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Article: Synthesis of chiral β3-aminoxy peptides

TitleSynthesis of chiral β3-aminoxy peptides
Authors
Issue Date2004
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/joc
Citation
Journal Of Organic Chemistry, 2004, v. 69 n. 22, p. 7577-7581 How to Cite?
AbstractA series of chiral β3-aminoxy acids or amides with various side chains have been synthesized via two different approaches. One is the Arndt-Eistert homologation approach, using chiral α-aminoxy acids as starting materials. The other approach, utilizing the enantioselective reduction of β-keto esters catalyzed by baker's yeast or chiral Ru(II) complexes, produces chiral β3-aminoxy acids with nonproteinaceous side chains. The oligomers of β3-aminoxy acids can be readily prepared using EDCI/HOAt as the coupling reagent.
Persistent Identifierhttp://hdl.handle.net/10722/168370
ISSN
2015 Impact Factor: 4.785
2015 SCImago Journal Rankings: 2.095
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYang, Den_US
dc.contributor.authorZhang, YHen_US
dc.contributor.authorLi, Ben_US
dc.contributor.authorZhang, DWen_US
dc.date.accessioned2012-10-08T03:18:04Z-
dc.date.available2012-10-08T03:18:04Z-
dc.date.issued2004en_US
dc.identifier.citationJournal Of Organic Chemistry, 2004, v. 69 n. 22, p. 7577-7581en_US
dc.identifier.issn0022-3263en_US
dc.identifier.urihttp://hdl.handle.net/10722/168370-
dc.description.abstractA series of chiral β3-aminoxy acids or amides with various side chains have been synthesized via two different approaches. One is the Arndt-Eistert homologation approach, using chiral α-aminoxy acids as starting materials. The other approach, utilizing the enantioselective reduction of β-keto esters catalyzed by baker's yeast or chiral Ru(II) complexes, produces chiral β3-aminoxy acids with nonproteinaceous side chains. The oligomers of β3-aminoxy acids can be readily prepared using EDCI/HOAt as the coupling reagent.en_US
dc.languageengen_US
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/jocen_US
dc.relation.ispartofJournal of Organic Chemistryen_US
dc.subject.meshAmides - Chemical Synthesisen_US
dc.subject.meshAmino Acids - Chemical Synthesisen_US
dc.subject.meshCatalysisen_US
dc.subject.meshMolecular Structureen_US
dc.subject.meshNuclear Magnetic Resonance, Biomolecularen_US
dc.subject.meshPeptides - Chemical Synthesisen_US
dc.subject.meshStereoisomerismen_US
dc.titleSynthesis of chiral β3-aminoxy peptidesen_US
dc.typeArticleen_US
dc.identifier.emailYang, D:yangdan@hku.hken_US
dc.identifier.authorityYang, D=rp00825en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1021/jo049174fen_US
dc.identifier.pmid15497984-
dc.identifier.scopuseid_2-s2.0-6444239844en_US
dc.identifier.hkuros102005-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-6444239844&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume69en_US
dc.identifier.issue22en_US
dc.identifier.spage7577en_US
dc.identifier.epage7581en_US
dc.identifier.isiWOS:000224707900022-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridYang, D=7404800756en_US
dc.identifier.scopusauthoridZhang, YH=8379010100en_US
dc.identifier.scopusauthoridLi, B=36072052100en_US
dc.identifier.scopusauthoridZhang, DW=35320759400en_US

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