File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Functional implications of the right ventricular myocardial performance index in patients after surgical repair of tetralogy of Fallot

TitleFunctional implications of the right ventricular myocardial performance index in patients after surgical repair of tetralogy of Fallot
Authors
Issue Date2008
PublisherSpringer Japan. The Journal's web site is located at www.springerlink.com/openurl.asp?genre=journal&issn=0910-8327
Citation
Heart And Vessels, 2008, v. 23 n. 2, p. 112-117 How to Cite?
AbstractThe myocardial performance index (MPI) has been proposed to be a simple echocardiographic index of right ventricular (RV) function in patients after surgical repair of tetralogy of Fallot (TOF). However, its functional status remains to be clarified. The functional implications of RV MPI were determined by exploring its relationships with parameters of RV function as derived from cardiovascular magnetic resonance (CMR), and exercise capacity of postoperative TOF patients Thirty patients (11 males), aged 15.6 3.1 years, who have undergone surgical repair of TOF at 4.0 1.8 years, were studied. The RV and left ventricular (LV) MPIs determined using pulsed-wave Doppler echocardiography were related to CMR-derived RV and LV ejection fractions, and pulmonary regurgitant fraction and treadmill exercise testing parameters. Log RV MPI correlated positively with log LV MPI (r = 0.38, P = 0.037) and negatively with CMR-derived RV ejection fraction (r = -0.4, P = 0.028) and pulmonary regurgitant fraction (r = -0.4, P = 0.031). No significant correlations were found between LV MPI and any of the CMR parameters. Using receiver operated characteristics analysis, a cutoff value of 0.30 for RV MPI was found to have a sensitivity of 100% and specificity of 74% in predicting a RV ejection fraction <35%. Right ventricular, but not LV, MPI correlated inversely with exercise duration (r = -0.45, P = 0.013) and peak oxygen consumption (VO 2 max) (r = -0.56, P = 0.001). Multivariate analysis identified RV MPI (= -0.6, P < 0.001), male sex (= 0.44, P = 0.01), and duration from surgery (= -0.30, P = 0.019) as significant determinants of VO 2 max. Increased MPI is a reflection of reduced RV ejection fraction and exercise capacity in patients after TOF repair. © Springer Japan 2008.
Persistent Identifierhttp://hdl.handle.net/10722/170395
ISSN
2014 Impact Factor: 2.065
2014 SCImago Journal Rankings: 0.649
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, EWYen_US
dc.contributor.authorLam, WWMen_US
dc.contributor.authorCheung, SCWen_US
dc.contributor.authorCheung, YFen_US
dc.date.accessioned2012-10-30T06:08:00Z-
dc.date.available2012-10-30T06:08:00Z-
dc.date.issued2008en_US
dc.identifier.citationHeart And Vessels, 2008, v. 23 n. 2, p. 112-117en_US
dc.identifier.issn0910-8327en_US
dc.identifier.urihttp://hdl.handle.net/10722/170395-
dc.description.abstractThe myocardial performance index (MPI) has been proposed to be a simple echocardiographic index of right ventricular (RV) function in patients after surgical repair of tetralogy of Fallot (TOF). However, its functional status remains to be clarified. The functional implications of RV MPI were determined by exploring its relationships with parameters of RV function as derived from cardiovascular magnetic resonance (CMR), and exercise capacity of postoperative TOF patients Thirty patients (11 males), aged 15.6 3.1 years, who have undergone surgical repair of TOF at 4.0 1.8 years, were studied. The RV and left ventricular (LV) MPIs determined using pulsed-wave Doppler echocardiography were related to CMR-derived RV and LV ejection fractions, and pulmonary regurgitant fraction and treadmill exercise testing parameters. Log RV MPI correlated positively with log LV MPI (r = 0.38, P = 0.037) and negatively with CMR-derived RV ejection fraction (r = -0.4, P = 0.028) and pulmonary regurgitant fraction (r = -0.4, P = 0.031). No significant correlations were found between LV MPI and any of the CMR parameters. Using receiver operated characteristics analysis, a cutoff value of 0.30 for RV MPI was found to have a sensitivity of 100% and specificity of 74% in predicting a RV ejection fraction <35%. Right ventricular, but not LV, MPI correlated inversely with exercise duration (r = -0.45, P = 0.013) and peak oxygen consumption (VO 2 max) (r = -0.56, P = 0.001). Multivariate analysis identified RV MPI (= -0.6, P < 0.001), male sex (= 0.44, P = 0.01), and duration from surgery (= -0.30, P = 0.019) as significant determinants of VO 2 max. Increased MPI is a reflection of reduced RV ejection fraction and exercise capacity in patients after TOF repair. © Springer Japan 2008.en_US
dc.languageengen_US
dc.publisherSpringer Japan. The Journal's web site is located at www.springerlink.com/openurl.asp?genre=journal&issn=0910-8327en_US
dc.relation.ispartofHeart and Vesselsen_US
dc.subject.meshAdolescenten_US
dc.subject.meshCardiac Surgical Proceduresen_US
dc.subject.meshChilden_US
dc.subject.meshEchocardiography, Doppler, Pulseden_US
dc.subject.meshExercise Testen_US
dc.subject.meshExercise Toleranceen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMagnetic Resonance Imaging, Cineen_US
dc.subject.meshMaleen_US
dc.subject.meshPredictive Value Of Testsen_US
dc.subject.meshPulmonary Circulationen_US
dc.subject.meshRoc Curveen_US
dc.subject.meshSensitivity And Specificityen_US
dc.subject.meshStroke Volumeen_US
dc.subject.meshTetralogy Of Fallot - Pathology - Physiopathology - Surgeryen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVentricular Function, Leften_US
dc.subject.meshVentricular Function, Righten_US
dc.subject.meshYoung Adulten_US
dc.titleFunctional implications of the right ventricular myocardial performance index in patients after surgical repair of tetralogy of Falloten_US
dc.typeArticleen_US
dc.identifier.emailCheung, YF:xfcheung@hku.hken_US
dc.identifier.authorityCheung, YF=rp00382en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/s00380-007-1016-7en_US
dc.identifier.pmid18389336-
dc.identifier.scopuseid_2-s2.0-41849141595en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-41849141595&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume23en_US
dc.identifier.issue2en_US
dc.identifier.spage112en_US
dc.identifier.epage117en_US
dc.identifier.isiWOS:000254756700007-
dc.publisher.placeJapanen_US
dc.identifier.scopusauthoridCheung, EWY=9432819700en_US
dc.identifier.scopusauthoridLam, WWM=35292558200en_US
dc.identifier.scopusauthoridCheung, SCW=17533628600en_US
dc.identifier.scopusauthoridCheung, YF=7202111067en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats