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Article: Serum osteocalcin in normal and short Chinese children

TitleSerum osteocalcin in normal and short Chinese children
Authors
KeywordsGrowth hormone deficiency
Osteocalcin
Short stature
Issue Date1992
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JPC
Citation
Journal Of Paediatrics And Child Health, 1992, v. 28 n. 6, p. 432-435 How to Cite?
AbstractSerum osteocalcin was measured by radioimmunoassay in 200 normal children and adolescents, and seven growth hormone (GH) deficient and seven non-growth hormone deficient (NGHD) short children. There was a sex- and age-dependent change in the serum osteocalcin concentrations in normal children and adolescents with a pattern similar to the childhood height velocity curves. The serum osteocalcin concentration was in the low normal range in most patients with GH deficiency and NGHD short stature. GH therapy significantly increased the growth velocity in both groups of short children. GH treatment resulted in a significant rise in serum osteocalcin concentrations after 6 and 12 months in NGHD children but a more variable change was observed in GH-deficient children. Although osteocalcin levels may given some biochemical indiction of growth, these measurements should be used together with auxological and other biochemical measurements to assess growth reliably.
Persistent Identifierhttp://hdl.handle.net/10722/170256
ISSN
2015 Impact Factor: 1.477
2015 SCImago Journal Rankings: 0.692
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLow, LCKen_HK
dc.contributor.authorLau, YLen_HK
dc.date.accessioned2012-10-30T06:07:01Z-
dc.date.available2012-10-30T06:07:01Z-
dc.date.issued1992en_HK
dc.identifier.citationJournal Of Paediatrics And Child Health, 1992, v. 28 n. 6, p. 432-435en_HK
dc.identifier.issn1034-4810en_HK
dc.identifier.urihttp://hdl.handle.net/10722/170256-
dc.description.abstractSerum osteocalcin was measured by radioimmunoassay in 200 normal children and adolescents, and seven growth hormone (GH) deficient and seven non-growth hormone deficient (NGHD) short children. There was a sex- and age-dependent change in the serum osteocalcin concentrations in normal children and adolescents with a pattern similar to the childhood height velocity curves. The serum osteocalcin concentration was in the low normal range in most patients with GH deficiency and NGHD short stature. GH therapy significantly increased the growth velocity in both groups of short children. GH treatment resulted in a significant rise in serum osteocalcin concentrations after 6 and 12 months in NGHD children but a more variable change was observed in GH-deficient children. Although osteocalcin levels may given some biochemical indiction of growth, these measurements should be used together with auxological and other biochemical measurements to assess growth reliably.en_HK
dc.languageengen_US
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JPCen_HK
dc.relation.ispartofJournal of Paediatrics and Child Healthen_HK
dc.subjectGrowth hormone deficiencyen_HK
dc.subjectOsteocalcinen_HK
dc.subjectShort statureen_HK
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshBody Heighten_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshGrowth Disorders - Blooden_US
dc.subject.meshGrowth Hormone - Deficiencyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshOsteocalcin - Blooden_US
dc.subject.meshRadioimmunoassayen_US
dc.subject.meshReference Valuesen_US
dc.titleSerum osteocalcin in normal and short Chinese childrenen_HK
dc.typeArticleen_HK
dc.identifier.emailLow, LCK: lcklow@hkucc.hku.hken_HK
dc.identifier.emailLau, YL: lauylung@hku.hken_HK
dc.identifier.authorityLow, LCK=rp00337en_HK
dc.identifier.authorityLau, YL=rp00361en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1440-1754.1992.tb02711.x-
dc.identifier.pmid1466937-
dc.identifier.scopuseid_2-s2.0-0026619022en_HK
dc.identifier.volume28en_HK
dc.identifier.issue6en_HK
dc.identifier.spage432en_HK
dc.identifier.epage435en_HK
dc.identifier.isiWOS:A1992KZ37100007-
dc.publisher.placeAustraliaen_HK
dc.identifier.scopusauthoridLow, LCK=7007049461en_HK
dc.identifier.scopusauthoridLau, YL=7201403380en_HK

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