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  Patent History
  • Application
    US 11/875271 2007-10-19
  • Granted
    US 7645616 2010-01-12

granted patent: USE OF LIPOCALIN-2 AS A DIAGNOSTIC MARKER AND THERAPEUTIC TARGET

TitleUSE OF LIPOCALIN-2 AS A DIAGNOSTIC MARKER AND THERAPEUTIC TARGET
Granted PatentUS 7645616
Granted Date2010-01-12
Priority Date2007-10-19 US 11/875271
2006-10-20 US 11/853404P
Inventors
Issue Date2010
Citation
US Patent US 7645616. Washington, DC: US Patent and Trademark Office (USPTO), 2010 How to Cite?
AbstractMethods and compositions for identifying and treating obesity and obesity-induced metabolic disorders are provided. One aspect provides a method for the evaluation of risk and progression of glucose tolerance, insulin resistance and Type 2 diabetes in mammalian subjects. The method includes measuring the concentration of circulating lipocalin-2 in a subject and comparing the measured level to lipocalin-2 to a reference level. Another aspect provides methods of treating insulin resistance, type 2 diabetes and other related complications by administering to a patient a composition that can reduce the circulating levels of lipocalin-2, for example a lipocalin-2 antagonist.
Persistent Identifierhttp://hdl.handle.net/10722/177041
References

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:59Z-
dc.date.available2012-11-30T08:38:59Z-
dc.date.issued2010-
dc.identifier.citationUS Patent US 7645616. Washington, DC: US Patent and Trademark Office (USPTO), 2010en_HK
dc.identifier.urihttp://hdl.handle.net/10722/177041-
dc.description.abstractMethods and compositions for identifying and treating obesity and obesity-induced metabolic disorders are provided. One aspect provides a method for the evaluation of risk and progression of glucose tolerance, insulin resistance and Type 2 diabetes in mammalian subjects. The method includes measuring the concentration of circulating lipocalin-2 in a subject and comparing the measured level to lipocalin-2 to a reference level. Another aspect provides methods of treating insulin resistance, type 2 diabetes and other related complications by administering to a patient a composition that can reduce the circulating levels of lipocalin-2, for example a lipocalin-2 antagonist.en_HK
dc.relation.isreferencedbyEP 2300048 (A1) 2011-03-30en_HK
dc.relation.isreferencedbyEP 2300048 (A4) 2011-08-24en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleUSE OF LIPOCALIN-2 AS A DIAGNOSTIC MARKER AND THERAPEUTIC TARGETen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorXu, Aen_HK
dc.contributor.inventorWang, Yen_HK
dc.contributor.inventorLam, KSLen_HK
patents.identifier.applicationUS 11/875271en_HK
patents.identifier.grantedUS 7645616en_HK
patents.description.assigneeUNIV HONG KONG [HK]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.granted2010-01-12en_HK
dc.relation.referencesUS 2003157580 (A1) 2003-08-21en_HK
dc.relation.referencesUS 7368247 (B2) 2008-05-06en_HK
dc.relation.referencesUS 2007196876 (A1) 2007-08-23en_HK
dc.relation.referencesUS 3832253 (A) 1974-08-27en_HK
dc.relation.referencesUS 3854480 (A) 1974-12-17en_HK
dc.relation.referencesUS 4452775 (A) 1984-06-05en_HK
dc.relation.referencesUS 4667013 (A) 1987-05-19en_HK
dc.relation.referencesUS 4675189 (A) 1987-06-23en_HK
dc.relation.referencesUS 4748034 (A) 1988-05-31en_HK
dc.relation.referencesUS 5075109 (A) 1991-12-24en_HK
dc.relation.referencesUS 5133974 (A) 1992-07-28en_HK
dc.relation.referencesUS 5239660 (A) 1993-08-24en_HK
dc.relation.referencesUS 5407686 (A) 1995-04-18en_HK
dc.relation.referencesUS 5702902 (A) 1997-12-30en_HK
dc.relation.referencesUS 5736152 (A) 1998-04-07en_HK
dc.relation.referencesUS 2002034821 (A1) 2002-03-21en_HK
dc.relation.referencesUS 6919208 (B2) 2005-07-19en_HK
patents.identifier.hkutechidMedi-2006-00232-1-
patents.date.application2007-10-19en_HK
patents.date.priority2007-10-19 US 11/875271en_HK
patents.date.priority2006-10-20 US 11/853404Pen_HK
patents.description.ccUSen_HK
patents.relation.familyUS 2008095782 (A1) 2008-04-24en_HK
patents.relation.familyUS 7645616 (B2) 2010-01-12en_HK
patents.relation.familyUS 2010310578 (A1) 2010-12-09en_HK
patents.relation.familyWO 2008049330 (A1) 2008-05-02en_HK
patents.description.kindB2en_HK
patents.typePatent_granteden_HK

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