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Article: Further evaluation of first morning urinary oestrogen in monitoring gonadotrophin therapy

TitleFurther evaluation of first morning urinary oestrogen in monitoring gonadotrophin therapy
Authors
Issue Date1988
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ANZJOG
Citation
Australian And New Zealand Journal Of Obstetrics And Gynaecology, 1988, v. 28 n. 2, p. 141-143 How to Cite?
AbstractEfficient gonadotrophin therapy requires both biochemical and ultrasonic measurements of ovarian response. Biochemical monitoring can take the form of measurement of plasma oestradiol levels or urinary oestrogen excretion. Levels of first morning urinary oestrogen to creatinine ratio have been shown to correlate well with 24-hour total urinary oestrogen excretion. Such urine collection is not cumbersome and is less invasive than daily venepuncture. Eighty gonadotrophin treatment cycles were evaluated by first morning urinary oestrogen to creatinine ratio and ultrasound scanning of follicles. Analysis confirmed that the ratio correlated significantly both with plasma oestradiol and 24-hour urinary oestrogen levels. The administration of the ovulating dose of human chorionic gonadotrophin depended primarily on ultrasonic demonstration of the presence of mature follicles in the ovaries. There was no increased incidence of multiple gestation or hyperstimulation syndrome in 135 treatment cycles. It is concluded that first morning urinary oestrogen to creatinine ratio is a convenient and cheap method of efficient biochemical monitoring of ovarian response to gonadotrophin therapy.
Persistent Identifierhttp://hdl.handle.net/10722/173134
ISSN
2015 Impact Factor: 1.738
2015 SCImago Journal Rankings: 0.814
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorTang, GWKen_US
dc.contributor.authorChan, SYWen_US
dc.date.accessioned2012-10-30T06:28:07Z-
dc.date.available2012-10-30T06:28:07Z-
dc.date.issued1988en_US
dc.identifier.citationAustralian And New Zealand Journal Of Obstetrics And Gynaecology, 1988, v. 28 n. 2, p. 141-143en_US
dc.identifier.issn0004-8666en_US
dc.identifier.urihttp://hdl.handle.net/10722/173134-
dc.description.abstractEfficient gonadotrophin therapy requires both biochemical and ultrasonic measurements of ovarian response. Biochemical monitoring can take the form of measurement of plasma oestradiol levels or urinary oestrogen excretion. Levels of first morning urinary oestrogen to creatinine ratio have been shown to correlate well with 24-hour total urinary oestrogen excretion. Such urine collection is not cumbersome and is less invasive than daily venepuncture. Eighty gonadotrophin treatment cycles were evaluated by first morning urinary oestrogen to creatinine ratio and ultrasound scanning of follicles. Analysis confirmed that the ratio correlated significantly both with plasma oestradiol and 24-hour urinary oestrogen levels. The administration of the ovulating dose of human chorionic gonadotrophin depended primarily on ultrasonic demonstration of the presence of mature follicles in the ovaries. There was no increased incidence of multiple gestation or hyperstimulation syndrome in 135 treatment cycles. It is concluded that first morning urinary oestrogen to creatinine ratio is a convenient and cheap method of efficient biochemical monitoring of ovarian response to gonadotrophin therapy.en_US
dc.languageengen_US
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ANZJOGen_US
dc.relation.ispartofAustralian and New Zealand Journal of Obstetrics and Gynaecologyen_US
dc.subject.meshChorionic Gonadotropin - Administration & Dosageen_US
dc.subject.meshCreatinine - Urineen_US
dc.subject.meshEstrogens - Blood - Urineen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMenotropins - Administration & Dosageen_US
dc.subject.meshMonitoring, Physiologic - Methodsen_US
dc.subject.meshOvulation Induction - Methodsen_US
dc.subject.meshUltrasonographyen_US
dc.titleFurther evaluation of first morning urinary oestrogen in monitoring gonadotrophin therapyen_US
dc.typeArticleen_US
dc.identifier.emailTang, GWK:gwktang@hkucc.hku.hken_US
dc.identifier.authorityTang, GWK=rp00328en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1479-828X.1988.tb01644.x-
dc.identifier.pmid3147651-
dc.identifier.scopuseid_2-s2.0-0023926210en_US
dc.identifier.volume28en_US
dc.identifier.issue2en_US
dc.identifier.spage141en_US
dc.identifier.epage143en_US
dc.identifier.isiWOS:A1988P287500016-
dc.publisher.placeAustraliaen_US
dc.identifier.scopusauthoridTang, GWK=7401633864en_US
dc.identifier.scopusauthoridChan, SYW=7404255960en_US

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