File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Induced self-assembly and Förster resonance energy transfer studies of alkynylplatinum(II) terpyridine complex through interaction with water-soluble poly(phenylene ethynylene sulfonate) and the proof-of-principle demonstration of this two-component ensemble for selective label-free detection of human serum albumin

TitleInduced self-assembly and Förster resonance energy transfer studies of alkynylplatinum(II) terpyridine complex through interaction with water-soluble poly(phenylene ethynylene sulfonate) and the proof-of-principle demonstration of this two-component ensemble for selective label-free detection of human serum albumin
Authors
Issue Date2011
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/jacsat/index.html
Citation
Journal Of The American Chemical Society, 2011, v. 133 n. 46, p. 18775-18784 How to Cite?
AbstractThe interaction of conjugated polyelectrolyte, PPE-SO3 -, with platinum(II) complexes, [Pt(tpy)(C≡CC6H 4-CH2NMe3-4)](OTf)2 (1) and [Pt(tpy)(C≡C-CH2NMe3)]-(OTf)2 (2), has been studied by UV-vis, and steady-state and time-resolved emission spectroscopy. A unique FRET from PPE-SO3 - to the aggregated complex 1 on the polymer chain with Pt···Pt interaction has been demonstrated, resulting in the growth of triplet metal-metal-to-ligand charge transfer (3MMLCT) emission in the near-infrared (NIR) region. This two-component ensemble has been employed in a "proof-ofprinciple" concept for the sensitive and selective label-free detection of human serum albumin (HSA) by the emission spectral changes in the visible and in the NIR region. The spectral changes have been ascribed to the disassembly of the polymer-metal complex aggregates upon the binding of PPE-SO3 - to HSA, which is rich in arginine residues and hydrophobic patches, leading to the decrease in FRET from PPE-SO 3 - to the aggregated platinum(II) complex. The ensemble is found to have high selectivity toward HSA over a number of polyelectrolytes, proteins and small amino acids. This has been suggested to be a result of the extra stabilization gained from the Pt··· Pt and π-π interactions in addition to the electrostatic and hydrophobic interactions found in the polymer-metal complex aggregates. © 2011 American Chemical Society.
Persistent Identifierhttp://hdl.handle.net/10722/168594
ISSN
2015 Impact Factor: 13.038
2015 SCImago Journal Rankings: 7.123
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChung, CYSen_US
dc.contributor.authorYam, VWWen_US
dc.date.accessioned2012-10-08T03:21:17Z-
dc.date.available2012-10-08T03:21:17Z-
dc.date.issued2011en_US
dc.identifier.citationJournal Of The American Chemical Society, 2011, v. 133 n. 46, p. 18775-18784en_US
dc.identifier.issn0002-7863en_US
dc.identifier.urihttp://hdl.handle.net/10722/168594-
dc.description.abstractThe interaction of conjugated polyelectrolyte, PPE-SO3 -, with platinum(II) complexes, [Pt(tpy)(C≡CC6H 4-CH2NMe3-4)](OTf)2 (1) and [Pt(tpy)(C≡C-CH2NMe3)]-(OTf)2 (2), has been studied by UV-vis, and steady-state and time-resolved emission spectroscopy. A unique FRET from PPE-SO3 - to the aggregated complex 1 on the polymer chain with Pt···Pt interaction has been demonstrated, resulting in the growth of triplet metal-metal-to-ligand charge transfer (3MMLCT) emission in the near-infrared (NIR) region. This two-component ensemble has been employed in a "proof-ofprinciple" concept for the sensitive and selective label-free detection of human serum albumin (HSA) by the emission spectral changes in the visible and in the NIR region. The spectral changes have been ascribed to the disassembly of the polymer-metal complex aggregates upon the binding of PPE-SO3 - to HSA, which is rich in arginine residues and hydrophobic patches, leading to the decrease in FRET from PPE-SO 3 - to the aggregated platinum(II) complex. The ensemble is found to have high selectivity toward HSA over a number of polyelectrolytes, proteins and small amino acids. This has been suggested to be a result of the extra stabilization gained from the Pt··· Pt and π-π interactions in addition to the electrostatic and hydrophobic interactions found in the polymer-metal complex aggregates. © 2011 American Chemical Society.en_US
dc.languageengen_US
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/jacsat/index.htmlen_US
dc.relation.ispartofJournal of the American Chemical Societyen_US
dc.titleInduced self-assembly and Förster resonance energy transfer studies of alkynylplatinum(II) terpyridine complex through interaction with water-soluble poly(phenylene ethynylene sulfonate) and the proof-of-principle demonstration of this two-component ensemble for selective label-free detection of human serum albuminen_US
dc.typeArticleen_US
dc.identifier.emailYam, VWW:wwyam@hku.hken_US
dc.identifier.authorityYam, VWW=rp00822en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1021/ja205996een_US
dc.identifier.pmid22035316-
dc.identifier.scopuseid_2-s2.0-83055186864en_US
dc.identifier.hkuros204651-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-83055186864&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume133en_US
dc.identifier.issue46en_US
dc.identifier.spage18775en_US
dc.identifier.epage18784en_US
dc.identifier.isiWOS:000297398900049-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridChung, CYS=35169000200en_US
dc.identifier.scopusauthoridYam, VWW=18539304700en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats