File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Spatiotemporal dipole source localization of face processing ERPs in adolescents: A preliminary study

TitleSpatiotemporal dipole source localization of face processing ERPs in adolescents: A preliminary study
Authors
Issue Date2009
PublisherBioMed Central Ltd. The Journal's web site is located at http://www.behavioralandbrainfunctions.com/home
Citation
Behavioral And Brain Functions, 2009, v. 5 How to Cite?
AbstractBackground: Despite extensive investigation of the neural systems for face perception and emotion recognition in adults and young children in the past, the precise temporal activation of brain sources specific to the processing of emotional facial expressions in older children and adolescents is not well known. This preliminary study aims to trace the spatiotemporal dynamics of facial emotion processing during adolescence and provide a basis for future developmental studies and comparisons with patient populations that have social-emotional deficits such as autism. Methods: We presented pictures showing happy, angry, fearful, or neutral facial expressions to healthy adolescents (aged 10-16 years) and recorded 128-channel event-related potentials (ERPs) while they performed an emotion discrimination task. ERP components were analyzed for effects of age and emotion on amplitude and latency. The underlying cortical sources of scalp ERP activity were modeled as multiple equivalent current dipoles using Brain Electrical Source Analysis (BESA). Results: Initial global/holistic processing of faces (P1) tookplace in the visual association cortex (lingual gyrus) around 120 ms post-stimulus. Next, structural encoding of facial features (N170) occurred between 160-200 ms in the inferior temporal/fusiform region, and perhaps early emotion processing (Vertex Positive Potential or VPP) in the amygdala and orbitofrontal cortex. Finally, cognitive analysis of facial expressions (P2) in the prefrontal cortex and emotional reactions in somatosensory areas were observed from about 230 ms onwards. The temporal sequence of cortical source activation in response to facial emotion processing was occipital, prefrontal, fusiform, parietal for young adolescents and occipital, limbic, inferior temporal, and prefrontal for older adolescents. Conclusion: This is a first report of high-density ERP dipole source analysis in healthy adolescents which traces the sequence of neural activity within the first 500 ms of categorizing emotion from faces. Our spatio-temporal brain source models showed the presence of adult-like cortical networks for face processing in adolescents, whose functional specificity to different emotions appear to be not yet fully mature. Age-related differences in brain activation patterns illustrate the continued development and maturation of distinct neural systems for processing facial expressions during adolescence and possible changes in emotion perception, experience, and reaction with age. © 2009 Wong et al; licensee BioMed Central Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/171955
ISSN
2015 Impact Factor: 1.72
2015 SCImago Journal Rankings: 0.989
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, TKWen_HK
dc.contributor.authorFung, PCWen_HK
dc.contributor.authorMcAlonan, GMen_HK
dc.contributor.authorChua, SEen_HK
dc.date.accessioned2012-10-30T06:18:47Z-
dc.date.available2012-10-30T06:18:47Z-
dc.date.issued2009en_HK
dc.identifier.citationBehavioral And Brain Functions, 2009, v. 5en_HK
dc.identifier.issn1744-9081en_HK
dc.identifier.urihttp://hdl.handle.net/10722/171955-
dc.description.abstractBackground: Despite extensive investigation of the neural systems for face perception and emotion recognition in adults and young children in the past, the precise temporal activation of brain sources specific to the processing of emotional facial expressions in older children and adolescents is not well known. This preliminary study aims to trace the spatiotemporal dynamics of facial emotion processing during adolescence and provide a basis for future developmental studies and comparisons with patient populations that have social-emotional deficits such as autism. Methods: We presented pictures showing happy, angry, fearful, or neutral facial expressions to healthy adolescents (aged 10-16 years) and recorded 128-channel event-related potentials (ERPs) while they performed an emotion discrimination task. ERP components were analyzed for effects of age and emotion on amplitude and latency. The underlying cortical sources of scalp ERP activity were modeled as multiple equivalent current dipoles using Brain Electrical Source Analysis (BESA). Results: Initial global/holistic processing of faces (P1) tookplace in the visual association cortex (lingual gyrus) around 120 ms post-stimulus. Next, structural encoding of facial features (N170) occurred between 160-200 ms in the inferior temporal/fusiform region, and perhaps early emotion processing (Vertex Positive Potential or VPP) in the amygdala and orbitofrontal cortex. Finally, cognitive analysis of facial expressions (P2) in the prefrontal cortex and emotional reactions in somatosensory areas were observed from about 230 ms onwards. The temporal sequence of cortical source activation in response to facial emotion processing was occipital, prefrontal, fusiform, parietal for young adolescents and occipital, limbic, inferior temporal, and prefrontal for older adolescents. Conclusion: This is a first report of high-density ERP dipole source analysis in healthy adolescents which traces the sequence of neural activity within the first 500 ms of categorizing emotion from faces. Our spatio-temporal brain source models showed the presence of adult-like cortical networks for face processing in adolescents, whose functional specificity to different emotions appear to be not yet fully mature. Age-related differences in brain activation patterns illustrate the continued development and maturation of distinct neural systems for processing facial expressions during adolescence and possible changes in emotion perception, experience, and reaction with age. © 2009 Wong et al; licensee BioMed Central Ltd.en_HK
dc.languageengen_US
dc.publisherBioMed Central Ltd. The Journal's web site is located at http://www.behavioralandbrainfunctions.com/homeen_HK
dc.relation.ispartofBehavioral and Brain Functionsen_HK
dc.titleSpatiotemporal dipole source localization of face processing ERPs in adolescents: A preliminary studyen_HK
dc.typeArticleen_HK
dc.identifier.emailMcAlonan, GM: mcalonan@hkucc.hku.hken_HK
dc.identifier.emailChua, SE: sechua@hku.hken_HK
dc.identifier.authorityMcAlonan, GM=rp00475en_HK
dc.identifier.authorityChua, SE=rp00438en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1186/1744-9081-5-16en_HK
dc.identifier.pmid19284600-
dc.identifier.scopuseid_2-s2.0-63749128594en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-63749128594&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume5en_HK
dc.identifier.isiWOS:000264763300001-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWong, TKW=7403531187en_HK
dc.identifier.scopusauthoridFung, PCW=7101613315en_HK
dc.identifier.scopusauthoridMcAlonan, GM=6603123011en_HK
dc.identifier.scopusauthoridChua, SE=7201550427en_HK
dc.identifier.citeulike4171139-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats