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Conference Paper: Dysregulated FBI-1 in gestational trophoblastic neoplasms

TitleDysregulated FBI-1 in gestational trophoblastic neoplasms
Authors
Issue Date2011
PublisherAmerican Association for Cancer Research.
Citation
The 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011. How to Cite?
AbstractBACKGROUND: Human placental trophoblast is considered as a pseudo-malignant tissue. Gestational trophoblastic disease (GTD) includes true malignancies such as choriocarcinomas and potentially malignant hydatidiform moles, which may develop into persistent gestational trophoblastic neoplasms requiring chemotherapy. FBI-1 (also called Pokemon/ZBTB7A) is a BTB/POZ-domain Krüppel-like zinc-finger transcription factor which can inactivate p53 through the ARF-MDM2-p53 pathway. This study investigated the expression and functional effects of FBI-1 in choriocarcinomas as compared with ...
DescriptionPoster Session 8 - p53 and Apoptosis Regulation: abstract no. 191
Persistent Identifierhttp://hdl.handle.net/10722/169375

 

DC FieldValueLanguage
dc.contributor.authorMak, VCYen_US
dc.contributor.authorNg, WYen_US
dc.contributor.authorJiang, LLen_US
dc.contributor.authorSiu, MKYen_US
dc.contributor.authorWong, OGWen_US
dc.contributor.authorNgan, HYSen_US
dc.contributor.authorCheung, ANYen_US
dc.date.accessioned2012-10-18T08:52:10Z-
dc.date.available2012-10-18T08:52:10Z-
dc.date.issued2011en_US
dc.identifier.citationThe 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011.en_US
dc.identifier.urihttp://hdl.handle.net/10722/169375-
dc.descriptionPoster Session 8 - p53 and Apoptosis Regulation: abstract no. 191-
dc.description.abstractBACKGROUND: Human placental trophoblast is considered as a pseudo-malignant tissue. Gestational trophoblastic disease (GTD) includes true malignancies such as choriocarcinomas and potentially malignant hydatidiform moles, which may develop into persistent gestational trophoblastic neoplasms requiring chemotherapy. FBI-1 (also called Pokemon/ZBTB7A) is a BTB/POZ-domain Krüppel-like zinc-finger transcription factor which can inactivate p53 through the ARF-MDM2-p53 pathway. This study investigated the expression and functional effects of FBI-1 in choriocarcinomas as compared with ...-
dc.languageengen_US
dc.publisherAmerican Association for Cancer Research.-
dc.relation.ispartofAnnual Meeting of the American Association for Cancer Research, AACR 2011en_US
dc.titleDysregulated FBI-1 in gestational trophoblastic neoplasmsen_US
dc.typeConference_Paperen_US
dc.identifier.emailMak, VCY: h0124398@graduate.hku.hken_US
dc.identifier.emailSiu, MKY: mkysiu@hku.hken_US
dc.identifier.emailWong, OGW: wonggw@hkucc.hku.hken_US
dc.identifier.emailNgan, HYS: hysngan@hkucc.hku.hken_US
dc.identifier.emailCheung, ANY: anycheun@hkucc.hku.hk-
dc.identifier.authoritySiu, MKY=rp00275en_US
dc.identifier.authorityNgan, HYS=rp00346en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros212025en_US
dc.publisher.placeUnited States-
dc.description.otherThe 102nd Annual Meeting of the American Association for Cancer Research (AACR 2011), Orlando, FL., 2-6 April 2011.-

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