File Download
 
Links for fulltext
(May Require Subscription)
 
Supplementary

Article: Heme oxygenase-1 system and gastrointestinal tumors
  • Basic View
  • Metadata View
  • XML View
TitleHeme oxygenase-1 system and gastrointestinal tumors
 
AuthorsZhu, X3
Fan, WG2
Li, DP2
Lin, MCM1
Kung, H4
 
Issue Date2010
 
PublisherBeijing Baishideng BioMed Scientific Co., Ltd. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htm
 
CitationWorld Journal Of Gastroenterology, 2010, v. 16 n. 21, p. 2633-2637 [How to Cite?]
DOI: http://dx.doi.org/10.3748/wjg.v16.i21.2633
 
AbstractHeme oxygenase-1 (HO-1) system catabolizes heme into three products: carbon monoxide, biliverdin/bilirubin and free iron. It is involved in many physiological and pathophysiological processes. A great deal of data has demonstrated the roles of HO-1 in the formation, growth and metastasis of tumors. The interest in this system by investigators involved in gastrointestinal tumors is fairly recent, and few papers on HO-1 have touched upon this subject. This review focuses on the current understanding of the physiological significance of HO-1 induction and its possible roles in the gastrointestinal tumors studied to date. The implications for possible therapeutic manipulation of HO-1 in gastrointestinal tumors are also discussed. © 2010 Baishideng. All rights reserved.
 
ISSN1007-9327
2012 Impact Factor: 2.547
2012 SCImago Journal Rankings: 0.785
 
DOIhttp://dx.doi.org/10.3748/wjg.v16.i21.2633
 
PubMed Central IDPMC2880776
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorZhu, X
 
dc.contributor.authorFan, WG
 
dc.contributor.authorLi, DP
 
dc.contributor.authorLin, MCM
 
dc.contributor.authorKung, H
 
dc.date.accessioned2012-10-08T03:19:15Z
 
dc.date.available2012-10-08T03:19:15Z
 
dc.date.issued2010
 
dc.description.abstractHeme oxygenase-1 (HO-1) system catabolizes heme into three products: carbon monoxide, biliverdin/bilirubin and free iron. It is involved in many physiological and pathophysiological processes. A great deal of data has demonstrated the roles of HO-1 in the formation, growth and metastasis of tumors. The interest in this system by investigators involved in gastrointestinal tumors is fairly recent, and few papers on HO-1 have touched upon this subject. This review focuses on the current understanding of the physiological significance of HO-1 induction and its possible roles in the gastrointestinal tumors studied to date. The implications for possible therapeutic manipulation of HO-1 in gastrointestinal tumors are also discussed. © 2010 Baishideng. All rights reserved.
 
dc.description.naturePublished_or_final_version
 
dc.identifier.citationWorld Journal Of Gastroenterology, 2010, v. 16 n. 21, p. 2633-2637 [How to Cite?]
DOI: http://dx.doi.org/10.3748/wjg.v16.i21.2633
 
dc.identifier.doihttp://dx.doi.org/10.3748/wjg.v16.i21.2633
 
dc.identifier.epage2637
 
dc.identifier.issn1007-9327
2012 Impact Factor: 2.547
2012 SCImago Journal Rankings: 0.785
 
dc.identifier.issue21
 
dc.identifier.pmcidPMC2880776
 
dc.identifier.pmid20518085
 
dc.identifier.scopuseid_2-s2.0-77953512037
 
dc.identifier.spage2633
 
dc.identifier.urihttp://hdl.handle.net/10722/168463
 
dc.identifier.volume16
 
dc.languageeng
 
dc.publisherBeijing Baishideng BioMed Scientific Co., Ltd. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htm
 
dc.publisher.placeChina
 
dc.relation.ispartofWorld Journal of Gastroenterology
 
dc.relation.referencesReferences in Scopus
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
 
dc.subject.meshEnzyme Induction
 
dc.subject.meshGastrointestinal Neoplasms - Enzymology - Pathology
 
dc.subject.meshHeme - Metabolism
 
dc.subject.meshHeme Oxygenase-1 - Genetics - Metabolism
 
dc.subject.meshHumans
 
dc.subject.meshIsoenzymes - Genetics - Metabolism
 
dc.subject.meshPolymorphism, Genetic
 
dc.subject.meshPromoter Regions, Genetic
 
dc.titleHeme oxygenase-1 system and gastrointestinal tumors
 
dc.typeArticle
 
<?xml encoding="utf-8" version="1.0"?>
<item><contributor.author>Zhu, X</contributor.author>
<contributor.author>Fan, WG</contributor.author>
<contributor.author>Li, DP</contributor.author>
<contributor.author>Lin, MCM</contributor.author>
<contributor.author>Kung, H</contributor.author>
<date.accessioned>2012-10-08T03:19:15Z</date.accessioned>
<date.available>2012-10-08T03:19:15Z</date.available>
<date.issued>2010</date.issued>
<identifier.citation>World Journal Of Gastroenterology, 2010, v. 16 n. 21, p. 2633-2637</identifier.citation>
<identifier.issn>1007-9327</identifier.issn>
<identifier.uri>http://hdl.handle.net/10722/168463</identifier.uri>
<description.abstract>Heme oxygenase-1 (HO-1) system catabolizes heme into three products: carbon monoxide, biliverdin/bilirubin and free iron. It is involved in many physiological and pathophysiological processes. A great deal of data has demonstrated the roles of HO-1 in the formation, growth and metastasis of tumors. The interest in this system by investigators involved in gastrointestinal tumors is fairly recent, and few papers on HO-1 have touched upon this subject. This review focuses on the current understanding of the physiological significance of HO-1 induction and its possible roles in the gastrointestinal tumors studied to date. The implications for possible therapeutic manipulation of HO-1 in gastrointestinal tumors are also discussed. &#169; 2010 Baishideng. All rights reserved.</description.abstract>
<language>eng</language>
<publisher>Beijing Baishideng BioMed Scientific Co., Ltd. The Journal&apos;s web site is located at http://www.wjgnet.com/1007-9327/index.htm</publisher>
<relation.ispartof>World Journal of Gastroenterology</relation.ispartof>
<rights>Creative Commons: Attribution 3.0 Hong Kong License</rights>
<subject.mesh>Enzyme Induction</subject.mesh>
<subject.mesh>Gastrointestinal Neoplasms - Enzymology - Pathology</subject.mesh>
<subject.mesh>Heme - Metabolism</subject.mesh>
<subject.mesh>Heme Oxygenase-1 - Genetics - Metabolism</subject.mesh>
<subject.mesh>Humans</subject.mesh>
<subject.mesh>Isoenzymes - Genetics - Metabolism</subject.mesh>
<subject.mesh>Polymorphism, Genetic</subject.mesh>
<subject.mesh>Promoter Regions, Genetic</subject.mesh>
<title>Heme oxygenase-1 system and gastrointestinal tumors</title>
<type>Article</type>
<description.nature>Published_or_final_version</description.nature>
<identifier.doi>10.3748/wjg.v16.i21.2633</identifier.doi>
<identifier.pmid>20518085</identifier.pmid>
<identifier.pmcid>PMC2880776</identifier.pmcid>
<identifier.scopus>eid_2-s2.0-77953512037</identifier.scopus>
<relation.references>http://www.scopus.com/mlt/select.url?eid=2-s2.0-77953512037&amp;selection=ref&amp;src=s&amp;origin=recordpage</relation.references>
<identifier.volume>16</identifier.volume>
<identifier.issue>21</identifier.issue>
<identifier.spage>2633</identifier.spage>
<identifier.epage>2637</identifier.epage>
<publisher.place>China</publisher.place>
<bitstream.url>http://hub.hku.hk/bitstream/10722/168463/1/content.pdf</bitstream.url>
</item>
Author Affiliations
  1. Prince of Wales Hospital Hong Kong
  2. Sun Yat-Sen University
  3. Guangzhou Medical College
  4. Chinese University of Hong Kong