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Conference Paper: Study on the interaction between DNA-binding domain (DBD) of human androgen receptor (AR) and SWIRM domain of lysine-specific demethylase 1 (LSD1)
| Title | Study on the interaction between DNA-binding domain (DBD) of human androgen receptor (AR) and SWIRM domain of lysine-specific demethylase 1 (LSD1) |
|---|---|
| Authors | |
| Issue Date | 2011 |
| Citation | The 2011 Croucher Advanced Study Institute Conference on Structure-Based Sreening and Design of Ligands for Protein Targets, Hong Kong, 12-15 December 2011. How to Cite? |
| Abstract | Gene regulations of prokaryotes and eukaryotes are different. Prokaryotic gene regulation requires simply binding of regulatory proteins to help with or avoid forming transcription complex. For eukaryotes like humans, however, their regulation needs “chromatin remodeling” with the association of regulatory proteins involving the opening up of DNA‐histone protein complex chromatin and unwinding DNA. Without remodeling, RNA polymerases responsible of the transcription process cannot get access and perform … |
| Description | Poster Presentation: abstract no. A09 |
| Persistent Identifier | http://hdl.handle.net/10722/169360 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Lo, KC | en_US |
| dc.contributor.author | Zhu, G | en_US |
| dc.contributor.author | Sze, KH | en_US |
| dc.date.accessioned | 2012-10-18T08:51:04Z | - |
| dc.date.available | 2012-10-18T08:51:04Z | - |
| dc.date.issued | 2011 | en_US |
| dc.identifier.citation | The 2011 Croucher Advanced Study Institute Conference on Structure-Based Sreening and Design of Ligands for Protein Targets, Hong Kong, 12-15 December 2011. | en_US |
| dc.identifier.uri | http://hdl.handle.net/10722/169360 | - |
| dc.description | Poster Presentation: abstract no. A09 | - |
| dc.description.abstract | Gene regulations of prokaryotes and eukaryotes are different. Prokaryotic gene regulation requires simply binding of regulatory proteins to help with or avoid forming transcription complex. For eukaryotes like humans, however, their regulation needs “chromatin remodeling” with the association of regulatory proteins involving the opening up of DNA‐histone protein complex chromatin and unwinding DNA. Without remodeling, RNA polymerases responsible of the transcription process cannot get access and perform … | - |
| dc.language | eng | en_US |
| dc.relation.ispartof | Croucher ASI Conference on Structure-Based Sreening and Design of Ligands for Protein Targets | en_US |
| dc.title | Study on the interaction between DNA-binding domain (DBD) of human androgen receptor (AR) and SWIRM domain of lysine-specific demethylase 1 (LSD1) | en_US |
| dc.type | Conference_Paper | en_US |
| dc.identifier.email | Sze, KH: khsze@hku.hk | en_US |
| dc.identifier.authority | Sze, KH=rp00785 | en_US |
| dc.description.nature | postprint | - |
| dc.identifier.hkuros | 211867 | en_US |