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undergraduate thesis: Distortion product otoacoustic emissions in patients with haemophilia

TitleDistortion product otoacoustic emissions in patients with haemophilia
Authors
Issue Date2010
PublisherThe University of Hong Kong (Pokfulam, Hong Kong)
Abstract
This study investigated the cochlear function of 13 haemophilic patients using distortion product otoacoustic emission (DPOAE) assessment techniques. Out of the 26 ears examined, a minority of them produced responses that were considered to be impaired. A positive correlation was found between clotting factor level and DPOAE amplitude, and DPOAE/ noise ratio at high frequencies (4, 6, 8 kHz). Clotting factor level, which is indicative of the severity of haemophilia, may be related to hearing status. It was also revealed that DPOAE amplitude and DPOAE/ noise ratio at low frequencies (1, 2, 3 kHz) were greater than those at high frequencies (4, 6, 8 kHz). Therefore the high-frequency cochlear region may be more sensitive to damage. Intracranial micro-haemorrhage in haemophilic individuals may be linked to an increased risk of cochlear damage. Further studies may use brain computed tomography scan to explore the possible link between intracranial micro-haemorrhage and hearing loss.
Description"A dissertation submitted in partial fulfillment of the requirements for the Bachelor of Science (Speech and Hearing Sciences), The University of Hong Kong, June 30, 2010."
DegreeBachelor of Science in Speech and Hearing Sciences
SubjectOtoacoustic emissions.
Hemophiliacs.
Dept/ProgramSpeech and Hearing Sciences
Persistent Identifierhttp://hdl.handle.net/10722/173719

 

DC FieldValueLanguage
dc.contributor.authorLeung, Hei-tinen_HK
dc.contributor.author梁曦田zh_HK
dc.date.accessioned2012-11-01T01:14:08Z-
dc.date.available2012-11-01T01:14:08Z-
dc.date.issued2010en_US
dc.identifier.urihttp://hdl.handle.net/10722/173719-
dc.description"A dissertation submitted in partial fulfillment of the requirements for the Bachelor of Science (Speech and Hearing Sciences), The University of Hong Kong, June 30, 2010."en_US
dc.descriptionIncludes bibliographical references (p. 22-24).en_US
dc.descriptionThesis (B.Sc)--University of Hong Kong, 2010.en_US
dc.description.abstractThis study investigated the cochlear function of 13 haemophilic patients using distortion product otoacoustic emission (DPOAE) assessment techniques. Out of the 26 ears examined, a minority of them produced responses that were considered to be impaired. A positive correlation was found between clotting factor level and DPOAE amplitude, and DPOAE/ noise ratio at high frequencies (4, 6, 8 kHz). Clotting factor level, which is indicative of the severity of haemophilia, may be related to hearing status. It was also revealed that DPOAE amplitude and DPOAE/ noise ratio at low frequencies (1, 2, 3 kHz) were greater than those at high frequencies (4, 6, 8 kHz). Therefore the high-frequency cochlear region may be more sensitive to damage. Intracranial micro-haemorrhage in haemophilic individuals may be linked to an increased risk of cochlear damage. Further studies may use brain computed tomography scan to explore the possible link between intracranial micro-haemorrhage and hearing loss.en_US
dc.languageengen_US
dc.publisherThe University of Hong Kong (Pokfulam, Hong Kong)en_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong Licenseen_US
dc.rightsThe author retains all proprietary rights, (such as patent rights) and the right to use in future works.en_US
dc.subject.lcshOtoacoustic emissions.en_US
dc.subject.lcshHemophiliacs.en_US
dc.titleDistortion product otoacoustic emissions in patients with haemophiliaen_HK
dc.typeUG_Thesisen_US
dc.identifier.hkulb4813170en_US
dc.description.thesisnameBachelor of Science in Speech and Hearing Sciencesen_US
dc.description.thesislevelbachelor'sen_US
dc.description.thesisdisciplineSpeech and Hearing Sciencesen_US
dc.description.naturepublished_or_final_versionen_US

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