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Article: Plasma prolactin, progesterone, estradiol, and human chorionic gonadotropin in complete and partial moles before and after evacuation

TitlePlasma prolactin, progesterone, estradiol, and human chorionic gonadotropin in complete and partial moles before and after evacuation
Authors
Issue Date1986
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.greenjournal.org
Citation
Obstetrics And Gynecology, 1986, v. 67 n. 1, p. 99-106 How to Cite?
AbstractPlasma prolactin, progesterone, and 17β-estradiol were measured by radioimmunoassay in 58 patients with complete moles, 17 patients with partial moles, and the same number of maturity-matched pregnant control subjects. In both complete and partial moles in the first trimester, the pre-evacuation plasma levels of these hormones were similar to those of pregnant control subjects, but in the second trimester they were all significantly lower than those of pregnant controls. There was no significant difference in the regression patterns of these hormones between complete and partial moles, but the serum β-subunit of human chorionic gonadotropin (βhCG) was higher in complete moles. Patients who subsequently developed persistent gestational trophoblastic tumors had higher plasma estradiol, prolactin, and serum βhCG than those without persistent gestational trophoblastic tumors both before and after evacuation, but the difference in plasma estradiol and prolactin disappeared by nine weeks after evacuation. The levels of these hormones in patients with theca-lutein cysts were higher than those without theca-lutein cysts in the first few weeks after evacuation. Plasma estradiol, progesterone, and prolactin returned to normal nonpregnant levels before serum βhCG, and they were not useful as tumor markers.
Persistent Identifierhttp://hdl.handle.net/10722/173108
ISSN
2015 Impact Factor: 5.656
2015 SCImago Journal Rankings: 2.899
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHo, PCen_US
dc.contributor.authorWong, LCen_US
dc.contributor.authorMa, HKen_US
dc.date.accessioned2012-10-30T06:27:58Z-
dc.date.available2012-10-30T06:27:58Z-
dc.date.issued1986en_US
dc.identifier.citationObstetrics And Gynecology, 1986, v. 67 n. 1, p. 99-106en_US
dc.identifier.issn0029-7844en_US
dc.identifier.urihttp://hdl.handle.net/10722/173108-
dc.description.abstractPlasma prolactin, progesterone, and 17β-estradiol were measured by radioimmunoassay in 58 patients with complete moles, 17 patients with partial moles, and the same number of maturity-matched pregnant control subjects. In both complete and partial moles in the first trimester, the pre-evacuation plasma levels of these hormones were similar to those of pregnant control subjects, but in the second trimester they were all significantly lower than those of pregnant controls. There was no significant difference in the regression patterns of these hormones between complete and partial moles, but the serum β-subunit of human chorionic gonadotropin (βhCG) was higher in complete moles. Patients who subsequently developed persistent gestational trophoblastic tumors had higher plasma estradiol, prolactin, and serum βhCG than those without persistent gestational trophoblastic tumors both before and after evacuation, but the difference in plasma estradiol and prolactin disappeared by nine weeks after evacuation. The levels of these hormones in patients with theca-lutein cysts were higher than those without theca-lutein cysts in the first few weeks after evacuation. Plasma estradiol, progesterone, and prolactin returned to normal nonpregnant levels before serum βhCG, and they were not useful as tumor markers.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.greenjournal.orgen_US
dc.relation.ispartofObstetrics and Gynecologyen_US
dc.subject.meshAdulten_US
dc.subject.meshChorionic Gonadotropin - Blooden_US
dc.subject.meshDilatation And Curettageen_US
dc.subject.meshEstradiol - Blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHydatidiform Mole - Blood - Surgeryen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Proteins - Blooden_US
dc.subject.meshProgesterone - Blooden_US
dc.subject.meshProlactin - Blooden_US
dc.subject.meshTime Factorsen_US
dc.subject.meshUterine Neoplasms - Blood - Surgeryen_US
dc.subject.meshVacuum Curettageen_US
dc.titlePlasma prolactin, progesterone, estradiol, and human chorionic gonadotropin in complete and partial moles before and after evacuationen_US
dc.typeArticleen_US
dc.identifier.emailHo, PC:pcho@hku.hken_US
dc.identifier.authorityHo, PC=rp00325en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid3940346-
dc.identifier.scopuseid_2-s2.0-0022630594en_US
dc.identifier.volume67en_US
dc.identifier.issue1en_US
dc.identifier.spage99en_US
dc.identifier.epage106en_US
dc.identifier.isiWOS:A1986AWU2300020-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridHo, PC=7402211440en_US
dc.identifier.scopusauthoridWong, LC=7402092003en_US
dc.identifier.scopusauthoridMa, HK=7403095603en_US

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