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Article: Expression patterns of the Fam83h gene during murine tooth development

TitleExpression patterns of the Fam83h gene during murine tooth development
Authors
Issue Date2009
PublisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/archoralbio
Citation
Archives Of Oral Biology, 2009, v. 54 n. 9, p. 846-850 How to Cite?
AbstractAim: Recently a novel gene, FAM83H, was identified by a genetic linkage study in the hypocalcified form of the amelogenesis imperfecta family with an autosomal dominant hereditary pattern. Little is known about this novel gene, and so we investigated the expression pattern of Fam83h in murine tooth development using serial sectional in situ hybridisation. Methods and Materials: Using mandibles of ICR mouse at specific developmental stages, in situ hybridisation was performed by DIG-labeled RNA probe. Results: Faint expression was detected in limited cells at embryonic day 14 (E14) in the molar. At the bell stage, E16, Fam83h was localised in the outer and inner enamel epithelium, as well as dental papilla. Fam83h expression begins on E15 in the developing incisor. At E18, Fam83h was expressed in the inner enamel epithelium of the apical bud, ameloblasts and odontoblasts. The expression was stronger in the presecretory stages than the secretory stages. Conclusion: Fam83h was detected in the ameloblasts from the presecretory to the secretory stage, and also the odontoblasts layer and surrounding alveolar bone. © 2009 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/169563
ISSN
2015 Impact Factor: 1.733
2015 SCImago Journal Rankings: 0.713
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLee, MJen_US
dc.contributor.authorLee, SKen_US
dc.contributor.authorLee, KEen_US
dc.contributor.authorKang, HYen_US
dc.contributor.authorJung, HSen_US
dc.contributor.authorKim, JWen_US
dc.date.accessioned2012-10-25T04:52:54Z-
dc.date.available2012-10-25T04:52:54Z-
dc.date.issued2009en_US
dc.identifier.citationArchives Of Oral Biology, 2009, v. 54 n. 9, p. 846-850en_US
dc.identifier.issn0003-9969en_US
dc.identifier.urihttp://hdl.handle.net/10722/169563-
dc.description.abstractAim: Recently a novel gene, FAM83H, was identified by a genetic linkage study in the hypocalcified form of the amelogenesis imperfecta family with an autosomal dominant hereditary pattern. Little is known about this novel gene, and so we investigated the expression pattern of Fam83h in murine tooth development using serial sectional in situ hybridisation. Methods and Materials: Using mandibles of ICR mouse at specific developmental stages, in situ hybridisation was performed by DIG-labeled RNA probe. Results: Faint expression was detected in limited cells at embryonic day 14 (E14) in the molar. At the bell stage, E16, Fam83h was localised in the outer and inner enamel epithelium, as well as dental papilla. Fam83h expression begins on E15 in the developing incisor. At E18, Fam83h was expressed in the inner enamel epithelium of the apical bud, ameloblasts and odontoblasts. The expression was stronger in the presecretory stages than the secretory stages. Conclusion: Fam83h was detected in the ameloblasts from the presecretory to the secretory stage, and also the odontoblasts layer and surrounding alveolar bone. © 2009 Elsevier Ltd. All rights reserved.en_US
dc.languageengen_US
dc.publisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/archoralbioen_US
dc.relation.ispartofArchives of Oral Biologyen_US
dc.subject.meshAlveolar Process - Embryologyen_US
dc.subject.meshAmeloblasts - Cytologyen_US
dc.subject.meshAmelogenesis Imperfecta - Geneticsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshDental Enamel - Embryologyen_US
dc.subject.meshDental Papilla - Embryologyen_US
dc.subject.meshEpithelium - Embryologyen_US
dc.subject.meshGene Expression Regulation, Developmental - Geneticsen_US
dc.subject.meshIn Situ Hybridizationen_US
dc.subject.meshIncisor - Embryologyen_US
dc.subject.meshMesoderm - Cytologyen_US
dc.subject.meshMiceen_US
dc.subject.meshMice, Inbred Icren_US
dc.subject.meshMolar - Embryologyen_US
dc.subject.meshOdontoblasts - Cytologyen_US
dc.subject.meshOdontogenesis - Geneticsen_US
dc.subject.meshProteins - Analysis - Geneticsen_US
dc.subject.meshTooth Germ - Embryologyen_US
dc.titleExpression patterns of the Fam83h gene during murine tooth developmenten_US
dc.typeArticleen_US
dc.identifier.emailJung, HS: hsjung@yuhs.acen_US
dc.identifier.authorityJung, HS=rp01683en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.archoralbio.2009.05.009en_US
dc.identifier.pmid19545854-
dc.identifier.scopuseid_2-s2.0-67651039342en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-67651039342&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume54en_US
dc.identifier.issue9en_US
dc.identifier.spage846en_US
dc.identifier.epage850en_US
dc.identifier.isiWOS:000269290700008-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridLee, MJ=35264472100en_US
dc.identifier.scopusauthoridLee, SK=35102611300en_US
dc.identifier.scopusauthoridLee, KE=8855499100en_US
dc.identifier.scopusauthoridKang, HY=33167578300en_US
dc.identifier.scopusauthoridJung, HS=7403030195en_US
dc.identifier.scopusauthoridKim, JW=34975061900en_US
dc.identifier.citeulike5347272-

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