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Article: T-cell subsets and natural killer cell activity in patients with gestational trophoblastic neoplasia

TitleT-cell subsets and natural killer cell activity in patients with gestational trophoblastic neoplasia
Authors
Issue Date1986
PublisherMosby, Inc. The Journal's web site is located at http://www.elsevier.com/locate/ajog
Citation
American Journal Of Obstetrics And Gynecology, 1986, v. 155 n. 2, p. 330-334 How to Cite?
AbstractLymphocyte counts, T-cell counts, B-cell counts, helper T-cell counts, and suppressor-cytotoxic T-cell counts were performed in 28 patients with gestational trophoblastic neoplasia and 38 normal control subjects. Natural killer cell activity was also assayed in 30 patients and 30 control subjects. The percentage and count of lymphocytes and the absolute counts (but not the percentages) of T cells, helper T cells, and suppressor-cytotoxic T cells in patients with gestational trophoblastic neoplasia were significantly lower than those of normal control subjects. In high-risk patients with gestational trophoblastic neoplasia, there was also a significant reduction of the helper T cell to suppressor-cytotoxic T-cell ratio in comparison with that in normal control subjects. There was no significant difference in the B-cell counts or natural killer cell activity. The measurement of these parameters was not useful in predicting the response to chemotherapy.
Persistent Identifierhttp://hdl.handle.net/10722/173104
ISSN
2015 Impact Factor: 4.681
2015 SCImago Journal Rankings: 2.255
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHo, PCen_US
dc.contributor.authorLawton, JWMen_US
dc.contributor.authorWong, LCen_US
dc.contributor.authorMa, HKen_US
dc.date.accessioned2012-10-30T06:27:57Z-
dc.date.available2012-10-30T06:27:57Z-
dc.date.issued1986en_US
dc.identifier.citationAmerican Journal Of Obstetrics And Gynecology, 1986, v. 155 n. 2, p. 330-334en_US
dc.identifier.issn0002-9378en_US
dc.identifier.urihttp://hdl.handle.net/10722/173104-
dc.description.abstractLymphocyte counts, T-cell counts, B-cell counts, helper T-cell counts, and suppressor-cytotoxic T-cell counts were performed in 28 patients with gestational trophoblastic neoplasia and 38 normal control subjects. Natural killer cell activity was also assayed in 30 patients and 30 control subjects. The percentage and count of lymphocytes and the absolute counts (but not the percentages) of T cells, helper T cells, and suppressor-cytotoxic T cells in patients with gestational trophoblastic neoplasia were significantly lower than those of normal control subjects. In high-risk patients with gestational trophoblastic neoplasia, there was also a significant reduction of the helper T cell to suppressor-cytotoxic T-cell ratio in comparison with that in normal control subjects. There was no significant difference in the B-cell counts or natural killer cell activity. The measurement of these parameters was not useful in predicting the response to chemotherapy.en_US
dc.languageengen_US
dc.publisherMosby, Inc. The Journal's web site is located at http://www.elsevier.com/locate/ajogen_US
dc.relation.ispartofAmerican Journal of Obstetrics and Gynecologyen_US
dc.subject.meshAdulten_US
dc.subject.meshAntibodies, Monoclonal - Diagnostic Useen_US
dc.subject.meshB-Lymphocytes - Immunologyen_US
dc.subject.meshChoriocarcinoma - Immunologyen_US
dc.subject.meshCytotoxicity Tests, Immunologicen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshKiller Cells, Natural - Immunologyen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPregnancyen_US
dc.subject.meshT-Lymphocytes - Immunologyen_US
dc.subject.meshTrophoblastic Neoplasms - Immunologyen_US
dc.subject.meshUterine Neoplasms - Immunologyen_US
dc.titleT-cell subsets and natural killer cell activity in patients with gestational trophoblastic neoplasiaen_US
dc.typeArticleen_US
dc.identifier.emailHo, PC:pcho@hku.hken_US
dc.identifier.authorityHo, PC=rp00325en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0002-9378(86)90820-3-
dc.identifier.pmid3017112-
dc.identifier.scopuseid_2-s2.0-0022502820en_US
dc.identifier.volume155en_US
dc.identifier.issue2en_US
dc.identifier.spage330en_US
dc.identifier.epage334en_US
dc.identifier.isiWOS:A1986D669100022-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridHo, PC=7402211440en_US
dc.identifier.scopusauthoridLawton, JWM=7102180792en_US
dc.identifier.scopusauthoridWong, LC=7402092003en_US
dc.identifier.scopusauthoridMa, HK=7403095603en_US

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