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Article: Modulation of postjunctional α-adrenergic responsiveness by local changes in temperature

TitleModulation of postjunctional α-adrenergic responsiveness by local changes in temperature
Authors
Issue Date1985
PublisherPortland Press Ltd. The Journal's web site is located at http://www.clinsci.org/
Citation
Clinical Science, 1985, v. 68 SUPPL. 10, p. 121S-123S How to Cite?
Abstract1. In canine cutaneous veins, local moderate warming (37°-41°C) augments the responsiveness to postjunctional α1-adrenergic stimulation but depresses that to postjunctional α2-adrenergic activation. Moderate cooling (37° C-24°C) has the opposite effect. 2. The effects of warming and cooling on α1-adrenergic responses are buffered by a large receptor reserve, allowing for the predominance of alterations in α2-adrenergic responsiveness.
Persistent Identifierhttp://hdl.handle.net/10722/170772
ISSN
2015 Impact Factor: 4.996
2015 SCImago Journal Rankings: 2.427
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorVanhoutte, PMen_US
dc.contributor.authorCooke, JPen_US
dc.contributor.authorLindblad, LEen_US
dc.date.accessioned2012-10-30T06:10:47Z-
dc.date.available2012-10-30T06:10:47Z-
dc.date.issued1985en_US
dc.identifier.citationClinical Science, 1985, v. 68 SUPPL. 10, p. 121S-123Sen_US
dc.identifier.issn0143-5221en_US
dc.identifier.urihttp://hdl.handle.net/10722/170772-
dc.description.abstract1. In canine cutaneous veins, local moderate warming (37°-41°C) augments the responsiveness to postjunctional α1-adrenergic stimulation but depresses that to postjunctional α2-adrenergic activation. Moderate cooling (37° C-24°C) has the opposite effect. 2. The effects of warming and cooling on α1-adrenergic responses are buffered by a large receptor reserve, allowing for the predominance of alterations in α2-adrenergic responsiveness.en_US
dc.languageengen_US
dc.publisherPortland Press Ltd. The Journal's web site is located at http://www.clinsci.org/en_US
dc.relation.ispartofClinical Scienceen_US
dc.subject.meshAdrenergic Alpha-Agonists - Pharmacologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshDogsen_US
dc.subject.meshMuscle Contraction - Drug Effectsen_US
dc.subject.meshNeuromuscular Junction - Drug Effectsen_US
dc.subject.meshNorepinephrine - Pharmacologyen_US
dc.subject.meshPotassium - Pharmacologyen_US
dc.subject.meshReceptors, Adrenergic, Alpha - Drug Effects - Physiologyen_US
dc.subject.meshSaphenous Veinen_US
dc.subject.meshSynaptic Transmission - Drug Effectsen_US
dc.subject.meshTemperatureen_US
dc.titleModulation of postjunctional α-adrenergic responsiveness by local changes in temperatureen_US
dc.typeArticleen_US
dc.identifier.emailVanhoutte, PM:vanhoutt@hku.hken_US
dc.identifier.authorityVanhoutte, PM=rp00238en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid2857606-
dc.identifier.scopuseid_2-s2.0-0021911566en_US
dc.identifier.volume68en_US
dc.identifier.issueSUPPL. 10en_US
dc.identifier.spage121Sen_US
dc.identifier.epage123Sen_US
dc.identifier.isiWOS:A1985ACE9200024-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridVanhoutte, PM=7202304247en_US
dc.identifier.scopusauthoridCooke, JP=7202378672en_US
dc.identifier.scopusauthoridLindblad, LE=19735934700en_US

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