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Article: Impact of total mesorectal excision on the results of surgery of distal rectal cancer

TitleImpact of total mesorectal excision on the results of surgery of distal rectal cancer
Authors
Issue Date2001
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.bjs.co.uk
Citation
British Journal Of Surgery, 2001, v. 88 n. 12, p. 1607-1612 How to Cite?
AbstractBackground: This study reviewed the results of surgery for distal rectal cancer (tumours within 6 cm of the anal verge) following the introduction of total mesorectal excision for rectal cancer in one institution. Methods: Two hundred and five patients who had undergone surgical resection of rectal cancer within 6 cm of the anal verge were included. The demographic, operative and follow-up data were collected prospectively. Comparisons were made between patients who had different surgical procedures. Results: Abdominoperineal resection APR was performed in 27.8 per cent of patients, falling from 36.0 per cent in the first 3 years to 20.0 per cent in the last 3 years of the study. The overall operative mortality rate was 1.5 per cent and the morbidity rate 30.2 per cent. With a mean follow-up of 36 months, local recurrence occurred in 28 of the 185 patients who had curative resection. The 5-year actuarial local recurrence rates for double-stapled anastomosis, peranal coloanal anastomosis and (APR) were 11.2, 34.6 and 23.5 per cent respectively. The local recurrence rate was significantly lower for double-stapled low anterior resection than for the other types of operation. The overall 5-year survival rate in patients with low anterior resection and APR was 69.1 and 51.1 per cent respectively (P = 0.12). Conclusion: With the practice of total mesorectal excision, APR was necessary in only 27.8 per cent of patients with rectal cancer within 6 cm of the anal verge. The local recurrence rate was much lower in patients with double-stapled low anterior resection than in those treated with APR or peranal anastomosis.
Persistent Identifierhttp://hdl.handle.net/10722/172791
ISSN
2015 Impact Factor: 5.596
2015 SCImago Journal Rankings: 2.966
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLaw, WLen_US
dc.contributor.authorChu, KWen_US
dc.date.accessioned2012-10-30T06:24:57Z-
dc.date.available2012-10-30T06:24:57Z-
dc.date.issued2001en_US
dc.identifier.citationBritish Journal Of Surgery, 2001, v. 88 n. 12, p. 1607-1612en_US
dc.identifier.issn0007-1323en_US
dc.identifier.urihttp://hdl.handle.net/10722/172791-
dc.description.abstractBackground: This study reviewed the results of surgery for distal rectal cancer (tumours within 6 cm of the anal verge) following the introduction of total mesorectal excision for rectal cancer in one institution. Methods: Two hundred and five patients who had undergone surgical resection of rectal cancer within 6 cm of the anal verge were included. The demographic, operative and follow-up data were collected prospectively. Comparisons were made between patients who had different surgical procedures. Results: Abdominoperineal resection APR was performed in 27.8 per cent of patients, falling from 36.0 per cent in the first 3 years to 20.0 per cent in the last 3 years of the study. The overall operative mortality rate was 1.5 per cent and the morbidity rate 30.2 per cent. With a mean follow-up of 36 months, local recurrence occurred in 28 of the 185 patients who had curative resection. The 5-year actuarial local recurrence rates for double-stapled anastomosis, peranal coloanal anastomosis and (APR) were 11.2, 34.6 and 23.5 per cent respectively. The local recurrence rate was significantly lower for double-stapled low anterior resection than for the other types of operation. The overall 5-year survival rate in patients with low anterior resection and APR was 69.1 and 51.1 per cent respectively (P = 0.12). Conclusion: With the practice of total mesorectal excision, APR was necessary in only 27.8 per cent of patients with rectal cancer within 6 cm of the anal verge. The local recurrence rate was much lower in patients with double-stapled low anterior resection than in those treated with APR or peranal anastomosis.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.bjs.co.uken_US
dc.relation.ispartofBritish Journal of Surgeryen_US
dc.rightsBritish Journal of Surgery. Copyright © John Wiley & Sons Ltd.-
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshColorectal Surgery - Adverse Effects - Methodsen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasm Recurrence, Local - Etiologyen_US
dc.subject.meshRectal Neoplasms - Surgeryen_US
dc.subject.meshSurgical Stapling - Methodsen_US
dc.subject.meshSurvival Analysisen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleImpact of total mesorectal excision on the results of surgery of distal rectal canceren_US
dc.typeArticleen_US
dc.identifier.emailLaw, WL: lawwl@hkucc.hku.hken_US
dc.identifier.authorityLaw, WL=rp00436en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1046/j.0007-1323.2001.01929.xen_US
dc.identifier.pmid11736973-
dc.identifier.scopuseid_2-s2.0-0035205495en_US
dc.identifier.hkuros71542-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0035205495&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume88en_US
dc.identifier.issue12en_US
dc.identifier.spage1607en_US
dc.identifier.epage1612en_US
dc.identifier.isiWOS:000172627400011-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridLaw, WL=7103147867en_US
dc.identifier.scopusauthoridChu, KW=7402453653en_US

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