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Article: Field strains of infectious bursal disease virus (IBDV) discovered in Hong Kong

TitleField strains of infectious bursal disease virus (IBDV) discovered in Hong Kong
Authors
Issue Date1996
PublisherFederation of American Societies for Experimental Biology. The Journal's web site is located at http://www.fasebj.org/
Citation
Faseb Journal, 1996, v. 10 n. 6, p. A1345 How to Cite?
AbstractInfectious bursal disease virus (IBDV) destroys the proliferating lymphocytes in the bursae of Fabricius of chicken. Chickens either die with acute infection or, if survive, become immunosu p pressed and therefore highly susceptible to other lethal diseases. Many strains have been isolated in different countries and they vary in the pathogenicity. Different strains are typed by the gene sequence of the major coat protein of the virus: VP2, which bears the neutralizing epitopes. VP2 is a polypeptide of approximated 40 kDa, which is derived from a precursor polyprotein. In this study, IBDV virus was isolated from bursae of local infected chicken collected by the Agriculture and Fisheries Department (AFD) of the Hong Kong Government, using a simplified procedure. By alignment of the gene sequences of all the published strains. oligonucleotides were designed to amplified the VP2 gene of the local strains by reverse transcriptase-polymerase chain reaction (RT-PCR). The sequences of the amplified VP2 gene indicated that two strains, including a highly virulent IBDV strain which was discovered in Japan in 1990 and an unpublished variant of IBDV, were prevalent in Hong Kong. Phylogenic tree showed that the unpublished variant is close to the highly virulent IBDV strains STC and 52/70.
Persistent Identifierhttp://hdl.handle.net/10722/173312
ISSN
2015 Impact Factor: 5.299
2015 SCImago Journal Rankings: 2.775

 

DC FieldValueLanguage
dc.contributor.authorLim, BLen_HK
dc.contributor.authorLaw, MSen_HK
dc.contributor.authorYeung, WSen_HK
dc.contributor.authorSim, LDen_HK
dc.contributor.authorWan, JMFen_HK
dc.contributor.authorLgung, FCCen_HK
dc.date.accessioned2012-10-30T06:29:14Z-
dc.date.available2012-10-30T06:29:14Z-
dc.date.issued1996en_HK
dc.identifier.citationFaseb Journal, 1996, v. 10 n. 6, p. A1345en_HK
dc.identifier.issn0892-6638en_HK
dc.identifier.urihttp://hdl.handle.net/10722/173312-
dc.description.abstractInfectious bursal disease virus (IBDV) destroys the proliferating lymphocytes in the bursae of Fabricius of chicken. Chickens either die with acute infection or, if survive, become immunosu p pressed and therefore highly susceptible to other lethal diseases. Many strains have been isolated in different countries and they vary in the pathogenicity. Different strains are typed by the gene sequence of the major coat protein of the virus: VP2, which bears the neutralizing epitopes. VP2 is a polypeptide of approximated 40 kDa, which is derived from a precursor polyprotein. In this study, IBDV virus was isolated from bursae of local infected chicken collected by the Agriculture and Fisheries Department (AFD) of the Hong Kong Government, using a simplified procedure. By alignment of the gene sequences of all the published strains. oligonucleotides were designed to amplified the VP2 gene of the local strains by reverse transcriptase-polymerase chain reaction (RT-PCR). The sequences of the amplified VP2 gene indicated that two strains, including a highly virulent IBDV strain which was discovered in Japan in 1990 and an unpublished variant of IBDV, were prevalent in Hong Kong. Phylogenic tree showed that the unpublished variant is close to the highly virulent IBDV strains STC and 52/70.en_HK
dc.languageengen_US
dc.publisherFederation of American Societies for Experimental Biology. The Journal's web site is located at http://www.fasebj.org/en_HK
dc.relation.ispartofFASEB Journalen_HK
dc.titleField strains of infectious bursal disease virus (IBDV) discovered in Hong Kongen_HK
dc.typeArticleen_HK
dc.identifier.emailLim, BL: bllim@hkucc.hku.hken_HK
dc.identifier.emailWan, JMF: jmfwan@hku.hken_HK
dc.identifier.authorityLim, BL=rp00744en_HK
dc.identifier.authorityWan, JMF=rp00798en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-33749131977en_HK
dc.identifier.volume10en_HK
dc.identifier.issue6en_HK
dc.identifier.spageA1345en_HK
dc.identifier.epageA1345en_HK
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLim, BL=7201983917en_HK
dc.identifier.scopusauthoridLaw, MS=14719699100en_HK
dc.identifier.scopusauthoridYeung, WS=55458229600en_HK
dc.identifier.scopusauthoridSim, LD=14720337200en_HK
dc.identifier.scopusauthoridWan, JMF=8930305000en_HK
dc.identifier.scopusauthoridLgung, FCC=14719870800en_HK

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