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Article: Split-palate approach for gold grain implantation in nasopharyngeal carcinoma

TitleSplit-palate approach for gold grain implantation in nasopharyngeal carcinoma
Authors
Issue Date1990
PublisherAmerican Medical Association. The Journal's web site is located at http://www.archoto.com
Citation
Archives Of Otolaryngology - Head And Neck Surgery, 1990, v. 116 n. 5, p. 578-582 How to Cite?
AbstractAlthough nasopharyngeal carcinoma is radiosensitive, local failure after external radiotherapy is not uncommon and management of persistent or recurrent disease is a therapeutic challenge. The present review reports the use of brachy-therapy in the form of gold grain ( 198Au) implants in the treatment of 23 patients with recurrent or persistent primary nasopharyngeal carcinoma. The split-palate approach was employed in the insertion of the gold grains. This approach allows adequate exposure of the nasopharynx and accurate positioning of the implants. Implantation was successful in 21 patients, and local tumor control was achieved in 17 patients (81%) after a median follow-up of 23 months. Palatal fistula developed in 6 patients (26%); 5 healed with conservative management, and 1 had no functional disturbance. There was no operative mortality, and morbidity of the operation was minimal
Persistent Identifierhttp://hdl.handle.net/10722/172631
ISSN
2014 Impact Factor: 2.327
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWei, WIen_US
dc.contributor.authorSham, JSTen_US
dc.contributor.authorChoy, Den_US
dc.contributor.authorHo, CMen_US
dc.contributor.authorLam, KHen_US
dc.date.accessioned2012-10-30T06:23:54Z-
dc.date.available2012-10-30T06:23:54Z-
dc.date.issued1990en_US
dc.identifier.citationArchives Of Otolaryngology - Head And Neck Surgery, 1990, v. 116 n. 5, p. 578-582en_US
dc.identifier.issn0886-4470en_US
dc.identifier.urihttp://hdl.handle.net/10722/172631-
dc.description.abstractAlthough nasopharyngeal carcinoma is radiosensitive, local failure after external radiotherapy is not uncommon and management of persistent or recurrent disease is a therapeutic challenge. The present review reports the use of brachy-therapy in the form of gold grain ( 198Au) implants in the treatment of 23 patients with recurrent or persistent primary nasopharyngeal carcinoma. The split-palate approach was employed in the insertion of the gold grains. This approach allows adequate exposure of the nasopharynx and accurate positioning of the implants. Implantation was successful in 21 patients, and local tumor control was achieved in 17 patients (81%) after a median follow-up of 23 months. Palatal fistula developed in 6 patients (26%); 5 healed with conservative management, and 1 had no functional disturbance. There was no operative mortality, and morbidity of the operation was minimalen_US
dc.languageengen_US
dc.publisherAmerican Medical Association. The Journal's web site is located at http://www.archoto.comen_US
dc.relation.ispartofArchives of Otolaryngology - Head and Neck Surgeryen_US
dc.subject.meshBrachytherapy - Methodsen_US
dc.subject.meshCarcinoma - Radiotherapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGold Radioisotopes - Therapeutic Useen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNasopharyngeal Neoplasms - Radiotherapyen_US
dc.subject.meshNeoplasm Recurrence, Local - Radiotherapyen_US
dc.subject.meshPalate - Surgeryen_US
dc.subject.meshPalate, Soft - Surgeryen_US
dc.titleSplit-palate approach for gold grain implantation in nasopharyngeal carcinomaen_US
dc.typeArticleen_US
dc.identifier.emailWei, WI: hrmswwi@hku.hken_US
dc.identifier.authorityWei, WI=rp00323en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid2328116-
dc.identifier.scopuseid_2-s2.0-0025315480en_US
dc.identifier.volume116en_US
dc.identifier.issue5en_US
dc.identifier.spage578en_US
dc.identifier.epage582en_US
dc.identifier.isiWOS:A1990DC48000010-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridWei, WI=7403321552en_US
dc.identifier.scopusauthoridSham, JST=24472255400en_US
dc.identifier.scopusauthoridChoy, D=8663654500en_US
dc.identifier.scopusauthoridHo, CM=7404652540en_US
dc.identifier.scopusauthoridLam, KH=7403657342en_US

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