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Article: Physiologically stable vanadium(IV) porphyrins as a new class of anti-HIV agents

TitlePhysiologically stable vanadium(IV) porphyrins as a new class of anti-HIV agents
Authors
Issue Date2005
PublisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp
Citation
Chemical Communications, 2005 n. 28, p. 3544-3546 How to Cite?
Abstract
The water soluble oxovanadium(IV) tetraarylporphyrin 1a has demonstrated excellent solution stability against glutathione reduction and high potency (5 μM, 97% inhibition) in inhibiting HIV-1 replication in Hut/CCR5 cells. © The Royal Society of Chemistry 2005.
Persistent Identifierhttp://hdl.handle.net/10722/167966
ISSN
2013 Impact Factor: 6.718
2013 SCImago Journal Rankings: 2.918
ISI Accession Number ID
References

 

Author Affiliations
  1. The University of Hong Kong
  2. Institute of Molecular Technology for Drug Discovery and Synthesis, Hong Kong
DC FieldValueLanguage
dc.contributor.authorWong, SYen_US
dc.contributor.authorSun, RWYen_US
dc.contributor.authorChung, NPYen_US
dc.contributor.authorLin, CLen_US
dc.contributor.authorChe, CMen_US
dc.date.accessioned2012-10-08T03:13:32Z-
dc.date.available2012-10-08T03:13:32Z-
dc.date.issued2005en_US
dc.identifier.citationChemical Communications, 2005 n. 28, p. 3544-3546en_US
dc.identifier.issn1359-7345en_US
dc.identifier.urihttp://hdl.handle.net/10722/167966-
dc.description.abstractThe water soluble oxovanadium(IV) tetraarylporphyrin 1a has demonstrated excellent solution stability against glutathione reduction and high potency (5 μM, 97% inhibition) in inhibiting HIV-1 replication in Hut/CCR5 cells. © The Royal Society of Chemistry 2005.en_US
dc.languageengen_US
dc.publisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.aspen_US
dc.relation.ispartofChemical Communicationsen_US
dc.subject.meshAnti-Hiv Agents - Chemistry - Pharmacologyen_US
dc.subject.meshCell Lineen_US
dc.subject.meshDose-Response Relationship, Drugen_US
dc.subject.meshDrug Stabilityen_US
dc.subject.meshGlutathione - Metabolismen_US
dc.subject.meshHumansen_US
dc.subject.meshMetalloporphyrins - Chemistry - Pharmacologyen_US
dc.subject.meshOxidation-Reductionen_US
dc.subject.meshReceptors, Ccr5en_US
dc.subject.meshSolubilityen_US
dc.subject.meshVanadium Compounds - Chemistry - Pharmacologyen_US
dc.subject.meshVirus Replication - Drug Effectsen_US
dc.titlePhysiologically stable vanadium(IV) porphyrins as a new class of anti-HIV agentsen_US
dc.typeArticleen_US
dc.identifier.emailSun, RWY:rwysun@hku.hken_US
dc.identifier.emailChe, CM:cmche@hku.hken_US
dc.identifier.authoritySun, RWY=rp00781en_US
dc.identifier.authorityChe, CM=rp00670en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1039/b503535jen_US
dc.identifier.pmid16010318en_US
dc.identifier.scopuseid_2-s2.0-27644475402en_US
dc.identifier.hkuros117879-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-27644475402&selection=ref&src=s&origin=recordpageen_US
dc.identifier.issue28en_US
dc.identifier.spage3544en_US
dc.identifier.epage3546en_US
dc.identifier.isiWOS:000230399400010-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridWong, SY=24582723200en_US
dc.identifier.scopusauthoridSun, RWY=26325835800en_US
dc.identifier.scopusauthoridChung, NPY=9271796700en_US
dc.identifier.scopusauthoridLin, CL=49763478200en_US
dc.identifier.scopusauthoridChe, CM=7102442791en_US

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