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Article: The neurodevelopmental theory of schizophrenia: Evidence concerning structure and neurospychology | De ontwikkelingsneurologische theorie van schizofrenie: Bewijsmateriaal betreffende structuur en neuropsychologie

TitleThe neurodevelopmental theory of schizophrenia: Evidence concerning structure and neurospychology | De ontwikkelingsneurologische theorie van schizofrenie: Bewijsmateriaal betreffende structuur en neuropsychologie
Authors
KeywordsFunctional
Imaging
Neurodevelopmental
Neuropsychology
Schizophrenia
Structure
Issue Date1996
PublisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ACN
Citation
Acta Neuropsychiatrica, 1996, v. 8 n. 2, p. 25-34 How to Cite?
AbstractSevere schizophrenics as a group show subtle abnormalities of cerebral structure. Cerebral ventricular enlargement is the best replicated finding, and this tends to be associated with impairment of neuropsychological performance. The idea that these abnormalities have a neurodevelopmental origin gains indirect support from the, admittedly less consistent, evidence of abnormalities of cerebral asymmetry and of neuronal migration in adult schizophrenics, as well as from the behavioural, psychomotor, and cognitive impairments reported in pre-schizophrenic children. However, the relationship between childhood and adult neuropsychological and brain structural findings has not been proven, and we do not know whether only some schizophrenics have a developmental origin, or whether patients differ only in the degree of developmental impairment that they show.
Persistent Identifierhttp://hdl.handle.net/10722/171887
ISSN
2012 Impact Factor: 0.606
2015 SCImago Journal Rankings: 0.421
References

 

DC FieldValueLanguage
dc.contributor.authorChua, SEen_US
dc.contributor.authorMurray, RMen_US
dc.date.accessioned2012-10-30T06:18:12Z-
dc.date.available2012-10-30T06:18:12Z-
dc.date.issued1996en_US
dc.identifier.citationActa Neuropsychiatrica, 1996, v. 8 n. 2, p. 25-34en_US
dc.identifier.issn0924-2708en_US
dc.identifier.urihttp://hdl.handle.net/10722/171887-
dc.description.abstractSevere schizophrenics as a group show subtle abnormalities of cerebral structure. Cerebral ventricular enlargement is the best replicated finding, and this tends to be associated with impairment of neuropsychological performance. The idea that these abnormalities have a neurodevelopmental origin gains indirect support from the, admittedly less consistent, evidence of abnormalities of cerebral asymmetry and of neuronal migration in adult schizophrenics, as well as from the behavioural, psychomotor, and cognitive impairments reported in pre-schizophrenic children. However, the relationship between childhood and adult neuropsychological and brain structural findings has not been proven, and we do not know whether only some schizophrenics have a developmental origin, or whether patients differ only in the degree of developmental impairment that they show.en_US
dc.languageengen_US
dc.publisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ACNen_US
dc.relation.ispartofActa Neuropsychiatricaen_US
dc.subjectFunctionalen_US
dc.subjectImagingen_US
dc.subjectNeurodevelopmentalen_US
dc.subjectNeuropsychologyen_US
dc.subjectSchizophreniaen_US
dc.subjectStructureen_US
dc.titleThe neurodevelopmental theory of schizophrenia: Evidence concerning structure and neurospychology | De ontwikkelingsneurologische theorie van schizofrenie: Bewijsmateriaal betreffende structuur en neuropsychologieen_US
dc.typeArticleen_US
dc.identifier.emailChua, SE:sechua@hku.hken_US
dc.identifier.authorityChua, SE=rp00438en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-0029906454en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0029906454&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume8en_US
dc.identifier.issue2en_US
dc.identifier.spage25en_US
dc.identifier.epage34en_US
dc.publisher.placeDenmarken_US
dc.identifier.scopusauthoridChua, SE=7201550427en_US
dc.identifier.scopusauthoridMurray, RM=35406239400en_US

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