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Article: Heme oxygenase-1 system and gastrointestinal tumors

TitleHeme oxygenase-1 system and gastrointestinal tumors
Authors
Issue Date2010
PublisherBeijing Baishideng BioMed Scientific Co., Ltd. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htm
Citation
World Journal Of Gastroenterology, 2010, v. 16 n. 21, p. 2633-2637 How to Cite?
Abstract
Heme oxygenase-1 (HO-1) system catabolizes heme into three products: carbon monoxide, biliverdin/bilirubin and free iron. It is involved in many physiological and pathophysiological processes. A great deal of data has demonstrated the roles of HO-1 in the formation, growth and metastasis of tumors. The interest in this system by investigators involved in gastrointestinal tumors is fairly recent, and few papers on HO-1 have touched upon this subject. This review focuses on the current understanding of the physiological significance of HO-1 induction and its possible roles in the gastrointestinal tumors studied to date. The implications for possible therapeutic manipulation of HO-1 in gastrointestinal tumors are also discussed. © 2010 Baishideng. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/168463
ISSN
2013 Impact Factor: 2.433
2013 SCImago Journal Rankings: 1.022
PubMed Central ID
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZhu, Xen_US
dc.contributor.authorFan, WGen_US
dc.contributor.authorLi, DPen_US
dc.contributor.authorLin, MCMen_US
dc.contributor.authorKung, Hen_US
dc.date.accessioned2012-10-08T03:19:15Z-
dc.date.available2012-10-08T03:19:15Z-
dc.date.issued2010en_US
dc.identifier.citationWorld Journal Of Gastroenterology, 2010, v. 16 n. 21, p. 2633-2637en_US
dc.identifier.issn1007-9327en_US
dc.identifier.urihttp://hdl.handle.net/10722/168463-
dc.description.abstractHeme oxygenase-1 (HO-1) system catabolizes heme into three products: carbon monoxide, biliverdin/bilirubin and free iron. It is involved in many physiological and pathophysiological processes. A great deal of data has demonstrated the roles of HO-1 in the formation, growth and metastasis of tumors. The interest in this system by investigators involved in gastrointestinal tumors is fairly recent, and few papers on HO-1 have touched upon this subject. This review focuses on the current understanding of the physiological significance of HO-1 induction and its possible roles in the gastrointestinal tumors studied to date. The implications for possible therapeutic manipulation of HO-1 in gastrointestinal tumors are also discussed. © 2010 Baishideng. All rights reserved.en_US
dc.languageengen_US
dc.publisherBeijing Baishideng BioMed Scientific Co., Ltd. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htmen_US
dc.relation.ispartofWorld Journal of Gastroenterologyen_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshEnzyme Inductionen_US
dc.subject.meshGastrointestinal Neoplasms - Enzymology - Pathologyen_US
dc.subject.meshHeme - Metabolismen_US
dc.subject.meshHeme Oxygenase-1 - Genetics - Metabolismen_US
dc.subject.meshHumansen_US
dc.subject.meshIsoenzymes - Genetics - Metabolismen_US
dc.subject.meshPolymorphism, Geneticen_US
dc.subject.meshPromoter Regions, Geneticen_US
dc.titleHeme oxygenase-1 system and gastrointestinal tumorsen_US
dc.typeArticleen_US
dc.identifier.emailLin, MCM:mcllin@hkucc.hku.hken_US
dc.identifier.authorityLin, MCM=rp00746en_US
dc.description.naturepublished_or_final_versionen_US
dc.identifier.doi10.3748/wjg.v16.i21.2633en_US
dc.identifier.pmid20518085en_US
dc.identifier.pmcidPMC2880776-
dc.identifier.scopuseid_2-s2.0-77953512037en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77953512037&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume16en_US
dc.identifier.issue21en_US
dc.identifier.spage2633en_US
dc.identifier.epage2637en_US
dc.identifier.isiWOS:000278519300009-
dc.publisher.placeChinaen_US
dc.identifier.scopusauthoridZhu, X=23491117800en_US
dc.identifier.scopusauthoridFan, WG=24070406000en_US
dc.identifier.scopusauthoridLi, DP=24463373900en_US
dc.identifier.scopusauthoridLin, MCM=7404816359en_US
dc.identifier.scopusauthoridKung, H=7402514190en_US

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