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Article: Luteinizing hormone (LH) surge in patients using buserelin spray during ovarian stimulation for assisted reproduction

TitleLuteinizing hormone (LH) surge in patients using buserelin spray during ovarian stimulation for assisted reproduction
Authors
Issue Date1993
Citation
Asia-Oceania Journal Of Obstetrics And Gynaecology, 1993, v. 19 n. 2, p. 159-163 How to Cite?
AbstractThe incidence of luteinizing hormone surge was studied in patients who were downregulated with a short protocol of gonadotrophin releasing hormone agonist before ovarian stimulation for assisted reproduction. Buserelin nasal spray 100 μg was given 5 times daily from day 2 of the cycle, followed by ovarian stimulation with human menopausal gonadotrophin and follicle stimulating hormone from day 3 onwards. Of the 159 cycles studied, luteinizing hormone surge was detected in 9 cycles (5.7%). The occurrence of LH surge was usually (67%) but not always associated with a fall in serum oestradiol level before administration of human chorionic gonadotrophin. None of the patients developed luteinizing hormone surge after day 10. Even in patients without luteinizing hormone surge the serum luteinizing hormone levels on the day of administration of hCG were significantly higher than those on day 2 before administration of buserelin. It is concluded that a short protocol with intranasal buserelin 500 μg per day is inadequate to suppress endogenous luteinizing hormone surge.
Persistent Identifierhttp://hdl.handle.net/10722/173187
ISSN

 

DC FieldValueLanguage
dc.contributor.authorHo, PCen_US
dc.contributor.authorChan, YFen_US
dc.contributor.authorSo, WKen_US
dc.contributor.authorYeung, WSBen_US
dc.contributor.authorChan, STHen_US
dc.date.accessioned2012-10-30T06:28:24Z-
dc.date.available2012-10-30T06:28:24Z-
dc.date.issued1993en_US
dc.identifier.citationAsia-Oceania Journal Of Obstetrics And Gynaecology, 1993, v. 19 n. 2, p. 159-163en_US
dc.identifier.issn0389-2328en_US
dc.identifier.urihttp://hdl.handle.net/10722/173187-
dc.description.abstractThe incidence of luteinizing hormone surge was studied in patients who were downregulated with a short protocol of gonadotrophin releasing hormone agonist before ovarian stimulation for assisted reproduction. Buserelin nasal spray 100 μg was given 5 times daily from day 2 of the cycle, followed by ovarian stimulation with human menopausal gonadotrophin and follicle stimulating hormone from day 3 onwards. Of the 159 cycles studied, luteinizing hormone surge was detected in 9 cycles (5.7%). The occurrence of LH surge was usually (67%) but not always associated with a fall in serum oestradiol level before administration of human chorionic gonadotrophin. None of the patients developed luteinizing hormone surge after day 10. Even in patients without luteinizing hormone surge the serum luteinizing hormone levels on the day of administration of hCG were significantly higher than those on day 2 before administration of buserelin. It is concluded that a short protocol with intranasal buserelin 500 μg per day is inadequate to suppress endogenous luteinizing hormone surge.en_US
dc.languageengen_US
dc.relation.ispartofAsia-Oceania Journal of Obstetrics and Gynaecologyen_US
dc.subject.meshAdministration, Intranasalen_US
dc.subject.meshBuserelin - Administration & Dosageen_US
dc.subject.meshClinical Protocolsen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollicle Stimulating Hormone - Administration & Dosageen_US
dc.subject.meshHumansen_US
dc.subject.meshLuteinizing Hormone - Blooden_US
dc.subject.meshMenotropins - Administration & Dosageen_US
dc.subject.meshOvulation Induction - Methodsen_US
dc.titleLuteinizing hormone (LH) surge in patients using buserelin spray during ovarian stimulation for assisted reproductionen_US
dc.typeArticleen_US
dc.identifier.emailHo, PC:pcho@hku.hken_US
dc.identifier.emailYeung, WSB:wsbyeung@hkucc.hku.hken_US
dc.identifier.authorityHo, PC=rp00325en_US
dc.identifier.authorityYeung, WSB=rp00331en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid8379863-
dc.identifier.scopuseid_2-s2.0-0027204226en_US
dc.identifier.volume19en_US
dc.identifier.issue2en_US
dc.identifier.spage159en_US
dc.identifier.epage163en_US
dc.publisher.placeJapanen_US
dc.identifier.scopusauthoridHo, PC=7402211440en_US
dc.identifier.scopusauthoridChan, YF=7403676061en_US
dc.identifier.scopusauthoridSo, WK=36849240300en_US
dc.identifier.scopusauthoridYeung, WSB=7102370745en_US
dc.identifier.scopusauthoridChan, STH=24368283200en_US

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