File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: New tools for functional genomic analysis

TitleNew tools for functional genomic analysis
Authors
Issue Date2009
PublisherElsevier Ltd, Trends Journals. The Journal's web site is located at http://www.elsevier.com/locate/drugdiscov
Citation
Drug Discovery Today, 2009, v. 14 n. 15-16, p. 754-760 How to Cite?
AbstractFor the past decade, the development of genomic technology has revolutionized modern biological research and drug discovery. Functional genomic analyses enable biologists to perform analysis of genetic events on a global scale and they have been widely used in gene discovery, biomarker determination, disease classification, and drug target identification. In this article, we provide an overview of the current and emerging tools involved in genomic studies, including expression arrays, microRNA arrays, array CGH, ChIP-on-chip, methylation arrays, mutation analysis, genome-wide association studies, proteomic analysis, integrated functional genomic analysis and related bioinformatic and biostatistical analyses. Using human liver cancer as an example, we provide further information of how these genomic approaches can be applied in cancer research. © 2009 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/172991
ISSN
2015 Impact Factor: 5.625
2015 SCImago Journal Rankings: 2.084
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChen, Xen_US
dc.contributor.authorJorgenson, Een_US
dc.contributor.authorCheung, STen_US
dc.date.accessioned2012-10-30T06:26:15Z-
dc.date.available2012-10-30T06:26:15Z-
dc.date.issued2009en_US
dc.identifier.citationDrug Discovery Today, 2009, v. 14 n. 15-16, p. 754-760en_US
dc.identifier.issn1359-6446en_US
dc.identifier.urihttp://hdl.handle.net/10722/172991-
dc.description.abstractFor the past decade, the development of genomic technology has revolutionized modern biological research and drug discovery. Functional genomic analyses enable biologists to perform analysis of genetic events on a global scale and they have been widely used in gene discovery, biomarker determination, disease classification, and drug target identification. In this article, we provide an overview of the current and emerging tools involved in genomic studies, including expression arrays, microRNA arrays, array CGH, ChIP-on-chip, methylation arrays, mutation analysis, genome-wide association studies, proteomic analysis, integrated functional genomic analysis and related bioinformatic and biostatistical analyses. Using human liver cancer as an example, we provide further information of how these genomic approaches can be applied in cancer research. © 2009 Elsevier Ltd. All rights reserved.en_US
dc.languageengen_US
dc.publisherElsevier Ltd, Trends Journals. The Journal's web site is located at http://www.elsevier.com/locate/drugdiscoven_US
dc.relation.ispartofDrug Discovery Todayen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBiological Markers - Analysisen_US
dc.subject.meshBiomedical Research - Methodsen_US
dc.subject.meshDrug Delivery Systemsen_US
dc.subject.meshDrug Discovery - Methodsen_US
dc.subject.meshGenomics - Methodsen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver Neoplasms - Geneticsen_US
dc.subject.meshMicrornas - Metabolismen_US
dc.subject.meshOligonucleotide Array Sequence Analysis - Methodsen_US
dc.subject.meshProteomics - Methodsen_US
dc.titleNew tools for functional genomic analysisen_US
dc.typeArticleen_US
dc.identifier.emailCheung, ST: stcheung@hkucc.hku.hken_US
dc.identifier.authorityCheung, ST=rp00457en_US
dc.description.naturelink_to_OA_fulltexten_US
dc.identifier.doi10.1016/j.drudis.2009.05.005en_US
dc.identifier.pmid19477290-
dc.identifier.scopuseid_2-s2.0-67651233521en_US
dc.identifier.hkuros164795-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-67651233521&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume14en_US
dc.identifier.issue15-16en_US
dc.identifier.spage754en_US
dc.identifier.epage760en_US
dc.identifier.isiWOS:000269243000005-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridChen, X=8978110800en_US
dc.identifier.scopusauthoridJorgenson, E=6602739187en_US
dc.identifier.scopusauthoridCheung, ST=7202473497en_US
dc.identifier.citeulike4745321-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats