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Article: Enhanced release of noradrenaline in the kidney of the young spontaneously hypertensive rat

TitleEnhanced release of noradrenaline in the kidney of the young spontaneously hypertensive rat
Authors
Collis, MGDe Mey, CVanhoutte, PM
Issue Date1979
PublisherPortland Press Ltd. The Journal's web site is located at http://www.clinsci.org/
Citation
Clinical Science, 1979, v. 57 SUPPL. 5, p. 233-234 How to Cite?
DOI: http://dx.doi.org/10.1042/cs057233s
AbstractVascular reactivity and noradrenaline overflow were studied in Tyrode solution-perfused kidneys from young (6 weeks) normotensive and spontaneously hypertensive (SH) rats. The vasoconstrictor response to nerve stimulation was greater in the kidneys from young SH rats than in those from young control rats. Nerve stimulation evoked a greater release of noradrenaline in the kidneys from young SH rats than in those from normotensive animals. The results demonstrate that the renal sympathetic nerves release more noradrenaline than normal in the young SH rats, which could be an important factor in causing hypertension.
Persistent Identifierhttp://hdl.handle.net/10722/170592
ISSN
0143-5221
2021 Impact Factor: 6.876
2020 SCImago Journal Rankings: 1.910
ISI Accession Number ID
WOS:A1979JG73600059

 

DC FieldValueLanguage
dc.contributor.authorCollis, MGen_US
dc.contributor.authorDe Mey, Cen_US
dc.contributor.authorVanhoutte, PMen_US
dc.date.accessioned2012-10-30T06:10:04Z-
dc.date.available2012-10-30T06:10:04Z-
dc.date.issued1979en_US
dc.identifier.citationClinical Science, 1979, v. 57 SUPPL. 5, p. 233-234en_US
dc.identifier.issn0143-5221en_US
dc.identifier.urihttp://hdl.handle.net/10722/170592-
dc.description.abstractVascular reactivity and noradrenaline overflow were studied in Tyrode solution-perfused kidneys from young (6 weeks) normotensive and spontaneously hypertensive (SH) rats. The vasoconstrictor response to nerve stimulation was greater in the kidneys from young SH rats than in those from young control rats. Nerve stimulation evoked a greater release of noradrenaline in the kidneys from young SH rats than in those from normotensive animals. The results demonstrate that the renal sympathetic nerves release more noradrenaline than normal in the young SH rats, which could be an important factor in causing hypertension.en_US
dc.languageengen_US
dc.publisherPortland Press Ltd. The Journal's web site is located at http://www.clinsci.org/en_US
dc.relation.ispartofClinical Scienceen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBlood Pressureen_US
dc.subject.meshHypertension - Metabolism - Physiopathologyen_US
dc.subject.meshKidney - Innervation - Metabolismen_US
dc.subject.meshNorepinephrine - Metabolismen_US
dc.subject.meshRatsen_US
dc.subject.meshSympathetic Nervous System - Physiology - Physiopathologyen_US
dc.titleEnhanced release of noradrenaline in the kidney of the young spontaneously hypertensive raten_US
dc.typeArticleen_US
dc.identifier.emailVanhoutte, PM:vanhoutt@hku.hken_US
dc.identifier.authorityVanhoutte, PM=rp00238en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1042/cs057233s-
dc.identifier.pmid540438-
dc.identifier.scopuseid_2-s2.0-0018636650en_US
dc.identifier.volume57en_US
dc.identifier.issueSUPPL. 5en_US
dc.identifier.spage233en_US
dc.identifier.epage234en_US
dc.identifier.isiWOS:A1979JG73600059-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridCollis, MG=7005797278en_US
dc.identifier.scopusauthoridDe Mey, C=7006663615en_US
dc.identifier.scopusauthoridVanhoutte, PM=7202304247en_US
dc.identifier.issnl0143-5221-

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