Article: Physiologically stable vanadium(iv) porphyrins as a new class of anti-HIV agents

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TitlePhysiologically stable vanadium(iv) porphyrins as a new class of anti-HIV agents
AuthorsWong, SY2
Sun, RWY2
Chung, NPY1
Lin, CL1
Che, CM2
Issue Date2005
PublisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp
CitationChemical Communications, 2005 n. 28, p. 3544-3546 [How to Cite?]
DOI: http://dx.doi.org/10.1039/b503535j
AbstractThe water soluble oxovanadium(iv) tetraarylporphyrin 1a has demonstrated excellent solution stability against glutathione reduction and high potency (5 μM, 97% inhibition) in inhibiting HIV-1 replication in Hut/CCR5 cells. © The Royal Society of Chemistry 2005.
ISSN1359-7345
2011 Impact Factor: 6.169
2011 SCImago Journal Rankings: 0.507
DOIhttp://dx.doi.org/10.1039/b503535j
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorWong, SY
dc.contributor.authorSun, RWY
dc.contributor.authorChung, NPY
dc.contributor.authorLin, CL
dc.contributor.authorChe, CM
dc.date.accessioned2012-10-08T03:13:32Z
dc.date.available2012-10-08T03:13:32Z
dc.date.issued2005
dc.description.abstractThe water soluble oxovanadium(iv) tetraarylporphyrin 1a has demonstrated excellent solution stability against glutathione reduction and high potency (5 μM, 97% inhibition) in inhibiting HIV-1 replication in Hut/CCR5 cells. © The Royal Society of Chemistry 2005.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationChemical Communications, 2005 n. 28, p. 3544-3546 [How to Cite?]
DOI: http://dx.doi.org/10.1039/b503535j
dc.identifier.doihttp://dx.doi.org/10.1039/b503535j
dc.identifier.epage3546
dc.identifier.issn1359-7345
2011 Impact Factor: 6.169
2011 SCImago Journal Rankings: 0.507
dc.identifier.issue28
dc.identifier.pmid16010318
dc.identifier.scopuseid_2-s2.0-27644475402
dc.identifier.spage3544
dc.identifier.urihttp://hdl.handle.net/10722/167966
dc.languageeng
dc.publisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp
dc.publisher.placeUnited Kingdom
dc.relation.ispartofChemical Communications
dc.relation.referencesReferences in Scopus
dc.subject.meshAnti-Hiv Agents - Chemistry - Pharmacology
dc.subject.meshCell Line
dc.subject.meshDose-Response Relationship, Drug
dc.subject.meshDrug Stability
dc.subject.meshGlutathione - Metabolism
dc.subject.meshHumans
dc.subject.meshMetalloporphyrins - Chemistry - Pharmacology
dc.subject.meshOxidation-Reduction
dc.subject.meshReceptors, Ccr5
dc.subject.meshSolubility
dc.subject.meshVanadium Compounds - Chemistry - Pharmacology
dc.subject.meshVirus Replication - Drug Effects
dc.titlePhysiologically stable vanadium(iv) porphyrins as a new class of anti-HIV agents
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong
  2. Institute of Molecular Technology for Drug Discovery and Synthesis, Hong Kong