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Article: Intrauterine insemination after ovarian stimulation as a treatment for subfertility because of subnormal semen: A prospective randomized controlled trial

TitleIntrauterine insemination after ovarian stimulation as a treatment for subfertility because of subnormal semen: A prospective randomized controlled trial
Authors
Issue Date1992
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/fertnstert
Citation
Fertility And Sterility, 1992, v. 58 n. 5, p. 995-999 How to Cite?
AbstractObjective: To determine whether intrauterine insemination (IUI) after ovarian stimulation with human menopausal gonadotropin (hMG) gives a better pregnancy rate (PR) than natural intercourse in couples with subfertility because of subnormal semen. Design: Prospective randomized controlled trial. Setting: University based subfertility clinic. Patients: Couples with subnormal semen as the only identifiable cause of subfertility. Interventions: In control cycles, the couples had natural intercourse. In IUI cycles, IUI was performed after ovarian stimulation with hMG and human chorionic gonadotropin. Main Outcome Measure: The clinical PRs and complications of IUI cycles and control cycles were compared. Results: There were six clinical pregnancies in the 42 IUI cycles, whereas there was no clinical pregnancy in the 42 control cycles. The clinical PR in IUI cycles (14.3% per cycle) was significantly higher than that in control cycles (0%). Six patients (14.3%) developed moderate degree of ovarian hyperstimulation syndrome in IUI cycles. Conclusion: Intrauterine insemination after ovarian stimulation with hMG is useful in treatment of subfertile couples with subnormal semen.
Persistent Identifierhttp://hdl.handle.net/10722/173176
ISSN
2015 Impact Factor: 4.426
2015 SCImago Journal Rankings: 2.156
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHo, PCen_US
dc.contributor.authorSo, WKen_US
dc.contributor.authorChan, YFen_US
dc.contributor.authorYeung, WSBen_US
dc.date.accessioned2012-10-30T06:28:21Z-
dc.date.available2012-10-30T06:28:21Z-
dc.date.issued1992en_US
dc.identifier.citationFertility And Sterility, 1992, v. 58 n. 5, p. 995-999en_US
dc.identifier.issn0015-0282en_US
dc.identifier.urihttp://hdl.handle.net/10722/173176-
dc.description.abstractObjective: To determine whether intrauterine insemination (IUI) after ovarian stimulation with human menopausal gonadotropin (hMG) gives a better pregnancy rate (PR) than natural intercourse in couples with subfertility because of subnormal semen. Design: Prospective randomized controlled trial. Setting: University based subfertility clinic. Patients: Couples with subnormal semen as the only identifiable cause of subfertility. Interventions: In control cycles, the couples had natural intercourse. In IUI cycles, IUI was performed after ovarian stimulation with hMG and human chorionic gonadotropin. Main Outcome Measure: The clinical PRs and complications of IUI cycles and control cycles were compared. Results: There were six clinical pregnancies in the 42 IUI cycles, whereas there was no clinical pregnancy in the 42 control cycles. The clinical PR in IUI cycles (14.3% per cycle) was significantly higher than that in control cycles (0%). Six patients (14.3%) developed moderate degree of ovarian hyperstimulation syndrome in IUI cycles. Conclusion: Intrauterine insemination after ovarian stimulation with hMG is useful in treatment of subfertile couples with subnormal semen.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/fertnsterten_US
dc.relation.ispartofFertility and Sterilityen_US
dc.subject.meshAdulten_US
dc.subject.meshChorionic Gonadotropin - Therapeutic Useen_US
dc.subject.meshEstradiol - Blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfertility, Male - Therapyen_US
dc.subject.meshInsemination, Artificial, Homologousen_US
dc.subject.meshMaleen_US
dc.subject.meshMenotropins - Therapeutic Useen_US
dc.subject.meshPregnancyen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshSemen - Physiologyen_US
dc.subject.meshSperm Counten_US
dc.subject.meshSperm Motilityen_US
dc.subject.meshSpermatozoa - Abnormalitiesen_US
dc.titleIntrauterine insemination after ovarian stimulation as a treatment for subfertility because of subnormal semen: A prospective randomized controlled trialen_US
dc.typeArticleen_US
dc.identifier.emailHo, PC:pcho@hku.hken_US
dc.identifier.emailYeung, WSB:wsbyeung@hkucc.hku.hken_US
dc.identifier.authorityHo, PC=rp00325en_US
dc.identifier.authorityYeung, WSB=rp00331en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid1426389-
dc.identifier.scopuseid_2-s2.0-0026453556en_US
dc.identifier.volume58en_US
dc.identifier.issue5en_US
dc.identifier.spage995en_US
dc.identifier.epage999en_US
dc.identifier.isiWOS:A1992JW69400022-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridHo, PC=7402211440en_US
dc.identifier.scopusauthoridSo, WK=36849240300en_US
dc.identifier.scopusauthoridChan, YF=7403676061en_US
dc.identifier.scopusauthoridYeung, WSB=7102370745en_US

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