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Article: Serotonin and arterial vessels

TitleSerotonin and arterial vessels
Authors
Vanhoutte, PMCohen, RAVan Nueten, JM
KeywordsAdrenergic neurotransmission
Endothelium-dependent relaxation
Serotonergic receptors
Serotonergic transmission
Vascular smooth muscle
Issue Date1984
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.cardiovascularpharm.com/
Citation
Journal Of Cardiovascular Pharmacology, 1984, v. 6 SUPPL. 2, p. S421-S428 How to Cite?
DOI: http://dx.doi.org/10.1097/00005344-198406002-00017
AbstractThe vasoconstrictor effects of serotonin can be explained by (a) activation of serotonergic receptors on vascular smooth muscle, (b) activation, directly or indirectly, of postjunctional α-adrenoceptors, and (c) amplification of the response to other vasoactive agonists. Vasoconstrictor responses to serotonin may play a role in the etiology of vasospasm and in the maintenance of the augmented peripheral resistance in arterial hypertension. The vasodilator effects of serotonin can be caused by (a) inhibiting vascular smooth muscle directly, (b) releasing other inhibitory substances, such as vasoactive intestinal polypeptide, (c) inhibiting adrenergic neurotransmission, and (d) triggering of endothelium-dependent relaxations.
Persistent Identifierhttp://hdl.handle.net/10722/170728
ISSN
0160-2446
2021 Impact Factor: 3.271
2020 SCImago Journal Rankings: 0.762
ISI Accession Number ID
WOS:A1984SX70200017

 

DC FieldValueLanguage
dc.contributor.authorVanhoutte, PMen_US
dc.contributor.authorCohen, RAen_US
dc.contributor.authorVan Nueten, JMen_US
dc.date.accessioned2012-10-30T06:10:37Z-
dc.date.available2012-10-30T06:10:37Z-
dc.date.issued1984en_US
dc.identifier.citationJournal Of Cardiovascular Pharmacology, 1984, v. 6 SUPPL. 2, p. S421-S428en_US
dc.identifier.issn0160-2446en_US
dc.identifier.urihttp://hdl.handle.net/10722/170728-
dc.description.abstractThe vasoconstrictor effects of serotonin can be explained by (a) activation of serotonergic receptors on vascular smooth muscle, (b) activation, directly or indirectly, of postjunctional α-adrenoceptors, and (c) amplification of the response to other vasoactive agonists. Vasoconstrictor responses to serotonin may play a role in the etiology of vasospasm and in the maintenance of the augmented peripheral resistance in arterial hypertension. The vasodilator effects of serotonin can be caused by (a) inhibiting vascular smooth muscle directly, (b) releasing other inhibitory substances, such as vasoactive intestinal polypeptide, (c) inhibiting adrenergic neurotransmission, and (d) triggering of endothelium-dependent relaxations.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.cardiovascularpharm.com/en_US
dc.relation.ispartofJournal of Cardiovascular Pharmacologyen_US
dc.subjectAdrenergic neurotransmission-
dc.subjectEndothelium-dependent relaxation-
dc.subjectSerotonergic receptors-
dc.subjectSerotonergic transmission-
dc.subjectVascular smooth muscle-
dc.subject.meshAnimalsen_US
dc.subject.meshArteries - Physiologyen_US
dc.subject.meshCoronary Vessels - Physiologyen_US
dc.subject.meshEndothelium - Cytologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMuscle Contraction - Drug Effectsen_US
dc.subject.meshMuscle, Smooth, Vascular - Drug Effectsen_US
dc.subject.meshPlatelet Aggregation - Drug Effectsen_US
dc.subject.meshSerotonin - Pharmacology - Physiologyen_US
dc.subject.meshVasoconstriction - Drug Effectsen_US
dc.subject.meshVasodilation - Drug Effectsen_US
dc.titleSerotonin and arterial vesselsen_US
dc.typeArticleen_US
dc.identifier.emailVanhoutte, PM:vanhoutt@hku.hken_US
dc.identifier.authorityVanhoutte, PM=rp00238en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/00005344-198406002-00017-
dc.identifier.pmid6206351-
dc.identifier.scopuseid_2-s2.0-0021173895en_US
dc.identifier.volume6en_US
dc.identifier.issueSUPPL. 2en_US
dc.identifier.spageS421en_US
dc.identifier.epageS428en_US
dc.identifier.isiWOS:A1984SX70200017-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridVanhoutte, PM=7202304247en_US
dc.identifier.scopusauthoridCohen, RA=35562815800en_US
dc.identifier.scopusauthoridVan Nueten, JM=7005700327en_US
dc.identifier.issnl0160-2446-

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