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Article: Regional chemotherapy through a saphenous vein graft for the treatment of head and neck cancers

TitleRegional chemotherapy through a saphenous vein graft for the treatment of head and neck cancers
Authors
Issue Date1987
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/28741
Citation
Cancer, 1987, v. 60 n. 7, p. 1432-1438 How to Cite?
AbstractRegional chemotherapy was given through a vein grafted between the common carotid and external carotid arteries to 20 patients who had a variety of advanced head and neck cancers. The objective response rate was 73.6%, which included 36.8% complete response. The medium duration of response was more than 10 months. The toxicity was mild and well tolerated. The complication rate associated with the procedure was low. This form of regional chemotherapy has significant advantages over the conventional form that uses durgs given through the retrograde temporal artery because the catheter-related complications are eliminated, the perfusion of the tumor can be maintained consistently, and, consequently, the response rate is high and the duration of response is increased.
Persistent Identifierhttp://hdl.handle.net/10722/172563
ISSN
2015 Impact Factor: 5.649
2015 SCImago Journal Rankings: 3.188
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChoi, TKen_US
dc.contributor.authorWei, Wen_US
dc.contributor.authorLau, WFen_US
dc.contributor.authorLam, KHen_US
dc.date.accessioned2012-10-30T06:23:25Z-
dc.date.available2012-10-30T06:23:25Z-
dc.date.issued1987en_US
dc.identifier.citationCancer, 1987, v. 60 n. 7, p. 1432-1438en_US
dc.identifier.issn0008-543Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/172563-
dc.description.abstractRegional chemotherapy was given through a vein grafted between the common carotid and external carotid arteries to 20 patients who had a variety of advanced head and neck cancers. The objective response rate was 73.6%, which included 36.8% complete response. The medium duration of response was more than 10 months. The toxicity was mild and well tolerated. The complication rate associated with the procedure was low. This form of regional chemotherapy has significant advantages over the conventional form that uses durgs given through the retrograde temporal artery because the catheter-related complications are eliminated, the perfusion of the tumor can be maintained consistently, and, consequently, the response rate is high and the duration of response is increased.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/28741en_US
dc.relation.ispartofCanceren_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshAntineoplastic Combined Chemotherapy Protocols - Administration & Dosage - Therapeutic Useen_US
dc.subject.meshChemotherapy, Cancer, Regional Perfusionen_US
dc.subject.meshCisplatin - Therapeutic Useen_US
dc.subject.meshDoxorubicin - Therapeutic Useen_US
dc.subject.meshFemaleen_US
dc.subject.meshFluorouracil - Therapeutic Useen_US
dc.subject.meshHead And Neck Neoplasms - Drug Therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSaphenous Veinen_US
dc.titleRegional chemotherapy through a saphenous vein graft for the treatment of head and neck cancersen_US
dc.typeArticleen_US
dc.identifier.emailWei, W: hrmswwi@hku.hken_US
dc.identifier.authorityWei, W=rp00323en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/1097-0142(19871001)60:7<1432::AID-CNCR2820600704>3.0.CO;2-2-
dc.identifier.pmid3621124-
dc.identifier.scopuseid_2-s2.0-0023280666en_US
dc.identifier.volume60en_US
dc.identifier.issue7en_US
dc.identifier.spage1432en_US
dc.identifier.epage1438en_US
dc.identifier.isiWOS:A1987K249600003-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridChoi, TK=7202770029en_US
dc.identifier.scopusauthoridWei, W=7403321552en_US
dc.identifier.scopusauthoridLau, WF=7402933215en_US
dc.identifier.scopusauthoridLam, KH=7403657342en_US

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