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  Patent History
  • Application
    AU 20030210119 2003-02-24
  • Publication
    AU 2003210119 2003-09-16
Supplementary

published patent: METHOD FOR SYNTHESIZING 5ss, 6ss-EPOXIDES OF STEROIDS BY A HIGHLY ss-SELECTIVE EPOXIDATION OF Delta5-UNSATURATED STEROIDS CATALYZED BY KETONES

TitleMETHOD FOR SYNTHESIZING 5ss, 6ss-EPOXIDES OF STEROIDS BY A HIGHLY ss-SELECTIVE EPOXIDATION OF Delta5-UNSATURATED STEROIDS CATALYZED BY KETONES
Priority Date2003-02-24 PCT/CN2003000140
2002-03-06 US 10/091627
Inventors
Issue Date2003
Citation
Australia Published Patent Application AU 2003210119. Australia: IP Australia, 2003 How to Cite?
AbstractA general, efficient, and environmentally friendly method is provided for producing mostly beta-epoxides of DELTA5-unsaturated steroids using certain ketones as the catalyst along with an oxidizing agent, or by using certain dioxiranes. In another aspect of the invention, a method is provided for producing mostly 5beta,6beta-epoxides of steroids from DELTA5-unsaturated steroids having a substituent at the 3alpha-position by an epoxidation reaction using a ketone along with an oxidizing agent under conditions effective to generate epoxides, or using a dioxirane under conditions effective to generate epoxides.; A whole range of DELTA5-unsaturated steroids, bearing different functional groups such as hydroxy, carbonyl, acetyl or ketal group as well as different side chains, were conveniently converted to the corresponding synthetically and biologically interesting 5beta,6beta-epoxides with excellent beta-selectivities and high yields.
Persistent Identifierhttp://hdl.handle.net/10722/176531

 

DC FieldValueLanguage
dc.date.accessioned2012-11-30T08:38:05Z-
dc.date.available2012-11-30T08:38:05Z-
dc.date.issued2003-
dc.identifier.citationAustralia Published Patent Application AU 2003210119. Australia: IP Australia, 2003en_HK
dc.identifier.urihttp://hdl.handle.net/10722/176531-
dc.description.abstractA general, efficient, and environmentally friendly method is provided for producing mostly beta-epoxides of DELTA5-unsaturated steroids using certain ketones as the catalyst along with an oxidizing agent, or by using certain dioxiranes. In another aspect of the invention, a method is provided for producing mostly 5beta,6beta-epoxides of steroids from DELTA5-unsaturated steroids having a substituent at the 3alpha-position by an epoxidation reaction using a ketone along with an oxidizing agent under conditions effective to generate epoxides, or using a dioxirane under conditions effective to generate epoxides.; A whole range of DELTA5-unsaturated steroids, bearing different functional groups such as hydroxy, carbonyl, acetyl or ketal group as well as different side chains, were conveniently converted to the corresponding synthetically and biologically interesting 5beta,6beta-epoxides with excellent beta-selectivities and high yields.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documentsen_US
dc.titleMETHOD FOR SYNTHESIZING 5ss, 6ss-EPOXIDES OF STEROIDS BY A HIGHLY ss-SELECTIVE EPOXIDATION OF Delta5-UNSATURATED STEROIDS CATALYZED BY KETONESen_HK
dc.typePatenten_US
dc.description.naturepublished_or_final_versionen_US
dc.contributor.inventorYang, Den_HK
dc.contributor.inventorGuansheng Jiaoen_HK
patents.identifier.applicationAU 20030210119en_HK
patents.description.assigneeUNIV HONG KONGen_HK
patents.description.countryAustraliaen_HK
patents.date.publication2003-09-16en_HK
patents.date.application2003-02-24en_HK
patents.date.priority2003-02-24 PCT/CN2003000140en_HK
patents.date.priority2002-03-06 US 10/091627en_HK
patents.description.ccAUen_HK
patents.identifier.publicationAU 2003210119en_HK
patents.relation.familyAU 2003210119 (A1) 2003-09-16en_HK
patents.relation.familyUS 2003018188 (A1) 2003-01-23en_HK
patents.relation.familyUS 6841665 (B2) 2005-01-11en_HK
patents.relation.familyWO 03074545 (A1) 2003-09-12en_HK
patents.description.kindA1en_HK
patents.typePatent_publisheden_HK

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