Bio-psycho-social aspects of gonadal dysgenesis

Abstract

Gonadal dysgenesis is the commonest cause of primary amenorrhea. Women with such a disease syndrome feel physically healthy but they lack the two bodily functions which are exclusively feminine: menstruation and child-bearing. The present study of 86 Chinese women with gonadal dysgenesis showed that their congenital abnormalities did not interfere with their school and work achievement, but these women were found to be socially inhibited. Only 21 women (24.4%) were ever married and only 10 other women (6.5%) had formed heterosexual relationships. The major deterrent factor was infertility. Whilst hormonal therapy made these women feel better because of the induction of menstruation and breast development, clinic visits to obtain such hormones were upsetting in 27 (31.4%) of them. Observations in a 2-year period did not show that these women were able to overcome their psychosocial difficulties, despite support and encouragement. Possible intervention strategies are discussed.