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Article: Management of anovulatory infertility

TitleManagement of anovulatory infertility
Authors
KeywordsAnovulatory Subfertility
Anti-Oestrogen
Aromatase Inhibitor
Dopamine Agonist
Gonadotrophin
Ovarian Drilling
Pulsatile Gnrh
Weight Management
Issue Date2012
PublisherBailliere Tindall. The Journal's web site is located at http://www.elsevier.com/locate/bpobgyn
Citation
Bailliere's Best Practice And Research In Clinical Obstetrics And Gynaecology, 2012, v. 26 n. 6, p. 757-768 How to Cite?
AbstractAnovulatory subfertility is a heterogeneous condition with various underlying causes, which should be identified with appropriate history taking, physical examination and relevant investigations. Optimisation of body weight is essential in either underweight, overweight or obese individuals. Women with hypogonadotrophic anovulation can be treated with pulsatile gonadotrophin-releasing hormone therapy or a gonadotrophin preparation containing both follicle-stimulating hormone or luteinising hormone activities. For normogonadotrophic anovulation, clomiphene citrate should be used as first-line medical treatment. Metformin co-treatment with clomiphene citrate may be considered in a subgroup of women with polycystic ovary syndrome who are obese or clomiphene-resistant. Ovulation induction with gonadotrophin or laparoscopic ovarian drilling is the next option. Dopamine agonist is indicated for anovulation as a result of hyperprolactinaemia. © 2012 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/167096
ISSN
2015 Impact Factor: 2.291
2015 SCImago Journal Rankings: 1.123
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLi, RHWen_US
dc.contributor.authorNg, EHYen_US
dc.date.accessioned2012-09-28T04:03:40Z-
dc.date.available2012-09-28T04:03:40Z-
dc.date.issued2012en_US
dc.identifier.citationBailliere's Best Practice And Research In Clinical Obstetrics And Gynaecology, 2012, v. 26 n. 6, p. 757-768en_US
dc.identifier.issn1521-6934en_US
dc.identifier.urihttp://hdl.handle.net/10722/167096-
dc.description.abstractAnovulatory subfertility is a heterogeneous condition with various underlying causes, which should be identified with appropriate history taking, physical examination and relevant investigations. Optimisation of body weight is essential in either underweight, overweight or obese individuals. Women with hypogonadotrophic anovulation can be treated with pulsatile gonadotrophin-releasing hormone therapy or a gonadotrophin preparation containing both follicle-stimulating hormone or luteinising hormone activities. For normogonadotrophic anovulation, clomiphene citrate should be used as first-line medical treatment. Metformin co-treatment with clomiphene citrate may be considered in a subgroup of women with polycystic ovary syndrome who are obese or clomiphene-resistant. Ovulation induction with gonadotrophin or laparoscopic ovarian drilling is the next option. Dopamine agonist is indicated for anovulation as a result of hyperprolactinaemia. © 2012 Elsevier Ltd. All rights reserved.en_US
dc.languageengen_US
dc.publisherBailliere Tindall. The Journal's web site is located at http://www.elsevier.com/locate/bpobgynen_US
dc.relation.ispartofBailliere's Best Practice and Research in Clinical Obstetrics and Gynaecologyen_US
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication in Bailliere's Best Practice And Research In Clinical Obstetrics And Gynaecology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Bailliere's Best Practice And Research In Clinical Obstetrics And Gynaecology, 2012, v. 26 n. 6, p. 757-768. DOI: 10.1016/j.bpobgyn.2012.05.004-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectAnovulatory Subfertilityen_US
dc.subjectAnti-Oestrogenen_US
dc.subjectAromatase Inhibitoren_US
dc.subjectDopamine Agonisten_US
dc.subjectGonadotrophinen_US
dc.subjectOvarian Drillingen_US
dc.subjectPulsatile Gnrhen_US
dc.subjectWeight Managementen_US
dc.titleManagement of anovulatory infertilityen_US
dc.typeArticleen_US
dc.identifier.emailLi, RHW: raymondli@hku.hken_US
dc.identifier.emailNg, EHY: nghye@hku.hken_US
dc.identifier.authorityLi, RHW=rp01649en_US
dc.identifier.authorityNg, EHY=rp00426en_US
dc.description.naturepostprinten_US
dc.identifier.doi10.1016/j.bpobgyn.2012.05.004en_US
dc.identifier.pmid22703626-
dc.identifier.scopuseid_2-s2.0-84867891189en_US
dc.identifier.hkuros222175-
dc.identifier.isiWOS:000310948000005-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridLi, RHW=7404724295en_US
dc.identifier.scopusauthoridNg, EHY=35238184300en_US

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