Article: Efficacy of preemptive analgesia for wound pain after laparoscopic operations in infertile women: A randomised, double-blind and placebo control study

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TitleEfficacy of preemptive analgesia for wound pain after laparoscopic operations in infertile women: A randomised, double-blind and placebo control study
AuthorsLam, KW1
Pun, TC1
Ng, EHY1
Wong, KS1
Issue Date2004
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/BJOG
CitationBjog: An International Journal Of Obstetrics And Gynaecology, 2004, v. 111 n. 4, p. 340-344 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1471-0528.2004.00083.x
AbstractObjective: To compare preemptive analgesia and preclosure analgesia in reducing wound pain after laparoscopic operation. Design: Randomised, double-blind and placebo control. Setting: University referral centre. Population: Infertile women undergoing diagnostic laparoscopy with or without additional procedures. Methods: One hundred and forty-four women were randomised to receive 10 mL of 1% lignocaine at the surgical sites before incision and 10 mL of normal saline before closure of incision (the preemptive group), saline before incision and lignocaine before closure of incision (the preclosure group) and saline at the surgical sites both before incision and closure of incision (the placebo group). Main outcome measures: Post-operative wound pain measured by linear visual analogue scale and amount of analgesic use. Results: The women in the preclosure group had significantly lower pain scores at 2, 4 and 24 hours than those in the placebo group, whereas the women in the preemptive group only showed significantly lower pain scores at 2 hours than the placebo group. The pain score at 24 hours in the preclosure group was significantly lower than that in the preemptive group. There was no significant difference in the postoperative analgesic requirement among the three groups. Conclusion: The preclosure analgesia is better than preemptive analgesia and no analgesia in reducing postoperative wound pain.
ISSN1470-0328
2011 Impact Factor: 3.407
2011 SCImago Journal Rankings: 0.268
DOIhttp://dx.doi.org/10.1111/j.1471-0528.2004.00083.x
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorLam, KW
dc.contributor.authorPun, TC
dc.contributor.authorNg, EHY
dc.contributor.authorWong, KS
dc.date.accessioned2012-10-30T06:29:04Z
dc.date.available2012-10-30T06:29:04Z
dc.date.issued2004
dc.description.abstractObjective: To compare preemptive analgesia and preclosure analgesia in reducing wound pain after laparoscopic operation. Design: Randomised, double-blind and placebo control. Setting: University referral centre. Population: Infertile women undergoing diagnostic laparoscopy with or without additional procedures. Methods: One hundred and forty-four women were randomised to receive 10 mL of 1% lignocaine at the surgical sites before incision and 10 mL of normal saline before closure of incision (the preemptive group), saline before incision and lignocaine before closure of incision (the preclosure group) and saline at the surgical sites both before incision and closure of incision (the placebo group). Main outcome measures: Post-operative wound pain measured by linear visual analogue scale and amount of analgesic use. Results: The women in the preclosure group had significantly lower pain scores at 2, 4 and 24 hours than those in the placebo group, whereas the women in the preemptive group only showed significantly lower pain scores at 2 hours than the placebo group. The pain score at 24 hours in the preclosure group was significantly lower than that in the preemptive group. There was no significant difference in the postoperative analgesic requirement among the three groups. Conclusion: The preclosure analgesia is better than preemptive analgesia and no analgesia in reducing postoperative wound pain.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationBjog: An International Journal Of Obstetrics And Gynaecology, 2004, v. 111 n. 4, p. 340-344 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1471-0528.2004.00083.x
dc.identifier.doihttp://dx.doi.org/10.1111/j.1471-0528.2004.00083.x
dc.identifier.epage344
dc.identifier.issn1470-0328
2011 Impact Factor: 3.407
2011 SCImago Journal Rankings: 0.268
dc.identifier.issue4
dc.identifier.pmid15008770
dc.identifier.scopuseid_2-s2.0-1842579455
dc.identifier.spage340
dc.identifier.urihttp://hdl.handle.net/10722/173283
dc.identifier.volume111
dc.languageeng
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/BJOG
dc.publisher.placeUnited Kingdom
dc.relation.ispartofBJOG: An International Journal of Obstetrics and Gynaecology
dc.relation.referencesReferences in Scopus
dc.subject.meshAdult
dc.subject.meshAnesthetics, Local - Administration & Dosage
dc.subject.meshDouble-Blind Method
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshInfertility, Female - Surgery
dc.subject.meshLaparoscopy - Adverse Effects
dc.subject.meshLidocaine - Administration & Dosage
dc.subject.meshPain, Postoperative - Drug Therapy
dc.subject.meshWound Healing - Physiology
dc.titleEfficacy of preemptive analgesia for wound pain after laparoscopic operations in infertile women: A randomised, double-blind and placebo control study
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong