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Article: Surgical treatment of acute TB spondylitis: indications and outcomes

TitleSurgical treatment of acute TB spondylitis: indications and outcomes
Authors
KeywordsDebridement
Instrumentation
Spinal Fusion
Spine
Tuberculosis
Issue Date2013
PublisherSpringer. The Journal's web site is located at http://www.springer.com/medicine/orthopedics/journal/586
Citation
European Spine Journal, 2013, v. 22 suppl. 4, p. S603-S611 How to Cite?
AbstractIntroduction: Spinal tuberculosis represents a challenging disease to treat, not because of the technical expertise or the time required to cure it, but more so because of the decisions involved to treat it. The Medical Research Council (MRC) Working Party on Tuberculosis of the Spine designed trials to help address several questions. Methods: A comprehensive literature search was performed using PubMed Medline, including English articles from 1934 to 1012, which pertain to spinal tuberculosis, with special effort in tracing the 13 MRC reports. The primary focus was on disease eradication, fusion rate, and a secondary focus on both short and long-term results in terms of disease recurrence and alignment. Additional searches were made on the use of spinal implants for infection cases. Results: After reviewing MRC and non-MRC reports, it was evident that the "Hong Kong operation", which involved radical debridement and strut grafting the lesion, produced better short-, medium- and long-term results in such aspects as fusion rate, spinal deformity and relapse of abscess/sinus. Subsequent work by others demonstrated the importance of prevention of progressive kyphosis, therefore the need to identify risk factors for these and pre-emptive measures such as kyphosis correction, careful graft selection, and instrumentation. Conclusion: Improvement in quality of life is also accompanied by higher patient expectations. Though developing nations may lack the resources now, eventually patients will demand better functional and cosmetic results after being afflicted by this disfiguring and potentially disabling disease, and the "Hong Kong operation" represented the best outcome, provided resources were available. © 2012 The Author(s).
Persistent Identifierhttp://hdl.handle.net/10722/170210
ISSN
2015 Impact Factor: 2.132
2015 SCImago Journal Rankings: 0.972
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorMak, KCen_US
dc.contributor.authorCheung, KMCen_US
dc.date.accessioned2012-10-30T06:06:18Z-
dc.date.available2012-10-30T06:06:18Z-
dc.date.issued2013en_US
dc.identifier.citationEuropean Spine Journal, 2013, v. 22 suppl. 4, p. S603-S611en_US
dc.identifier.issn0940-6719en_US
dc.identifier.urihttp://hdl.handle.net/10722/170210-
dc.description.abstractIntroduction: Spinal tuberculosis represents a challenging disease to treat, not because of the technical expertise or the time required to cure it, but more so because of the decisions involved to treat it. The Medical Research Council (MRC) Working Party on Tuberculosis of the Spine designed trials to help address several questions. Methods: A comprehensive literature search was performed using PubMed Medline, including English articles from 1934 to 1012, which pertain to spinal tuberculosis, with special effort in tracing the 13 MRC reports. The primary focus was on disease eradication, fusion rate, and a secondary focus on both short and long-term results in terms of disease recurrence and alignment. Additional searches were made on the use of spinal implants for infection cases. Results: After reviewing MRC and non-MRC reports, it was evident that the "Hong Kong operation", which involved radical debridement and strut grafting the lesion, produced better short-, medium- and long-term results in such aspects as fusion rate, spinal deformity and relapse of abscess/sinus. Subsequent work by others demonstrated the importance of prevention of progressive kyphosis, therefore the need to identify risk factors for these and pre-emptive measures such as kyphosis correction, careful graft selection, and instrumentation. Conclusion: Improvement in quality of life is also accompanied by higher patient expectations. Though developing nations may lack the resources now, eventually patients will demand better functional and cosmetic results after being afflicted by this disfiguring and potentially disabling disease, and the "Hong Kong operation" represented the best outcome, provided resources were available. © 2012 The Author(s).en_US
dc.languageengen_US
dc.publisherSpringer. The Journal's web site is located at http://www.springer.com/medicine/orthopedics/journal/586en_US
dc.relation.ispartofEuropean Spine Journalen_US
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectDebridementen_US
dc.subjectInstrumentationen_US
dc.subjectSpinal Fusionen_US
dc.subjectSpineen_US
dc.subjectTuberculosisen_US
dc.titleSurgical treatment of acute TB spondylitis: indications and outcomesen_US
dc.typeArticleen_US
dc.identifier.emailCheung, KMC:cheungmc@hku.hken_US
dc.identifier.authorityCheung, KMC=rp00387en_US
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1007/s00586-012-2455-0en_US
dc.identifier.pmid22895736-
dc.identifier.scopuseid_2-s2.0-84883504017en_US
dc.identifier.hkuros222918-
dc.identifier.volume22-
dc.identifier.issuesuppl. 4-
dc.identifier.spageS603en_US
dc.identifier.epageS611en_US
dc.identifier.isiWOS:000320884200010-
dc.publisher.placeGermanyen_US
dc.identifier.scopusauthoridMak, KC=51663738600en_US
dc.identifier.scopusauthoridCheung, KMC=7402406754en_US
dc.identifier.citeulike11123683-

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