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Article: Diode laser transscleral cyclophotocoagulation in the treatment of chronic angle-closure glaucoma: A preliminary study

TitleDiode laser transscleral cyclophotocoagulation in the treatment of chronic angle-closure glaucoma: A preliminary study
Authors
Issue Date2003
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.glaucomajournal.com
Citation
Journal Of Glaucoma, 2003, v. 12 n. 4, p. 360-364 How to Cite?
AbstractPurpose: To evaluate the efficacy and safety of diode laser transscleral cyclophotocoagulation in the treatment of chronic angle-closure glaucoma. Patients and Methods: A prospective, non-comparative interventional pilot study was conducted. Fourteen eyes of 14 Chinese patients with chronic angle-closure glaucoma whose intraocular pressures were greater than 21 mm Hg on medications were treated with diode laser transscleral cyclophotocoagulation using the G-probe at the United Christian Hospital between February 2000 and May 2001. The inferior 270° quadrant (from 2 to 11 o'clock for right eye and from 1 to 10 o'clock for left eye) was treated and the patients were followed up regularly. The initial laser energy was set at 2000 mWatt with a duration of 2 seconds. The post-treatment anti-glaucoma medications were adjusted according to the intraocular pressure. If medications failed to lower the intraocular pressure to below 21 mm Hg, cyclophotocoagulation to the same inferior 270° quadrant was repeated. Results: All patients completed a 12-month follow-up period. The total success rate defined as IOP < 21 mm Hg with or without medication(s) was 85.7% at 1 year of follow-up review. The mean ± SD intraocular pressure decreased from pre-treatment level of 36.9 ± 11.7 mm Hg to 18.9 ± 6.5 mm Hg at 1 year after treatment. The difference was statistically significant (P < 0.001) (Paired t test). The mean ± SD number of IOP-lowering eyedrops was significantly reduced from 1.9 ± 0.7 before cyclophotocoagulation to 0.4 ± 0.8 at 1 year after treatment (P = 0.0002) (Paired t test). Two eyes required repeat treatment. Seven eyes (50%) had atonic pupil following the laser treatment. Conclusion: Diode laser transscleral cyclophotocoagulation is effective in lowering the intraocular pressure in chronic angle-closure glaucoma and its effect lasts for at least 1 year.
Persistent Identifierhttp://hdl.handle.net/10722/176404
ISSN
2015 Impact Factor: 2.102
2015 SCImago Journal Rankings: 1.477
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLai, JSMen_US
dc.contributor.authorTham, CCYen_US
dc.contributor.authorChan, JCHen_US
dc.contributor.authorLam, DSCen_US
dc.date.accessioned2012-11-26T09:11:03Z-
dc.date.available2012-11-26T09:11:03Z-
dc.date.issued2003en_US
dc.identifier.citationJournal Of Glaucoma, 2003, v. 12 n. 4, p. 360-364en_US
dc.identifier.issn1057-0829en_US
dc.identifier.urihttp://hdl.handle.net/10722/176404-
dc.description.abstractPurpose: To evaluate the efficacy and safety of diode laser transscleral cyclophotocoagulation in the treatment of chronic angle-closure glaucoma. Patients and Methods: A prospective, non-comparative interventional pilot study was conducted. Fourteen eyes of 14 Chinese patients with chronic angle-closure glaucoma whose intraocular pressures were greater than 21 mm Hg on medications were treated with diode laser transscleral cyclophotocoagulation using the G-probe at the United Christian Hospital between February 2000 and May 2001. The inferior 270° quadrant (from 2 to 11 o'clock for right eye and from 1 to 10 o'clock for left eye) was treated and the patients were followed up regularly. The initial laser energy was set at 2000 mWatt with a duration of 2 seconds. The post-treatment anti-glaucoma medications were adjusted according to the intraocular pressure. If medications failed to lower the intraocular pressure to below 21 mm Hg, cyclophotocoagulation to the same inferior 270° quadrant was repeated. Results: All patients completed a 12-month follow-up period. The total success rate defined as IOP < 21 mm Hg with or without medication(s) was 85.7% at 1 year of follow-up review. The mean ± SD intraocular pressure decreased from pre-treatment level of 36.9 ± 11.7 mm Hg to 18.9 ± 6.5 mm Hg at 1 year after treatment. The difference was statistically significant (P < 0.001) (Paired t test). The mean ± SD number of IOP-lowering eyedrops was significantly reduced from 1.9 ± 0.7 before cyclophotocoagulation to 0.4 ± 0.8 at 1 year after treatment (P = 0.0002) (Paired t test). Two eyes required repeat treatment. Seven eyes (50%) had atonic pupil following the laser treatment. Conclusion: Diode laser transscleral cyclophotocoagulation is effective in lowering the intraocular pressure in chronic angle-closure glaucoma and its effect lasts for at least 1 year.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.glaucomajournal.comen_US
dc.relation.ispartofJournal of Glaucomaen_US
dc.subject.meshAgeden_US
dc.subject.meshChronic Diseaseen_US
dc.subject.meshCiliary Body - Surgeryen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlaucoma, Angle-Closure - Drug Therapy - Physiopathology - Surgeryen_US
dc.subject.meshHumansen_US
dc.subject.meshIntraocular Pressure - Drug Effectsen_US
dc.subject.meshLaser Coagulation - Adverse Effectsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshOphthalmic Solutions - Administration & Dosageen_US
dc.subject.meshPilot Projectsen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshPupil - Radiation Effectsen_US
dc.subject.meshReoperationen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVisual Acuityen_US
dc.titleDiode laser transscleral cyclophotocoagulation in the treatment of chronic angle-closure glaucoma: A preliminary studyen_US
dc.typeArticleen_US
dc.identifier.emailLai, JSM: laism@hku.hken_US
dc.identifier.authorityLai, JSM=rp00295en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/00061198-200308000-00011en_US
dc.identifier.pmid12897582-
dc.identifier.scopuseid_2-s2.0-0141540729en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0141540729&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume12en_US
dc.identifier.issue4en_US
dc.identifier.spage360en_US
dc.identifier.epage364en_US
dc.identifier.isiWOS:000184573700011-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLai, JSM=7401939748en_US
dc.identifier.scopusauthoridTham, CCY=7006081241en_US
dc.identifier.scopusauthoridChan, JCH=26024354100en_US
dc.identifier.scopusauthoridLam, DSC=35500200200en_US

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