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Article: Biocompatibility of electrophoretical deposition of nanostructured hydroxyapatite coating on roughen titanium surface: In vitro evaluation using mesenchymal stem cells

TitleBiocompatibility of electrophoretical deposition of nanostructured hydroxyapatite coating on roughen titanium surface: In vitro evaluation using mesenchymal stem cells
Authors
Issue Date2007
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0021-9304:1/
Citation
Journal Of Biomedical Materials Research - Part B Applied Biomaterials, 2007, v. 82 n. 1, p. 183-191 How to Cite?
AbstractA nano hydroxyapatite (HAp) layer was coated on a roughen titanium surface by means of electrophoretic deposition with an acetic anhydride solvent system. The objectives of this current study are to investigate whether nano-HAp can improve mechanical strength at a lower sintering temperature and biocompatibility. Densification temperature was lowered from usual 1000 to 800°C. The coating interfacial bonding strength, phase purity, microstructure, and biocompatibility were investigated. Degradation of HA phase was not detected in XRD. A porous TiO 2 layer acts as a gradient coating layer with an intermediate thermal expansion coefficient between hydroxyapatite and titanium that reduces the thermal stress. From SEM image, the coating does not contain any crack. Mesenchymal stem cell (MSC) is the progenitor cell for various tissues in mature animals, which can improve integration of bone tissue into implant. In this in vitro study, rabbit MSCs culture indicated that the HAp/Ti nanocomposite biomaterial had good biocompatibility and bioactivity. Around materials and on its surface cell grew well with good morphology. Proliferation of the MSCs on the nano-HAp coating was higher than its micron counterpart in XTT assay. These properties show potential for the orthopaedic and dental applications. © 2006 Wiley Periodicals, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/170106
ISSN
2015 Impact Factor: 2.881
2015 SCImago Journal Rankings: 0.784
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChen, Fen_US
dc.contributor.authorLam, WMen_US
dc.contributor.authorLin, CJen_US
dc.contributor.authorQiu, GXen_US
dc.contributor.authorWu, ZHen_US
dc.contributor.authorLuk, KDKen_US
dc.contributor.authorLu, WWen_US
dc.date.accessioned2012-10-30T06:05:22Z-
dc.date.available2012-10-30T06:05:22Z-
dc.date.issued2007en_US
dc.identifier.citationJournal Of Biomedical Materials Research - Part B Applied Biomaterials, 2007, v. 82 n. 1, p. 183-191en_US
dc.identifier.issn1552-4973en_US
dc.identifier.urihttp://hdl.handle.net/10722/170106-
dc.description.abstractA nano hydroxyapatite (HAp) layer was coated on a roughen titanium surface by means of electrophoretic deposition with an acetic anhydride solvent system. The objectives of this current study are to investigate whether nano-HAp can improve mechanical strength at a lower sintering temperature and biocompatibility. Densification temperature was lowered from usual 1000 to 800°C. The coating interfacial bonding strength, phase purity, microstructure, and biocompatibility were investigated. Degradation of HA phase was not detected in XRD. A porous TiO 2 layer acts as a gradient coating layer with an intermediate thermal expansion coefficient between hydroxyapatite and titanium that reduces the thermal stress. From SEM image, the coating does not contain any crack. Mesenchymal stem cell (MSC) is the progenitor cell for various tissues in mature animals, which can improve integration of bone tissue into implant. In this in vitro study, rabbit MSCs culture indicated that the HAp/Ti nanocomposite biomaterial had good biocompatibility and bioactivity. Around materials and on its surface cell grew well with good morphology. Proliferation of the MSCs on the nano-HAp coating was higher than its micron counterpart in XTT assay. These properties show potential for the orthopaedic and dental applications. © 2006 Wiley Periodicals, Inc.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0021-9304:1/en_US
dc.relation.ispartofJournal of Biomedical Materials Research - Part B Applied Biomaterialsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCoated Materials, Biocompatible - Chemistry - Pharmacologyen_US
dc.subject.meshDurapatite - Chemistry - Pharmacologyen_US
dc.subject.meshElectrophoresisen_US
dc.subject.meshMaterials Testingen_US
dc.subject.meshMesenchymal Stem Cells - Drug Effectsen_US
dc.subject.meshNanocomposites - Chemistryen_US
dc.subject.meshParticle Sizeen_US
dc.subject.meshPorosityen_US
dc.subject.meshRabbitsen_US
dc.subject.meshStress, Mechanicalen_US
dc.subject.meshSurface Propertiesen_US
dc.subject.meshTitanium - Chemistryen_US
dc.subject.meshX-Ray Diffractionen_US
dc.titleBiocompatibility of electrophoretical deposition of nanostructured hydroxyapatite coating on roughen titanium surface: In vitro evaluation using mesenchymal stem cellsen_US
dc.typeArticleen_US
dc.identifier.emailLuk, KDK:hcm21000@hku.hken_US
dc.identifier.emailLu, WW:wwlu@hku.hken_US
dc.identifier.authorityLuk, KDK=rp00333en_US
dc.identifier.authorityLu, WW=rp00411en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/jbm.b.30720en_US
dc.identifier.pmid17106895-
dc.identifier.scopuseid_2-s2.0-34347336377en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34347336377&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume82en_US
dc.identifier.issue1en_US
dc.identifier.spage183en_US
dc.identifier.epage191en_US
dc.identifier.isiWOS:000247612600024-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridChen, F=7404908085en_US
dc.identifier.scopusauthoridLam, WM=13403256300en_US
dc.identifier.scopusauthoridLin, CJ=35201257000en_US
dc.identifier.scopusauthoridQiu, GX=7103291762en_US
dc.identifier.scopusauthoridWu, ZH=8668508800en_US
dc.identifier.scopusauthoridLuk, KDK=7201921573en_US
dc.identifier.scopusauthoridLu, WW=7404215221en_US

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