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Article: Prevalence of clinically significant depressive symptoms in an epidemiologic sample of community-dwelling elders with milder forms of cognitive impairment in Hong Kong SAR

TitlePrevalence of clinically significant depressive symptoms in an epidemiologic sample of community-dwelling elders with milder forms of cognitive impairment in Hong Kong SAR
Authors
Issue Date2008
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/4294
Citation
International Journal Of Geriatric Psychiatry, 2008, v. 23 n. 6, p. 611-617 How to Cite?
AbstractBackground: Depression and cognitive impairment in later-life have great bearings on public health. The two conditions often co-occur and have mutual implications on short-term risk and long-term prognosis. Method: A two-phase epidemiologic survey on the prevalence of dementia in elders aged 60 and over was conducted in Hong Kong in 2005-2006. In the first phase, 6,100 randomly selected community dwelling elders were assessed with Cantonese version of Mini-Mental State Examination (C-MMSE) and Abbreviated Memory Inventory for Chinese (AMIC). Two thousand and seventy-three subjects were screened positive and invited for second phase cognitive and psychiatric assessment. 35.5% of screen-positive subjects participated in Phase 2 assessment conducted by psychiatrists for diagnosis of dementia. Severity of dementia was determined using Clinical Dementia Rating Scale (CDR). Cornell Scale for Depression in Dementia (CSDD) and a structured bedside cognitive battery were also administered to each subject. Results: 1.7% of subjects with CDR 0.5 and 5.9% of subjects with CDR 1 had clinically significant depressive symptoms (>/= 8 on CSDD). Score on CSDD correlated positively with duration of cognitive symptoms, scores on CIRS and CMMSE in linear regression model. In a logistic regression model, male gender, duration of cognitive symptoms, CIRS and CMMSE was associated with increased risk for clinically significant depressive symptoms. Conclusions: In our sample, milder forms of cognitive impairment were associated with increased risk for depression in the presence of other risk factors such as male gender, higher physical illness burden and longer duration of cognitive symptoms. Copyright © 2007 John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/174241
ISSN
2015 Impact Factor: 2.699
2015 SCImago Journal Rankings: 1.382
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, SSMen_US
dc.contributor.authorLam, LCWen_US
dc.contributor.authorTam, CWCen_US
dc.contributor.authorLui, VWCen_US
dc.contributor.authorChan, WCen_US
dc.contributor.authorWong, Sen_US
dc.contributor.authorWong, Aen_US
dc.contributor.authorTham, MKen_US
dc.contributor.authorHo, KSen_US
dc.contributor.authorChan, WMen_US
dc.contributor.authorChiu, HFKen_US
dc.date.accessioned2012-11-22T02:01:31Z-
dc.date.available2012-11-22T02:01:31Z-
dc.date.issued2008en_US
dc.identifier.citationInternational Journal Of Geriatric Psychiatry, 2008, v. 23 n. 6, p. 611-617en_US
dc.identifier.issn0885-6230en_US
dc.identifier.urihttp://hdl.handle.net/10722/174241-
dc.description.abstractBackground: Depression and cognitive impairment in later-life have great bearings on public health. The two conditions often co-occur and have mutual implications on short-term risk and long-term prognosis. Method: A two-phase epidemiologic survey on the prevalence of dementia in elders aged 60 and over was conducted in Hong Kong in 2005-2006. In the first phase, 6,100 randomly selected community dwelling elders were assessed with Cantonese version of Mini-Mental State Examination (C-MMSE) and Abbreviated Memory Inventory for Chinese (AMIC). Two thousand and seventy-three subjects were screened positive and invited for second phase cognitive and psychiatric assessment. 35.5% of screen-positive subjects participated in Phase 2 assessment conducted by psychiatrists for diagnosis of dementia. Severity of dementia was determined using Clinical Dementia Rating Scale (CDR). Cornell Scale for Depression in Dementia (CSDD) and a structured bedside cognitive battery were also administered to each subject. Results: 1.7% of subjects with CDR 0.5 and 5.9% of subjects with CDR 1 had clinically significant depressive symptoms (>/= 8 on CSDD). Score on CSDD correlated positively with duration of cognitive symptoms, scores on CIRS and CMMSE in linear regression model. In a logistic regression model, male gender, duration of cognitive symptoms, CIRS and CMMSE was associated with increased risk for clinically significant depressive symptoms. Conclusions: In our sample, milder forms of cognitive impairment were associated with increased risk for depression in the presence of other risk factors such as male gender, higher physical illness burden and longer duration of cognitive symptoms. Copyright © 2007 John Wiley & Sons, Ltd.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/4294en_US
dc.relation.ispartofInternational Journal of Geriatric Psychiatryen_US
dc.subject.meshAgeden_US
dc.subject.meshCognition Disorders - Epidemiology - Etiologyen_US
dc.subject.meshDementia - Diagnosis - Epidemiology - Psychologyen_US
dc.subject.meshDepression - Epidemiology - Etiologyen_US
dc.subject.meshEpidemiologic Methodsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPsychiatric Status Rating Scalesen_US
dc.subject.meshResidence Characteristicsen_US
dc.subject.meshSex Factorsen_US
dc.subject.meshTime Factorsen_US
dc.titlePrevalence of clinically significant depressive symptoms in an epidemiologic sample of community-dwelling elders with milder forms of cognitive impairment in Hong Kong SARen_US
dc.typeArticleen_US
dc.identifier.emailChan, WC: waicchan@hku.hken_US
dc.identifier.authorityChan, WC=rp01687en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/gps.1948en_US
dc.identifier.pmid18041794-
dc.identifier.scopuseid_2-s2.0-46749146489en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-46749146489&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume23en_US
dc.identifier.issue6en_US
dc.identifier.spage611en_US
dc.identifier.epage617en_US
dc.identifier.isiWOS:000256859100009-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridChan, SSM=13409371900en_US
dc.identifier.scopusauthoridLam, LCW=7201984627en_US
dc.identifier.scopusauthoridTam, CWC=26021559000en_US
dc.identifier.scopusauthoridLui, VWC=9245605300en_US
dc.identifier.scopusauthoridChan, WC=16400525900en_US
dc.identifier.scopusauthoridWong, S=7404590811en_US
dc.identifier.scopusauthoridWong, A=36341876600en_US
dc.identifier.scopusauthoridTham, MK=16679910000en_US
dc.identifier.scopusauthoridHo, KS=7403581605en_US
dc.identifier.scopusauthoridChan, WM=7403918361en_US
dc.identifier.scopusauthoridChiu, HFK=24447976700en_US

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