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Article: Hemoglobin köln and pregnancy.

TitleHemoglobin köln and pregnancy.
Authors
Issue Date2008
PublisherCanadian Medical Association. The Journal's web site is located at http://sogc.medical.org/JOGC/index_e.shtml
Citation
Journal Of Obstetrics And Gynaecology Canada : Jogc = Journal D'obstétrique Et Gynécologie Du Canada : Jogc, 2008, v. 30 n. 10, p. 907-909 How to Cite?
AbstractBACKGROUND: Patients with hemoglobin Köln usually present with a mild hemolytic anemia characterized by reticulocytosis, splenomegaly, and elevated circulating bilirubin and lactate dehydrogenase levels. There have been no previous reports of whether these characteristics change during pregnancy and whether pregnancy provides any specific concerns for patients with hemoglobin Köln. CASE: A 36-year-old woman of Chinese origin with a twin pregnancy had an uneventful antenatal course except for the presence of thrombocytopenia that was not completely investigated. During elective repeat Caesarean section, it was noted that the woman had a low SpO2 on pulse oximetry despite a normal arterial oxygen tension from arterial blood gas measurement. Subsequent investigations identified the woman as a heterozygous carrier for hemoglobin Köln. CONCLUSION: Women with hemoglobin Köln who become pregnant require close monitoring of the maternal platelet count and an awareness of the falsely low SpO2 on pulse oximetry to ensure a favourable outcome.
Persistent Identifierhttp://hdl.handle.net/10722/173343
ISSN
2015 SCImago Journal Rankings: 0.788

 

DC FieldValueLanguage
dc.contributor.authorCheung, VYen_US
dc.contributor.authorSilverman, JAen_US
dc.date.accessioned2012-10-30T06:29:30Z-
dc.date.available2012-10-30T06:29:30Z-
dc.date.issued2008en_US
dc.identifier.citationJournal Of Obstetrics And Gynaecology Canada : Jogc = Journal D'obstétrique Et Gynécologie Du Canada : Jogc, 2008, v. 30 n. 10, p. 907-909en_US
dc.identifier.issn1701-2163en_US
dc.identifier.urihttp://hdl.handle.net/10722/173343-
dc.description.abstractBACKGROUND: Patients with hemoglobin Köln usually present with a mild hemolytic anemia characterized by reticulocytosis, splenomegaly, and elevated circulating bilirubin and lactate dehydrogenase levels. There have been no previous reports of whether these characteristics change during pregnancy and whether pregnancy provides any specific concerns for patients with hemoglobin Köln. CASE: A 36-year-old woman of Chinese origin with a twin pregnancy had an uneventful antenatal course except for the presence of thrombocytopenia that was not completely investigated. During elective repeat Caesarean section, it was noted that the woman had a low SpO2 on pulse oximetry despite a normal arterial oxygen tension from arterial blood gas measurement. Subsequent investigations identified the woman as a heterozygous carrier for hemoglobin Köln. CONCLUSION: Women with hemoglobin Köln who become pregnant require close monitoring of the maternal platelet count and an awareness of the falsely low SpO2 on pulse oximetry to ensure a favourable outcome.en_US
dc.languageengen_US
dc.publisherCanadian Medical Association. The Journal's web site is located at http://sogc.medical.org/JOGC/index_e.shtmlen_US
dc.relation.ispartofJournal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGCen_US
dc.subject.meshAdulten_US
dc.subject.meshCarrier Stateen_US
dc.subject.meshFemaleen_US
dc.subject.meshHemoglobins, Abnormal - Geneticsen_US
dc.subject.meshHeterozygoteen_US
dc.subject.meshHumansen_US
dc.subject.meshOximetryen_US
dc.subject.meshOxygen - Blooden_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Complications, Hematologic - Geneticsen_US
dc.subject.meshPregnancy, Multipleen_US
dc.subject.meshThrombocytopenia - Geneticsen_US
dc.subject.meshTwinsen_US
dc.titleHemoglobin köln and pregnancy.en_US
dc.typeArticleen_US
dc.identifier.emailCheung, VY:vytc@hku.hken_US
dc.identifier.authorityCheung, VY=rp01323en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid19038075-
dc.identifier.scopuseid_2-s2.0-59649104695en_US
dc.identifier.volume30en_US
dc.identifier.issue10en_US
dc.identifier.spage907en_US
dc.identifier.epage909en_US
dc.publisher.placeCanadaen_US
dc.identifier.scopusauthoridCheung, VY=7005439023en_US
dc.identifier.scopusauthoridSilverman, JA=16208825800en_US

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