1991, v. 1089 n. 2, p. 262-265 How to Cite?
AbstractThe cDNA sequence of rabbit liver transferrin has been determined. The largest cDNA was 2279 base pairs (bp) in size and encoded 694 amino acids consisting of a putative 19 amino acid signal peptide and 675 amino acids of plasma transferrin. The deduced amino acid sequence of rabbit liver transferrin shares 78.5% identity with human liver transferrin and 69.1% and 44.8% identity with porcine and Xenopus transferrins, respectively. At the amino acid level, vertebrate transferrins share 26.4% identity and 56.5% similarity. The most conserved regions correspond to the iron ligands and the anion binding region. Optimal alignment of transferrin sequences required the insertion of a number of gaps in the region corresponding to the N-lobe. In addition, the N-lobes of transferrins share less amino acid sequence similarity than the C-lobes.
Persistent Identifierhttp://hdl.handle.net/10722/178504
ISSN
2007 Impact Factor: 1.704
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorBanfield, DKen_US
dc.contributor.authorChow, BKCen_US
dc.contributor.authorFunk, WDen_US
dc.contributor.authorRobertson, KAen_US
dc.contributor.authorUmelas, TMen_US
dc.contributor.authorWoodworth, RCen_US
dc.contributor.authorMacgillivray, RTAen_US
dc.date.accessioned2012-12-19T09:48:05Z-
dc.date.available2012-12-19T09:48:05Z-
dc.date.issued1991en_US
dc.identifier.citationBiochimica Et Biophysica Acta - Gene Structure And Expression, 1991, v. 1089 n. 2, p. 262-265en_US
dc.identifier.issn0167-4781en_US
dc.identifier.urihttp://hdl.handle.net/10722/178504-
dc.description.abstractThe cDNA sequence of rabbit liver transferrin has been determined. The largest cDNA was 2279 base pairs (bp) in size and encoded 694 amino acids consisting of a putative 19 amino acid signal peptide and 675 amino acids of plasma transferrin. The deduced amino acid sequence of rabbit liver transferrin shares 78.5% identity with human liver transferrin and 69.1% and 44.8% identity with porcine and Xenopus transferrins, respectively. At the amino acid level, vertebrate transferrins share 26.4% identity and 56.5% similarity. The most conserved regions correspond to the iron ligands and the anion binding region. Optimal alignment of transferrin sequences required the insertion of a number of gaps in the region corresponding to the N-lobe. In addition, the N-lobes of transferrins share less amino acid sequence similarity than the C-lobes.en_US
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/bbaexpen_US
dc.relation.ispartofBiochimica et Biophysica Acta - Gene Structure and Expressionen_US
dc.subject.meshAmino Acid Sequenceen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBase Sequenceen_US
dc.subject.meshDna - Geneticsen_US
dc.subject.meshHumansen_US
dc.subject.meshIron Chelating Agents - Metabolismen_US
dc.subject.meshLiver - Metabolismen_US
dc.subject.meshMolecular Sequence Dataen_US
dc.subject.meshRatsen_US
dc.subject.meshSequence Homology, Nucleic Aciden_US
dc.subject.meshSwineen_US
dc.subject.meshTransferrin - Geneticsen_US
dc.subject.meshXenopusen_US
dc.titleThe nucleotide sequence of rabbit liver transferrin cDNAen_US
dc.typeArticleen_US
dc.identifier.emailChow, BKC: bkcc@hku.hken_US
dc.identifier.authorityChow, BKC=rp00681en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0167-4781(91)90021-Den_US
dc.identifier.pmid2054387-
dc.identifier.scopuseid_2-s2.0-0025758445en_US
dc.identifier.volume1089en_US
dc.identifier.issue2en_US
dc.identifier.spage262en_US
dc.identifier.epage265en_US
dc.identifier.isiWOS:A1991FU40000021-
dc.publisher.placeNetherlandsen_US
dc.identifier.scopusauthoridBanfield, DK=7004715266en_US
dc.identifier.scopusauthoridChow, BKC=7102826193en_US
dc.identifier.scopusauthoridFunk, WD=7102648307en_US
dc.identifier.scopusauthoridRobertson, KA=8861350200en_US
dc.identifier.scopusauthoridUmelas, TM=8861350300en_US
dc.identifier.scopusauthoridWoodworth, RC=7006217057en_US
dc.identifier.scopusauthoridMacGillivray, RTA=7004286039en_US

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