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Article: Prognostic factors of clinically stage I and II oral tongue carcinoma - A comparative study of stage, thickness, shape, growth pattern, invasive front malignancy grading, Martinez-Gimeno score, and pathologic features

TitlePrognostic factors of clinically stage I and II oral tongue carcinoma - A comparative study of stage, thickness, shape, growth pattern, invasive front malignancy grading, Martinez-Gimeno score, and pathologic features
Authors
Issue Date2002
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137
Citation
Head And Neck, 2002, v. 24 n. 6, p. 513-520 How to Cite?
AbstractPurpose. This study aims at evaluation of the different prognostic models, including stage, tumor thickness, shape, malignancy grading of tumor invasive front, Martinez-Gimeno score, and pathologic features in the prediction of subclinical nodal metastasis, local recurrence, and survival of early T1 and T2 oral tongue squamous cell carcinoma. The results will have important implication for the management of patients. Patients and Methods. Seventy-two clinically T1 and T2 glossectomy specimens of oral tongue carcinoma were serially sectioned in 3-mm thickness for the evaluation of various pathologic features. The prognostic value in the prediction of subclinical nodal metastasis, local recurrence, and survival of different models were compared. Results. Among all the tumor parameters and predictive models being evaluated, tumor thickness was the only significant factor that had significant predictive value for subclinical nodal metastasis, local recurrence, and survival. With the use of 3-mm and 9-mm division, tumor of up to 3-mm thickness has 8% subclinical nodal metastasis, 0% local recurrence, and 100% 5-year actuarial disease-free survival; tumor thickness of more than 3 mm and up to 9 mm had 44% subclinical nodal metastasis, 7% local recurrence, and 76% 5-year actuarial disease-free survival; tumor of more than 9 mm had 53% subclinical nodal metastasis, 24% local recurrence, and 66% 5-year actuarial disease-free survival. Conclusions. Tumor thickness should be considered in the management planning of patients with early oral tongue carcinoma. © 2002 Wiley Periodicals, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/172806
ISSN
2015 Impact Factor: 2.76
2015 SCImago Journal Rankings: 1.233
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYuen, APWen_US
dc.contributor.authorLam, KYen_US
dc.contributor.authorLam, LKen_US
dc.contributor.authorHo, CMen_US
dc.contributor.authorWong, Aen_US
dc.contributor.authorChow, TLen_US
dc.contributor.authorYuen, WFen_US
dc.contributor.authorWei, WIen_US
dc.date.accessioned2012-10-30T06:25:01Z-
dc.date.available2012-10-30T06:25:01Z-
dc.date.issued2002en_US
dc.identifier.citationHead And Neck, 2002, v. 24 n. 6, p. 513-520en_US
dc.identifier.issn1043-3074en_US
dc.identifier.urihttp://hdl.handle.net/10722/172806-
dc.description.abstractPurpose. This study aims at evaluation of the different prognostic models, including stage, tumor thickness, shape, malignancy grading of tumor invasive front, Martinez-Gimeno score, and pathologic features in the prediction of subclinical nodal metastasis, local recurrence, and survival of early T1 and T2 oral tongue squamous cell carcinoma. The results will have important implication for the management of patients. Patients and Methods. Seventy-two clinically T1 and T2 glossectomy specimens of oral tongue carcinoma were serially sectioned in 3-mm thickness for the evaluation of various pathologic features. The prognostic value in the prediction of subclinical nodal metastasis, local recurrence, and survival of different models were compared. Results. Among all the tumor parameters and predictive models being evaluated, tumor thickness was the only significant factor that had significant predictive value for subclinical nodal metastasis, local recurrence, and survival. With the use of 3-mm and 9-mm division, tumor of up to 3-mm thickness has 8% subclinical nodal metastasis, 0% local recurrence, and 100% 5-year actuarial disease-free survival; tumor thickness of more than 3 mm and up to 9 mm had 44% subclinical nodal metastasis, 7% local recurrence, and 76% 5-year actuarial disease-free survival; tumor of more than 9 mm had 53% subclinical nodal metastasis, 24% local recurrence, and 66% 5-year actuarial disease-free survival. Conclusions. Tumor thickness should be considered in the management planning of patients with early oral tongue carcinoma. © 2002 Wiley Periodicals, Inc.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137en_US
dc.relation.ispartofHead and Necken_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshCarcinoma, Squamous Cell - Mortality - Pathology - Surgeryen_US
dc.subject.meshDisease-Free Survivalen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLogistic Modelsen_US
dc.subject.meshLymphatic Metastasisen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasm Recurrence, Localen_US
dc.subject.meshNeoplasm Stagingen_US
dc.subject.meshPrognosisen_US
dc.subject.meshTongue Neoplasms - Mortality - Pathology - Surgeryen_US
dc.titlePrognostic factors of clinically stage I and II oral tongue carcinoma - A comparative study of stage, thickness, shape, growth pattern, invasive front malignancy grading, Martinez-Gimeno score, and pathologic featuresen_US
dc.typeArticleen_US
dc.identifier.emailWei, WI: hrmswwi@hku.hken_US
dc.identifier.authorityWei, WI=rp00323en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/hed.10094en_US
dc.identifier.pmid12112547-
dc.identifier.scopuseid_2-s2.0-0036264024en_US
dc.identifier.hkuros70222-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036264024&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume24en_US
dc.identifier.issue6en_US
dc.identifier.spage513en_US
dc.identifier.epage520en_US
dc.identifier.isiWOS:000176118400001-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridYuen, APW=7006290111en_US
dc.identifier.scopusauthoridLam, KY=7403657165en_US
dc.identifier.scopusauthoridLam, LK=7201984637en_US
dc.identifier.scopusauthoridHo, CM=7404652540en_US
dc.identifier.scopusauthoridWong, A=7403147614en_US
dc.identifier.scopusauthoridChow, TL=7203012370en_US
dc.identifier.scopusauthoridYuen, WF=7102761263en_US
dc.identifier.scopusauthoridWei, WI=7403321552en_US

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