File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Nasopharyngeal carcinoma: Early detection and prognostic factors

TitleNasopharyngeal carcinoma: Early detection and prognostic factors
Authors
Issue Date1993
PublisherElsevier (Singapore) Pte Ltd, Hong Kong Branch. The Journal's web site is located at http://www.elsevier.com/wps/find/journaldescription.cws_home/708511/description#description
Citation
Asian Journal Of Surgery, 1993, v. 16 n. 4, p. 262-266 How to Cite?
AbstractPopulation screening programmes which combine serology (antibodies against the Epstein Barr virus) and indirect mirror examination of the nasopharynx have successfully effected early detection of nasopharyngeal carcinoma (NPC) in studies in southern China. The cost of such a screening programme, and the lower prevalence of this disease in other parts of the world, however, may limit its wider application. Various features of NPC, including histopathology, titre of various antibodies against the EBV, sex and age at diagnosis have been reported as of prognostic importance but their value remains controversial, and stage remains the most important prognostic factor. Unfortunately, there has been no universally accepted stage classification for NPC. Most of the more widely accepted stage classifications do not take into consideration paranasopharyngeal extension of the tumour despite the computed tomography finding that such extension is an early event in the course of the disease. A quantitative method of evaluating paranasopharyngeal extension of the tumour has been proposed and found to have correlation with local control of the tumour. More controversy exists for the N staging over the relative importance of the size and the level of nodal involvement. Both of these have been documented as important prognostic parameters. They, perhaps, have changing importance at different times after treatment of the disease: size of node is more related to local control of the nodal disease and hence short term prognosis, while the level of nodal involvement is more related to distant metastases and, hence, long- term prognosis.
Persistent Identifierhttp://hdl.handle.net/10722/172697
ISSN
2015 Impact Factor: 0.912
2015 SCImago Journal Rankings: 0.427

 

DC FieldValueLanguage
dc.contributor.authorSham, JSTen_US
dc.contributor.authorYau, CCen_US
dc.contributor.authorWei, WIen_US
dc.contributor.authorChoy, Den_US
dc.date.accessioned2012-10-30T06:24:21Z-
dc.date.available2012-10-30T06:24:21Z-
dc.date.issued1993en_US
dc.identifier.citationAsian Journal Of Surgery, 1993, v. 16 n. 4, p. 262-266en_US
dc.identifier.issn1015-9584en_US
dc.identifier.urihttp://hdl.handle.net/10722/172697-
dc.description.abstractPopulation screening programmes which combine serology (antibodies against the Epstein Barr virus) and indirect mirror examination of the nasopharynx have successfully effected early detection of nasopharyngeal carcinoma (NPC) in studies in southern China. The cost of such a screening programme, and the lower prevalence of this disease in other parts of the world, however, may limit its wider application. Various features of NPC, including histopathology, titre of various antibodies against the EBV, sex and age at diagnosis have been reported as of prognostic importance but their value remains controversial, and stage remains the most important prognostic factor. Unfortunately, there has been no universally accepted stage classification for NPC. Most of the more widely accepted stage classifications do not take into consideration paranasopharyngeal extension of the tumour despite the computed tomography finding that such extension is an early event in the course of the disease. A quantitative method of evaluating paranasopharyngeal extension of the tumour has been proposed and found to have correlation with local control of the tumour. More controversy exists for the N staging over the relative importance of the size and the level of nodal involvement. Both of these have been documented as important prognostic parameters. They, perhaps, have changing importance at different times after treatment of the disease: size of node is more related to local control of the nodal disease and hence short term prognosis, while the level of nodal involvement is more related to distant metastases and, hence, long- term prognosis.en_US
dc.languageengen_US
dc.publisherElsevier (Singapore) Pte Ltd, Hong Kong Branch. The Journal's web site is located at http://www.elsevier.com/wps/find/journaldescription.cws_home/708511/description#descriptionen_US
dc.relation.ispartofAsian Journal of Surgeryen_US
dc.titleNasopharyngeal carcinoma: Early detection and prognostic factorsen_US
dc.typeArticleen_US
dc.identifier.emailWei, WI: hrmswwi@hku.hken_US
dc.identifier.authorityWei, WI=rp00323en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-0027881793en_US
dc.identifier.volume16en_US
dc.identifier.issue4en_US
dc.identifier.spage262en_US
dc.identifier.epage266en_US
dc.publisher.placeHong Kongen_US
dc.identifier.scopusauthoridSham, JST=7101655565en_US
dc.identifier.scopusauthoridYau, CC=7007038422en_US
dc.identifier.scopusauthoridWei, WI=7403321552en_US
dc.identifier.scopusauthoridChoy, D=7102939127en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats