File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Statistical methods in psychiatric genetics

TitleStatistical methods in psychiatric genetics
Authors
Issue Date1998
PublisherSage Publications Ltd. The Journal's web site is located at http://smm.sagepub.com
Citation
Statistical Methods In Medical Research, 1998, v. 7 n. 3, p. 279-300 How to Cite?
AbstractMost psychiatric disorders are determined by the complex interplay between genetic and environmental factors. Aetiological research into these complex disorders raises many different questions which require a variety of statistical methods. These include survival analysis for the estimation of morbid risk, structural equation models for the partitioning of phenotypic variances and covariances into genetic and other components, complex segregation analysis to detect loci of major effect, and linkage and association analysis for the localisation and identification of susceptibility genes. Future developments in psychiatric genetics will involve the integration of genetic and epidemiological statistics in order to study the interplay between genetic and environmental factors in the complex pathways which lead to mental disorders.
Persistent Identifierhttp://hdl.handle.net/10722/175779
ISSN
2015 Impact Factor: 4.634
2015 SCImago Journal Rankings: 3.774
References

 

DC FieldValueLanguage
dc.contributor.authorSham, PCen_US
dc.date.accessioned2012-11-26T09:01:14Z-
dc.date.available2012-11-26T09:01:14Z-
dc.date.issued1998en_US
dc.identifier.citationStatistical Methods In Medical Research, 1998, v. 7 n. 3, p. 279-300en_US
dc.identifier.issn0962-2802en_US
dc.identifier.urihttp://hdl.handle.net/10722/175779-
dc.description.abstractMost psychiatric disorders are determined by the complex interplay between genetic and environmental factors. Aetiological research into these complex disorders raises many different questions which require a variety of statistical methods. These include survival analysis for the estimation of morbid risk, structural equation models for the partitioning of phenotypic variances and covariances into genetic and other components, complex segregation analysis to detect loci of major effect, and linkage and association analysis for the localisation and identification of susceptibility genes. Future developments in psychiatric genetics will involve the integration of genetic and epidemiological statistics in order to study the interplay between genetic and environmental factors in the complex pathways which lead to mental disorders.en_US
dc.languageengen_US
dc.publisherSage Publications Ltd. The Journal's web site is located at http://smm.sagepub.comen_US
dc.relation.ispartofStatistical Methods in Medical Researchen_US
dc.subject.meshChromosome Mapping - Statistics & Numerical Dataen_US
dc.subject.meshEpidemiologic Methodsen_US
dc.subject.meshFemaleen_US
dc.subject.meshGenetic Linkage - Geneticsen_US
dc.subject.meshGenetic Predisposition To Diseaseen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMental Disorders - Epidemiology - Geneticsen_US
dc.subject.meshModels, Geneticen_US
dc.titleStatistical methods in psychiatric geneticsen_US
dc.typeArticleen_US
dc.identifier.emailSham, PC: pcsham@hku.hken_US
dc.identifier.authoritySham, PC=rp00459en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1191/096228098677382724en_US
dc.identifier.pmid9803526-
dc.identifier.scopuseid_2-s2.0-0031689373en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031689373&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume7en_US
dc.identifier.issue3en_US
dc.identifier.spage279en_US
dc.identifier.epage300en_US
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridSham, PC=34573429300en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats