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Article: Five-year follow up of selective laser trabeculoplasty in Chinese eyes

TitleFive-year follow up of selective laser trabeculoplasty in Chinese eyes
Authors
Issue Date2004
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CEO
Citation
Clinical And Experimental Ophthalmology, 2004, v. 32 n. 4, p. 368-372 How to Cite?
AbstractPurpose: To study the effectiveness and safety of selective laser trabeculoplasty (SLT) on primary open-angle glaucoma and ocular hypertension in Chinese eyes. Methods: This was a prospective randomized controlled clinical study in which 58 eyes of 29 patients with primary open-angle glaucoma or ocular hypertension were included. One eye of each patient was randomized to receive SLT (Group 1) and the fellow eyes received medical treatment (Group 2). Patients were evaluated after laser treatment at 2 h, 1 day, 1 week, 2 weeks, 1 month, 3 months, 6 months, and then yearly. Results: All patients (13 male, 16 female) were Chinese. The mean age was 51.9 ± 14.7 years. The mean baseline intraocular pressure was 26.8 ± 5.6 mmHg in group 1 and 26.2 ± 4.2 mmHg in group 2 (P = 0.62). The failure rate, defined as intraocular pressure >21 mmHg with maximal medications, was 17.2% in group 1 and 27.6% in group 2 at 5-year follow-up (P = 0.53). Fight eyes (27.6%) in group 1 required medications to control the intraocular pressure to below 21 mmHg. There was no statistically significant difference in the intraocular pressure reductions between the two groups at all time intervals (P > 0.05). The mean number of antiglaucoma medications was significantly lower in the SLT than the medical treatment group up to 5 years of follow up (P < 0.001). Transient post-SLT intraocular pressure spike >5 mmHg was observed in three eyes (10.3%). Conclusion: With fewer medications, SLT gives similar intraocular pressure reduction to medical therapy alone in Chinese patients with primary open-angle glaucoma or ocular hypertension.
Persistent Identifierhttp://hdl.handle.net/10722/176473
ISSN
2015 Impact Factor: 2.546
2015 SCImago Journal Rankings: 1.335
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLai, JSMen_US
dc.contributor.authorChua, JKHen_US
dc.contributor.authorTham, CCYen_US
dc.contributor.authorLam, DSCen_US
dc.date.accessioned2012-11-26T09:11:39Z-
dc.date.available2012-11-26T09:11:39Z-
dc.date.issued2004en_US
dc.identifier.citationClinical And Experimental Ophthalmology, 2004, v. 32 n. 4, p. 368-372en_US
dc.identifier.issn1442-6404en_US
dc.identifier.urihttp://hdl.handle.net/10722/176473-
dc.description.abstractPurpose: To study the effectiveness and safety of selective laser trabeculoplasty (SLT) on primary open-angle glaucoma and ocular hypertension in Chinese eyes. Methods: This was a prospective randomized controlled clinical study in which 58 eyes of 29 patients with primary open-angle glaucoma or ocular hypertension were included. One eye of each patient was randomized to receive SLT (Group 1) and the fellow eyes received medical treatment (Group 2). Patients were evaluated after laser treatment at 2 h, 1 day, 1 week, 2 weeks, 1 month, 3 months, 6 months, and then yearly. Results: All patients (13 male, 16 female) were Chinese. The mean age was 51.9 ± 14.7 years. The mean baseline intraocular pressure was 26.8 ± 5.6 mmHg in group 1 and 26.2 ± 4.2 mmHg in group 2 (P = 0.62). The failure rate, defined as intraocular pressure >21 mmHg with maximal medications, was 17.2% in group 1 and 27.6% in group 2 at 5-year follow-up (P = 0.53). Fight eyes (27.6%) in group 1 required medications to control the intraocular pressure to below 21 mmHg. There was no statistically significant difference in the intraocular pressure reductions between the two groups at all time intervals (P > 0.05). The mean number of antiglaucoma medications was significantly lower in the SLT than the medical treatment group up to 5 years of follow up (P < 0.001). Transient post-SLT intraocular pressure spike >5 mmHg was observed in three eyes (10.3%). Conclusion: With fewer medications, SLT gives similar intraocular pressure reduction to medical therapy alone in Chinese patients with primary open-angle glaucoma or ocular hypertension.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CEOen_US
dc.relation.ispartofClinical and Experimental Ophthalmologyen_US
dc.subject.meshAsian Continental Ancestry Group - Ethnologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshGlaucoma, Open-Angle - Ethnology - Surgeryen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIntraocular Pressureen_US
dc.subject.meshLaser Therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshOcular Hypertension - Ethnology - Surgeryen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshSafetyen_US
dc.subject.meshTonometry, Ocularen_US
dc.subject.meshTrabecular Meshwork - Surgeryen_US
dc.subject.meshTrabeculectomy - Methodsen_US
dc.titleFive-year follow up of selective laser trabeculoplasty in Chinese eyesen_US
dc.typeArticleen_US
dc.identifier.emailLai, JSM: laism@hku.hken_US
dc.identifier.authorityLai, JSM=rp00295en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1442-9071.2004.00839.xen_US
dc.identifier.pmid15281969-
dc.identifier.scopuseid_2-s2.0-4444348608en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-4444348608&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume32en_US
dc.identifier.issue4en_US
dc.identifier.spage368en_US
dc.identifier.epage372en_US
dc.identifier.isiWOS:000223473200007-
dc.publisher.placeAustraliaen_US
dc.identifier.scopusauthoridLai, JSM=7401939748en_US
dc.identifier.scopusauthoridChua, JKH=7005163724en_US
dc.identifier.scopusauthoridTham, CCY=7006081241en_US
dc.identifier.scopusauthoridLam, DSC=35500200200en_US

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