File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1002/cbdv.200590092
- Scopus: eid_2-s2.0-26044436557
- PMID: 17193204
- WOS: WOS:000232226900009
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Synthesis and biological evaluation of novel compounds related to 1-arylnaphthalene lignans and isoquinolines
Title | Synthesis and biological evaluation of novel compounds related to 1-arylnaphthalene lignans and isoquinolines |
---|---|
Authors | |
Issue Date | 2005 |
Publisher | Wiley - V C H Verlag GmbH & Co KGaA. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/106056929 |
Citation | Chemistry And Biodiversity, 2005, v. 2 n. 9, p. 1217-1231 How to Cite? |
Abstract | Novel compounds designed as hybrids of 1-arylnaphthalene lignans with isoquinoline alkaloids were prepared and evaluated for their cytotoxicities on human tumor cell lines, such as A549, Hela, PC-3, CNE, BEL-7404, and KB. Some of the synthetic compounds exhibited their IC 50 values on selected cell lines at 10 -6 m scale. The preliminary CoMFA molecular-modelling studies of these synthetic analogues were also performed. © 2005 Verlag Helvetica Chimica Acta AG, Zürich. |
Persistent Identifier | http://hdl.handle.net/10722/167959 |
ISSN | 2021 Impact Factor: 2.745 2020 SCImago Journal Rankings: 0.427 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ding, H | en_US |
dc.contributor.author | Lu, W | en_US |
dc.contributor.author | Li, H | en_US |
dc.contributor.author | Yang, L | en_US |
dc.contributor.author | Zhang, Q | en_US |
dc.contributor.author | Zhou, C | en_US |
dc.contributor.author | Wu, X | en_US |
dc.contributor.author | Baudoin, O | en_US |
dc.contributor.author | Cai, J | en_US |
dc.contributor.author | Guéritte, F | en_US |
dc.contributor.author | Zhao, Y | en_US |
dc.date.accessioned | 2012-10-08T03:13:26Z | - |
dc.date.available | 2012-10-08T03:13:26Z | - |
dc.date.issued | 2005 | en_US |
dc.identifier.citation | Chemistry And Biodiversity, 2005, v. 2 n. 9, p. 1217-1231 | en_US |
dc.identifier.issn | 1612-1872 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/167959 | - |
dc.description.abstract | Novel compounds designed as hybrids of 1-arylnaphthalene lignans with isoquinoline alkaloids were prepared and evaluated for their cytotoxicities on human tumor cell lines, such as A549, Hela, PC-3, CNE, BEL-7404, and KB. Some of the synthetic compounds exhibited their IC 50 values on selected cell lines at 10 -6 m scale. The preliminary CoMFA molecular-modelling studies of these synthetic analogues were also performed. © 2005 Verlag Helvetica Chimica Acta AG, Zürich. | en_US |
dc.language | eng | en_US |
dc.publisher | Wiley - V C H Verlag GmbH & Co KGaA. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/106056929 | en_US |
dc.relation.ispartof | Chemistry and Biodiversity | en_US |
dc.subject.mesh | Antineoplastic Agents - Chemistry - Pharmacology | en_US |
dc.subject.mesh | Cell Line, Tumor | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Isoquinolines - Chemistry - Pharmacology | en_US |
dc.subject.mesh | Lignans - Chemistry - Pharmacology | en_US |
dc.subject.mesh | Models, Molecular | en_US |
dc.subject.mesh | Molecular Structure | en_US |
dc.title | Synthesis and biological evaluation of novel compounds related to 1-arylnaphthalene lignans and isoquinolines | en_US |
dc.type | Article | en_US |
dc.identifier.email | Lu, W:luwei@hku.hk | en_US |
dc.identifier.authority | Lu, W=rp00754 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1002/cbdv.200590092 | en_US |
dc.identifier.pmid | 17193204 | - |
dc.identifier.scopus | eid_2-s2.0-26044436557 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-26044436557&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 2 | en_US |
dc.identifier.issue | 9 | en_US |
dc.identifier.spage | 1217 | en_US |
dc.identifier.epage | 1231 | en_US |
dc.identifier.isi | WOS:000232226900009 | - |
dc.publisher.place | Germany | en_US |
dc.identifier.scopusauthorid | Ding, H=24400944500 | en_US |
dc.identifier.scopusauthorid | Lu, W=27868087600 | en_US |
dc.identifier.scopusauthorid | Li, H=40861398300 | en_US |
dc.identifier.scopusauthorid | Yang, L=8356794700 | en_US |
dc.identifier.scopusauthorid | Zhang, Q=7406715139 | en_US |
dc.identifier.scopusauthorid | Zhou, C=7403347317 | en_US |
dc.identifier.scopusauthorid | Wu, X=12144456600 | en_US |
dc.identifier.scopusauthorid | Baudoin, O=6601962392 | en_US |
dc.identifier.scopusauthorid | Cai, J=26643616800 | en_US |
dc.identifier.scopusauthorid | Guéritte, F=7004196029 | en_US |
dc.identifier.scopusauthorid | Zhao, Y=7406634118 | en_US |
dc.identifier.issnl | 1612-1872 | - |