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Article: Excess mortality associated with the 2009 pandemic of influenza A(H1N1) in Hong Kong
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TitleExcess mortality associated with the 2009 pandemic of influenza A(H1N1) in Hong Kong
 
AuthorsYang, L1
Chan, KP1
Cowling, BJ1
Chiu, SS1
Chan, KH1
Peiris, JSM1 2
Wong, CM1
 
Issue Date2012
 
PublisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=HYG
 
CitationEpidemiology and Infection, 2012, v. 140 n. 9, p. 1542-1550 [How to Cite?]
DOI: http://dx.doi.org/10.1017/S0950268811002238
 
AbstractReliable estimates of the burden of 2009 pandemic influenza A(pH1N1) cannot be easily obtained because only a small fraction of infections were confirmed by laboratory tests in a timely manner. In this study we developed a Poisson prediction modelling approach to estimate the excess mortality associated with pH1N1 in 2009 and seasonal influenza in 1998-2008 in the subtropical city Hong Kong. The results suggested that there were 127 all-cause excess deaths associated with pH1N1, including 115 with cardiovascular and respiratory disease, and 22 with pneumonia and influenza. The excess mortality rates associated with pH1N1 were highest in the population aged >/=65 years. The mortality burden of influenza during the whole of 2009 was comparable to those in the preceding ten inter-pandemic years. The estimates of excess deaths were more than twofold higher than the reported fatal cases with laboratory-confirmed pH1N1 infection.
 
ISSN0950-2688
2013 Impact Factor: 2.491
 
DOIhttp://dx.doi.org/10.1017/S0950268811002238
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorYang, L
 
dc.contributor.authorChan, KP
 
dc.contributor.authorCowling, BJ
 
dc.contributor.authorChiu, SS
 
dc.contributor.authorChan, KH
 
dc.contributor.authorPeiris, JSM
 
dc.contributor.authorWong, CM
 
dc.date.accessioned2012-09-20T08:48:05Z
 
dc.date.available2012-09-20T08:48:05Z
 
dc.date.issued2012
 
dc.description.abstractReliable estimates of the burden of 2009 pandemic influenza A(pH1N1) cannot be easily obtained because only a small fraction of infections were confirmed by laboratory tests in a timely manner. In this study we developed a Poisson prediction modelling approach to estimate the excess mortality associated with pH1N1 in 2009 and seasonal influenza in 1998-2008 in the subtropical city Hong Kong. The results suggested that there were 127 all-cause excess deaths associated with pH1N1, including 115 with cardiovascular and respiratory disease, and 22 with pneumonia and influenza. The excess mortality rates associated with pH1N1 were highest in the population aged >/=65 years. The mortality burden of influenza during the whole of 2009 was comparable to those in the preceding ten inter-pandemic years. The estimates of excess deaths were more than twofold higher than the reported fatal cases with laboratory-confirmed pH1N1 infection.
 
dc.description.naturelink_to_subscribed_fulltext
 
dc.identifier.citationEpidemiology and Infection, 2012, v. 140 n. 9, p. 1542-1550 [How to Cite?]
DOI: http://dx.doi.org/10.1017/S0950268811002238
 
dc.identifier.doihttp://dx.doi.org/10.1017/S0950268811002238
 
dc.identifier.epage1550
 
dc.identifier.hkuros208340
 
dc.identifier.issn0950-2688
2013 Impact Factor: 2.491
 
dc.identifier.issue9
 
dc.identifier.pmid22074735
 
dc.identifier.scopuseid_2-s2.0-84864469778
 
dc.identifier.spage1542
 
dc.identifier.urihttp://hdl.handle.net/10722/166781
 
dc.identifier.volume140
 
dc.languageeng
 
dc.publisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=HYG
 
dc.publisher.placeUnited Kingdom
 
dc.relation.ispartofEpidemiology and Infection
 
dc.relation.referencesReferences in Scopus
 
dc.rightsEpidemiology and Infection. Copyright © Cambridge University Press.
 
dc.subject.meshCause of Death
 
dc.subject.meshInfluenza A Virus, H1N1 Subtype - isolation and purification
 
dc.subject.meshInfluenza, Human - complications - epidemiology - mortality
 
dc.subject.meshModels, Biological
 
dc.subject.meshPandemics
 
dc.titleExcess mortality associated with the 2009 pandemic of influenza A(H1N1) in Hong Kong
 
dc.typeArticle
 
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<contributor.author>Cowling, BJ</contributor.author>
<contributor.author>Chiu, SS</contributor.author>
<contributor.author>Chan, KH</contributor.author>
<contributor.author>Peiris, JSM</contributor.author>
<contributor.author>Wong, CM</contributor.author>
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Author Affiliations
  1. The University of Hong Kong
  2. HKU-Pasteur Research Centre