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Conference Paper: In vivo autofluorescence of nasopharyngeal carcinoma and normal tissue

TitleIn vivo autofluorescence of nasopharyngeal carcinoma and normal tissue
Authors
KeywordsFluorescence
Spectroscopy
Imaging
Cancer
Issue Date2000
PublisherSPIE - International Society for Optical Engineering. The Journal's web site is located at http://spie.org/x1848.xml
Citation
The 3rd SIPE Conference on Optical Biopsy, San Jose, CA., 23-24 January 2000. In Proceedings of SPIE - The International Society For Optical Engineering, 2000, v. 3917, p. 9-15 How to Cite?
AbstractAn optical imaging and spectroscopy system has been developed for the study of in vivo fluorescence of nasopharngeal tissue through an endoscope. The system records the fluorescence signal in the imaging plane of the endoscopic system. This allows analyze the characteristics of the light induced fluorescence (LIF) spectra recorded by each pixel of the two dimensional detector which may be used for fluorescence endoscopic imaging. If the endoscope for fluorescence endoscopy is the same as one employed for the in vivo fluorescence study, the algorithms developed to distinguish the diseased tissue from normal tissue based on the in vivo fluorescence study should be highly reliable for fluorescence imaging of lesions. In this work, fluorescence spectra were collected from 27 full term patients. Different algorithms were tested for separation of cancerous lesions from normal tissue. High sensitivity and specificity were achieved.
DescriptionSIPE Conference on Optical Biopsy III, San Jose, CA, USA, 23-24 January 2000
Persistent Identifierhttp://hdl.handle.net/10722/172766
ISSN

 

DC FieldValueLanguage
dc.contributor.authorQu, Jianan Yen_US
dc.contributor.authorYuen, Po Wingen_US
dc.contributor.authorHuang, Zhijianen_US
dc.contributor.authorWei, William Ien_US
dc.date.accessioned2012-10-30T06:24:48Z-
dc.date.available2012-10-30T06:24:48Z-
dc.date.issued2000en_US
dc.identifier.citationThe 3rd SIPE Conference on Optical Biopsy, San Jose, CA., 23-24 January 2000. In Proceedings of SPIE - The International Society For Optical Engineering, 2000, v. 3917, p. 9-15en_US
dc.identifier.issn0277-786Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/172766-
dc.descriptionSIPE Conference on Optical Biopsy III, San Jose, CA, USA, 23-24 January 2000-
dc.description.abstractAn optical imaging and spectroscopy system has been developed for the study of in vivo fluorescence of nasopharngeal tissue through an endoscope. The system records the fluorescence signal in the imaging plane of the endoscopic system. This allows analyze the characteristics of the light induced fluorescence (LIF) spectra recorded by each pixel of the two dimensional detector which may be used for fluorescence endoscopic imaging. If the endoscope for fluorescence endoscopy is the same as one employed for the in vivo fluorescence study, the algorithms developed to distinguish the diseased tissue from normal tissue based on the in vivo fluorescence study should be highly reliable for fluorescence imaging of lesions. In this work, fluorescence spectra were collected from 27 full term patients. Different algorithms were tested for separation of cancerous lesions from normal tissue. High sensitivity and specificity were achieved.en_US
dc.languageengen_US
dc.publisherSPIE - International Society for Optical Engineering. The Journal's web site is located at http://spie.org/x1848.xmlen_US
dc.relation.ispartofProceedings of SPIE - The International Society for Optical Engineeringen_US
dc.rightsSPIE - the International Society for Optical Proceedings. Copyright © SPIE - International Society for Optical Engineering.-
dc.rightsCopyright 2000 Society of Photo-Optical Instrumentation Engineers.This paper was published in S P I E Conference on Optical biopsy III, San Jose, California, USA, 23-24 January 2000, v. 3917, p. 9-15 and is made available as an electronic reprint with permission of SPIE. One print or electronic copy may bemade for personal use only. Systematic or multiple reproduction, distribution to multiple locations viaelectronic or other means, duplication of any material in this paper for a fee or for commercial purposes,or modification of the content of the paper are prohibited.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectFluorescence-
dc.subjectSpectroscopy-
dc.subjectImaging-
dc.subjectCancer-
dc.titleIn vivo autofluorescence of nasopharyngeal carcinoma and normal tissueen_US
dc.typeConference_Paperen_US
dc.identifier.emailWei, William I: hrmswwi@hku.hken_US
dc.identifier.authorityWei, William I=rp00323en_US
dc.description.naturepublished_or_final_versionen_US
dc.identifier.doi10.1117/12.382732-
dc.identifier.scopuseid_2-s2.0-0033688548en_US
dc.identifier.hkuros58863-
dc.identifier.volume3917en_US
dc.identifier.spage9en_US
dc.identifier.epage15en_US
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridQu, Jianan Y=7201534954en_US
dc.identifier.scopusauthoridYuen, Po Wing=7103124007en_US
dc.identifier.scopusauthoridHuang, Zhijian=26662208200en_US
dc.identifier.scopusauthoridWei, William I=7403321552en_US
dc.customcontrol.immutablesml 160322 - amend-

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