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Article: Calcium Signaling by Cyclic ADP-Ribose and NAADP: A Decade of Exploration

TitleCalcium Signaling by Cyclic ADP-Ribose and NAADP: A Decade of Exploration
Authors
Issue Date1998
Citation
Cell Biochemistry And Biophysics, 1998, v. 28 n. 1, p. 1-17 How to Cite?
AbstractCa2+ mobilization as a signaling mechanism has been placed on center stage with the discovery of the first Ca2+ messenger, inositol trisphosphate (IP3). This article focuses on two new Ca2+ release activators, which mobilize internal Ca2+ stores via mechanisms totally independent of IP3. They are cyclic ADP-ribose (cADPR) and nicotinic acid dinucleotide phosphate (NAADP), metabolites derived respectively from NAD and NADP. Major advances in the past decade in the understanding of these two novel signaling mechanisms are chronologically summarized.
Persistent Identifierhttp://hdl.handle.net/10722/171648
ISSN
2015 Impact Factor: 1.627
2015 SCImago Journal Rankings: 0.598
References

 

DC FieldValueLanguage
dc.contributor.authorLee, HCen_US
dc.date.accessioned2012-10-30T06:16:08Z-
dc.date.available2012-10-30T06:16:08Z-
dc.date.issued1998en_US
dc.identifier.citationCell Biochemistry And Biophysics, 1998, v. 28 n. 1, p. 1-17en_US
dc.identifier.issn1085-9195en_US
dc.identifier.urihttp://hdl.handle.net/10722/171648-
dc.description.abstractCa2+ mobilization as a signaling mechanism has been placed on center stage with the discovery of the first Ca2+ messenger, inositol trisphosphate (IP3). This article focuses on two new Ca2+ release activators, which mobilize internal Ca2+ stores via mechanisms totally independent of IP3. They are cyclic ADP-ribose (cADPR) and nicotinic acid dinucleotide phosphate (NAADP), metabolites derived respectively from NAD and NADP. Major advances in the past decade in the understanding of these two novel signaling mechanisms are chronologically summarized.en_US
dc.languageengen_US
dc.relation.ispartofCell Biochemistry and Biophysicsen_US
dc.subject.meshAdenosine Diphosphate Ribose - Analogs & Derivatives - Chemistry - Physiologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCalcium - Physiologyen_US
dc.subject.meshCyclic Adp-Riboseen_US
dc.subject.meshHumansen_US
dc.subject.meshModels, Molecularen_US
dc.subject.meshNad - Analogs & Derivatives - Chemistry - Physiologyen_US
dc.subject.meshSignal Transductionen_US
dc.titleCalcium Signaling by Cyclic ADP-Ribose and NAADP: A Decade of Explorationen_US
dc.typeArticleen_US
dc.identifier.emailLee, HC:leehc@hku.hken_US
dc.identifier.authorityLee, HC=rp00545en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid9386889-
dc.identifier.scopuseid_2-s2.0-0031972642en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031972642&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume28en_US
dc.identifier.issue1en_US
dc.identifier.spage1en_US
dc.identifier.epage17en_US
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLee, HC=26642959100en_US

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