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Article: Pre-operative cervical dilatation in termination of first trimester pregnancies using 16, 16-dimethyl-trans-Δ2 PGE1 methyl ester vaginal pessaries

TitlePre-operative cervical dilatation in termination of first trimester pregnancies using 16, 16-dimethyl-trans-Δ2 PGE1 methyl ester vaginal pessaries
Authors
Issue Date1983
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/contraception
Citation
Contraception, 1983, v. 27 n. 4, p. 339-346 How to Cite?
AbstractThe effect of a prostaglandin E1 analogue on the cervix prior to termination of first trimester pregnancy was studied in a double-blind placebo-controlled trial with 70 primigravid and 125 multigravid patients in the Hong Kong University Gynaecological Unit. One mg of 16, 16-dimethyl-trans-Δ2-prostaglandin E1 methyl ester (ONO 802) in the form of vaginal pessary was inserted 3 hours before vacuum aspiration. The cervical dilatation in patients receiving ONO 802 pessaries was significantly greater than that in patients who received no treatment or placebo pessaries but the difference in dilatation between patients who received no treatment or placebo was not significant. The blood loss during operation in patients receiving ONO 802 pessaries was also significantly less than that in patients receiving placebo pessaries. The side effects due to ONO 802 pessaries were mild and infrequent.
Persistent Identifierhttp://hdl.handle.net/10722/173066
ISSN
2015 Impact Factor: 2.788
2015 SCImago Journal Rankings: 1.557
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHo, PCen_US
dc.contributor.authorLiang, STen_US
dc.contributor.authorTang, GWKen_US
dc.contributor.authorMa, HKen_US
dc.date.accessioned2012-10-30T06:27:47Z-
dc.date.available2012-10-30T06:27:47Z-
dc.date.issued1983en_US
dc.identifier.citationContraception, 1983, v. 27 n. 4, p. 339-346en_US
dc.identifier.issn0010-7824en_US
dc.identifier.urihttp://hdl.handle.net/10722/173066-
dc.description.abstractThe effect of a prostaglandin E1 analogue on the cervix prior to termination of first trimester pregnancy was studied in a double-blind placebo-controlled trial with 70 primigravid and 125 multigravid patients in the Hong Kong University Gynaecological Unit. One mg of 16, 16-dimethyl-trans-Δ2-prostaglandin E1 methyl ester (ONO 802) in the form of vaginal pessary was inserted 3 hours before vacuum aspiration. The cervical dilatation in patients receiving ONO 802 pessaries was significantly greater than that in patients who received no treatment or placebo pessaries but the difference in dilatation between patients who received no treatment or placebo was not significant. The blood loss during operation in patients receiving ONO 802 pessaries was also significantly less than that in patients receiving placebo pessaries. The side effects due to ONO 802 pessaries were mild and infrequent.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/contraceptionen_US
dc.relation.ispartofContraceptionen_US
dc.subject.meshAbortifacient Agents - Pharmacologyen_US
dc.subject.meshAbortifacient Agents, Nonsteroidal - Pharmacologyen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAlprostadil - Analogs & Derivativesen_US
dc.subject.meshCervix Uteri - Drug Effectsen_US
dc.subject.meshDilatation - Methodsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Trimester, Firsten_US
dc.subject.meshProstaglandins E, Synthetic - Adverse Effects - Pharmacologyen_US
dc.subject.meshSuppositoriesen_US
dc.subject.meshVaginaen_US
dc.titlePre-operative cervical dilatation in termination of first trimester pregnancies using 16, 16-dimethyl-trans-Δ2 PGE1 methyl ester vaginal pessariesen_US
dc.typeArticleen_US
dc.identifier.emailHo, PC:pcho@hku.hken_US
dc.identifier.emailTang, GWK:gwktang@hkucc.hku.hken_US
dc.identifier.authorityHo, PC=rp00325en_US
dc.identifier.authorityTang, GWK=rp00328en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0010-7824(83)80014-6-
dc.identifier.pmid6851564-
dc.identifier.scopuseid_2-s2.0-0020527092en_US
dc.identifier.volume27en_US
dc.identifier.issue4en_US
dc.identifier.spage339en_US
dc.identifier.epage346en_US
dc.identifier.isiWOS:A1983QN79600002-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridHo, PC=7402211440en_US
dc.identifier.scopusauthoridLiang, ST=7402146735en_US
dc.identifier.scopusauthoridTang, GWK=7401633864en_US
dc.identifier.scopusauthoridMa, HK=7403095603en_US

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