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Article: Comparison of four different dosages of injectable bromocriptine retard for puerperal ablactation

TitleComparison of four different dosages of injectable bromocriptine retard for puerperal ablactation
Authors
Issue Date1990
Citation
European Journal Of Obstetrics Gynecology And Reproductive Biology, 1990, v. 34 n. 3, p. 223-228 How to Cite?
AbstractThe clinical efficacy, tolerance and effect on plasma prolactin levels of four different dosages of intramuscular bromocriptine retard were compared. 108 Chinese puerperas with a mean body weight of 58 kg, who chose not to breast-feed following vaginal delivery, were randomized into four equal groups. The patients in each group were given intramuscular bromocriptine retard: 20, 30, 40 or 50 mg. The injection was well tolerated by all, except for two patients who developed small haematomas at the site of the injection and 2 patients who complained of dizziness. Ablactation occurred in 100% of the patients in the 40 mg group, but was successful in only 92 and 91% of the patients in the 20 and 30 mg groups, respectively. There were two cases of suboptimal response in the 50 mg group, despite marked reduction in plasma prolactin levels. Both these patients had developed moderate breast engorgement before they received the injection. The difference in response among the four groups was not statistically significant. We recommend that the injection be given prior to the development of breast engorgement.
Persistent Identifierhttp://hdl.handle.net/10722/173162
ISSN
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorDuthie, SJen_US
dc.contributor.authorLi FukHim, Den_US
dc.contributor.authorHangSeng Fang, Aen_US
dc.contributor.authorO'hoy, KMen_US
dc.contributor.authorPakChung, Hen_US
dc.date.accessioned2012-10-30T06:28:16Z-
dc.date.available2012-10-30T06:28:16Z-
dc.date.issued1990en_US
dc.identifier.citationEuropean Journal Of Obstetrics Gynecology And Reproductive Biology, 1990, v. 34 n. 3, p. 223-228en_US
dc.identifier.issn0028-2243en_US
dc.identifier.urihttp://hdl.handle.net/10722/173162-
dc.description.abstractThe clinical efficacy, tolerance and effect on plasma prolactin levels of four different dosages of intramuscular bromocriptine retard were compared. 108 Chinese puerperas with a mean body weight of 58 kg, who chose not to breast-feed following vaginal delivery, were randomized into four equal groups. The patients in each group were given intramuscular bromocriptine retard: 20, 30, 40 or 50 mg. The injection was well tolerated by all, except for two patients who developed small haematomas at the site of the injection and 2 patients who complained of dizziness. Ablactation occurred in 100% of the patients in the 40 mg group, but was successful in only 92 and 91% of the patients in the 20 and 30 mg groups, respectively. There were two cases of suboptimal response in the 50 mg group, despite marked reduction in plasma prolactin levels. Both these patients had developed moderate breast engorgement before they received the injection. The difference in response among the four groups was not statistically significant. We recommend that the injection be given prior to the development of breast engorgement.en_US
dc.languageengen_US
dc.relation.ispartofEuropean Journal of Obstetrics Gynecology and Reproductive Biologyen_US
dc.subject.meshBody Weighten_US
dc.subject.meshBromocriptine - Administration & Dosageen_US
dc.subject.meshDelayed-Action Preparationsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHong Kong - Ethnologyen_US
dc.subject.meshHumansen_US
dc.subject.meshInjections, Intramuscularen_US
dc.subject.meshLactation - Drug Effectsen_US
dc.subject.meshPostpartum Perioden_US
dc.subject.meshPregnancyen_US
dc.subject.meshProlactin - Blooden_US
dc.subject.meshTime Factorsen_US
dc.titleComparison of four different dosages of injectable bromocriptine retard for puerperal ablactationen_US
dc.typeArticleen_US
dc.identifier.emailPakChung, H:pcho@hku.hken_US
dc.identifier.authorityPakChung, H=rp00325en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0028-2243(90)90075-C-
dc.identifier.pmid2311809-
dc.identifier.scopuseid_2-s2.0-0025156983en_US
dc.identifier.volume34en_US
dc.identifier.issue3en_US
dc.identifier.spage223en_US
dc.identifier.epage228en_US
dc.identifier.isiWOS:A1990CP55500005-
dc.identifier.scopusauthoridDuthie, SJ=7004271794en_US
dc.identifier.scopusauthoridLi FukHim, D=6504622208en_US
dc.identifier.scopusauthoridHangSeng Fang, A=6505571153en_US
dc.identifier.scopusauthoridO'Hoy, KM=6602326255en_US
dc.identifier.scopusauthoridPakChung, H=7402211440en_US

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