File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Gastric cancer associated glycoprotein with bisection GlcNAc structure

TitleGastric cancer associated glycoprotein with bisection GlcNAc structure
Authors
Issue Date1997
Citation
Journal Of Tumor Marker Oncology, 1997, v. 12 n. 1, p. 13-19 How to Cite?
AbstractIn this report, the clinical significance of gastrointestinal cancer associated glycoprotein with bisection GlcNAc structure was investigated by affinity assay and immunobiochemical methods. The results of 51 Cr-release assay suggested that this glycoprotein could inhibit the cytotoxicity of NK and LAK cells for their target cells. The results of enzyme-linked immunoassay suggested that the expression of gastric cancer associated glycoproteins with bisection GlcNAc oligosaccharides structure was higher in serum of the patient with gastrointestinal cancer than that in serum of the patient with benign disease. (p<0.001). The sensitivity of this analysis procedure were 59.9% (191/320) for diagnosis of gastric cancer and 64.1% (100/156) for diagnosis of colorectal cancer. Its speciality was 91.8% for diagnosis of tumor. The results also indicated that the level of gastric cancer oligosaccharides in serum related to the differentiation type of cancer and the immunological activity of LAK cells. The present study provided a new approach for research on tumor marker and glycosylation associated with gastro-intestinal cancer.
Persistent Identifierhttp://hdl.handle.net/10722/172929
ISSN
2001 Impact Factor: 0.163
2004 SCImago Journal Rankings: 0.114
References

 

DC FieldValueLanguage
dc.contributor.authorZhang, JRen_US
dc.contributor.authorFan, STen_US
dc.contributor.authorYu, WCen_US
dc.date.accessioned2012-10-30T06:25:51Z-
dc.date.available2012-10-30T06:25:51Z-
dc.date.issued1997en_US
dc.identifier.citationJournal Of Tumor Marker Oncology, 1997, v. 12 n. 1, p. 13-19en_US
dc.identifier.issn0886-3849en_US
dc.identifier.urihttp://hdl.handle.net/10722/172929-
dc.description.abstractIn this report, the clinical significance of gastrointestinal cancer associated glycoprotein with bisection GlcNAc structure was investigated by affinity assay and immunobiochemical methods. The results of 51 Cr-release assay suggested that this glycoprotein could inhibit the cytotoxicity of NK and LAK cells for their target cells. The results of enzyme-linked immunoassay suggested that the expression of gastric cancer associated glycoproteins with bisection GlcNAc oligosaccharides structure was higher in serum of the patient with gastrointestinal cancer than that in serum of the patient with benign disease. (p<0.001). The sensitivity of this analysis procedure were 59.9% (191/320) for diagnosis of gastric cancer and 64.1% (100/156) for diagnosis of colorectal cancer. Its speciality was 91.8% for diagnosis of tumor. The results also indicated that the level of gastric cancer oligosaccharides in serum related to the differentiation type of cancer and the immunological activity of LAK cells. The present study provided a new approach for research on tumor marker and glycosylation associated with gastro-intestinal cancer.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Tumor Marker Oncologyen_US
dc.titleGastric cancer associated glycoprotein with bisection GlcNAc structureen_US
dc.typeArticleen_US
dc.identifier.emailFan, ST: stfan@hku.hken_US
dc.identifier.authorityFan, ST=rp00355en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-33750064267en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33750064267&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume12en_US
dc.identifier.issue1en_US
dc.identifier.spage13en_US
dc.identifier.epage19en_US
dc.publisher.placeAustriaen_US
dc.identifier.scopusauthoridZhang, JR=36011268900en_US
dc.identifier.scopusauthoridFan, ST=7402678224en_US
dc.identifier.scopusauthoridYu, WC=37022285400en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats