File Download
 
 
Supplementary

Postgraduate Thesis: A cohort study on prematurity as an indicator of autistic symptom severity
  • Basic View
  • Metadata View
  • XML View
TitleA cohort study on prematurity as an indicator of autistic symptom severity
 
AuthorsChung, Weiyen.
钟慧元.
 
Issue Date2012
 
PublisherThe University of Hong Kong (Pokfulam, Hong Kong)
 
AbstractUsing the Autism Spectrum Disorder (ASD) database of the Department of Paediatric and Adolescent Medicine of The University of Hong Kong, a retrospective cohort study was carried out exploring the relationship between prematurity and symptom severity by using Childhood Autism Rating Scale (CARS). The premature group was found to have no significant difference in total CARS score as compared to the full term group, and no significant correlation was found between CARS score and gestational age [GA] (for children diagnosed or with suspected ASDs). Significantly higher numbers of the premature group (GA 37 weeks, N = 130) had multiple births, family history of ASDs or related disorders, pre/perinatal complications, as well as a significantly lower mean birth weight as compared to the full term group (GA > 37 weeks, N = 683). Mean total CARS score of very premature cases (M = 32.20, SD = 6.29) was found to be 2 points lower than mean total CARS score of those that were full term (GA > 37 weeks [M = 34.08, SD = 6.53]). However, the result was not statistically significant by unpaired t-test analysis. Therefore, results in this cohort show no relationship between prematurity and CARS score of children with ASDs, however further studies should be carried out in order to better validate existing findings.
 
DegreeMaster of Medical Sciences
 
SubjectAutism in children.
Premature infants.
Childhood Autism Rating Scale.
 
Dept/ProgramPaediatrics and Adolescent Medicine
 
DC FieldValue
dc.contributor.authorChung, Weiyen.
 
dc.contributor.author钟慧元.
 
dc.date.hkucongregation2012
 
dc.date.issued2012
 
dc.description.abstractUsing the Autism Spectrum Disorder (ASD) database of the Department of Paediatric and Adolescent Medicine of The University of Hong Kong, a retrospective cohort study was carried out exploring the relationship between prematurity and symptom severity by using Childhood Autism Rating Scale (CARS). The premature group was found to have no significant difference in total CARS score as compared to the full term group, and no significant correlation was found between CARS score and gestational age [GA] (for children diagnosed or with suspected ASDs). Significantly higher numbers of the premature group (GA 37 weeks, N = 130) had multiple births, family history of ASDs or related disorders, pre/perinatal complications, as well as a significantly lower mean birth weight as compared to the full term group (GA > 37 weeks, N = 683). Mean total CARS score of very premature cases (M = 32.20, SD = 6.29) was found to be 2 points lower than mean total CARS score of those that were full term (GA > 37 weeks [M = 34.08, SD = 6.53]). However, the result was not statistically significant by unpaired t-test analysis. Therefore, results in this cohort show no relationship between prematurity and CARS score of children with ASDs, however further studies should be carried out in order to better validate existing findings.
 
dc.description.naturepublished_or_final_version
 
dc.description.thesisdisciplinePaediatrics and Adolescent Medicine
 
dc.description.thesislevelmaster's
 
dc.description.thesisnameMaster of Medical Sciences
 
dc.identifier.hkulb4833373
 
dc.languageeng
 
dc.publisherThe University of Hong Kong (Pokfulam, Hong Kong)
 
dc.relation.ispartofHKU Theses Online (HKUTO)
 
dc.rightsThe author retains all proprietary rights, (such as patent rights) and the right to use in future works.
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
 
dc.source.urihttp://hub.hku.hk/bib/B48333736
 
dc.subject.lcshAutism in children.
 
dc.subject.lcshPremature infants.
 
dc.subject.lcshChildhood Autism Rating Scale.
 
dc.titleA cohort study on prematurity as an indicator of autistic symptom severity
 
dc.typePG_Thesis
 
<?xml encoding="utf-8" version="1.0"?>
<item><contributor.author>Chung, Weiyen.</contributor.author>
<contributor.author>&#38047;&#24935;&#20803;.</contributor.author>
<date.issued>2012</date.issued>
<description.abstract>&#65279;Using the Autism Spectrum Disorder (ASD) database of the Department of Paediatric and Adolescent Medicine of The University of Hong Kong, a retrospective cohort study was carried out exploring the relationship between prematurity and symptom severity by using Childhood Autism Rating Scale (CARS). The premature group was found to have no significant difference in total CARS score as compared to the full term group, and no significant correlation was found between CARS score and gestational age [GA] (for children diagnosed or with suspected ASDs). Significantly higher numbers of the premature group (GA &#61473;&#61472;37 weeks, N = 130) had multiple births, family history of ASDs or related disorders, pre/perinatal complications, as well as a significantly lower mean birth weight as compared to the full term group (GA &gt; 37 weeks, N = 683). Mean total CARS score of very premature cases (M = 32.20, SD = 6.29) was found to be 2 points lower than mean total CARS score of those that were full term (GA &gt; 37 weeks [M = 34.08, SD = 6.53]). However, the result was not statistically significant by unpaired t-test analysis. Therefore, results in this cohort show no relationship between prematurity and CARS score of children with ASDs, however further studies should be carried out in order to better validate existing findings.</description.abstract>
<language>eng</language>
<publisher>The University of Hong Kong (Pokfulam, Hong Kong)</publisher>
<relation.ispartof>HKU Theses Online (HKUTO)</relation.ispartof>
<rights>The author retains all proprietary rights, (such as patent rights) and the right to use in future works.</rights>
<rights>Creative Commons: Attribution 3.0 Hong Kong License</rights>
<source.uri>http://hub.hku.hk/bib/B48333736</source.uri>
<subject.lcsh>Autism in children.</subject.lcsh>
<subject.lcsh>Premature infants.</subject.lcsh>
<subject.lcsh>Childhood Autism Rating Scale.</subject.lcsh>
<title>A cohort study on prematurity as an indicator of autistic symptom severity</title>
<type>PG_Thesis</type>
<identifier.hkul>b4833373</identifier.hkul>
<description.thesisname>Master of Medical Sciences</description.thesisname>
<description.thesislevel>master&apos;s</description.thesislevel>
<description.thesisdiscipline>Paediatrics and Adolescent Medicine</description.thesisdiscipline>
<description.nature>published_or_final_version</description.nature>
<date.hkucongregation>2012</date.hkucongregation>
<bitstream.url>http://hub.hku.hk/bitstream/10722/173946/1/FullText.pdf</bitstream.url>
</item>