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Article: Progressive deterioration of soft neurological signs in chronic schizophrenic patients

TitleProgressive deterioration of soft neurological signs in chronic schizophrenic patients
Authors
Issue Date2000
PublisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ACP
Citation
Acta Psychiatrica Scandinavica, 2000, v. 102 n. 5, p. 342-349 How to Cite?
AbstractObjective: Neurological signs are found to be increased in schizophrenia in cross-sectional studies. Whether they progress with time is an important issue in addressing the course of the illness. Method: The current study investigated different groups of neurological signs in 43 stable chronic schizophrenic patients over a 3-year period using an operationalized instrument. Results: While symptoms and medication have remained largely unchanged in the 3-year period, significant increase in soft neurological signs (SNS) ('motor coordination', 'sensory integration' and 'disinhibition') has been observed. This contrasted with the stability of 'pyramidal', 'extrapyramidal', 'dyskinesia' and 'catatonia' signs. The increase in SNS appears not to be related to age, illness duration, symptoms or medication. Conclusion: This finding suggests that SNS represent a marker sensitive to a possible late deterioration process in the course of a schizophrenic illness. (C) Munksgaard 2000.
Persistent Identifierhttp://hdl.handle.net/10722/171896
ISSN
2015 Impact Factor: 6.128
2015 SCImago Journal Rankings: 2.518
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChen, EYHen_US
dc.contributor.authorKwok, CLen_US
dc.contributor.authorAu, JWYen_US
dc.contributor.authorChen, RYLen_US
dc.contributor.authorLau, BSTen_US
dc.date.accessioned2012-10-30T06:18:17Z-
dc.date.available2012-10-30T06:18:17Z-
dc.date.issued2000en_US
dc.identifier.citationActa Psychiatrica Scandinavica, 2000, v. 102 n. 5, p. 342-349en_US
dc.identifier.issn0001-690Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/171896-
dc.description.abstractObjective: Neurological signs are found to be increased in schizophrenia in cross-sectional studies. Whether they progress with time is an important issue in addressing the course of the illness. Method: The current study investigated different groups of neurological signs in 43 stable chronic schizophrenic patients over a 3-year period using an operationalized instrument. Results: While symptoms and medication have remained largely unchanged in the 3-year period, significant increase in soft neurological signs (SNS) ('motor coordination', 'sensory integration' and 'disinhibition') has been observed. This contrasted with the stability of 'pyramidal', 'extrapyramidal', 'dyskinesia' and 'catatonia' signs. The increase in SNS appears not to be related to age, illness duration, symptoms or medication. Conclusion: This finding suggests that SNS represent a marker sensitive to a possible late deterioration process in the course of a schizophrenic illness. (C) Munksgaard 2000.en_US
dc.languageengen_US
dc.publisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ACPen_US
dc.relation.ispartofActa Psychiatrica Scandinavicaen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshChronic Diseaseen_US
dc.subject.meshDisease Progressionen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMotor Skills Disorders - Etiologyen_US
dc.subject.meshMultivariate Analysisen_US
dc.subject.meshNeurologic Examinationen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshReflex, Abnormalen_US
dc.subject.meshSchizophrenia - Complications - Diagnosis - Physiopathologyen_US
dc.subject.meshTime Factorsen_US
dc.titleProgressive deterioration of soft neurological signs in chronic schizophrenic patientsen_US
dc.typeArticleen_US
dc.identifier.emailChen, EYH:eyhchen@hku.hken_US
dc.identifier.authorityChen, EYH=rp00392en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1034/j.1600-0447.2000.102005342.xen_US
dc.identifier.pmid11098805-
dc.identifier.scopuseid_2-s2.0-0033765650en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033765650&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume102en_US
dc.identifier.issue5en_US
dc.identifier.spage342en_US
dc.identifier.epage349en_US
dc.identifier.isiWOS:000165160000005-
dc.publisher.placeDenmarken_US
dc.identifier.scopusauthoridChen, EYH=7402315729en_US
dc.identifier.scopusauthoridKwok, CL=35989055900en_US
dc.identifier.scopusauthoridAu, JWY=7101921208en_US
dc.identifier.scopusauthoridChen, RYL=16635066600en_US
dc.identifier.scopusauthoridLau, BST=7102223655en_US
dc.identifier.citeulike10114182-

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